File:Dynamic alterations in the paternal epigenetic landscape following fertilization F1.jpg
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Alterations to the epigenome post-fertilization.
Summary
[edit]DescriptionDynamic alterations in the paternal epigenetic landscape following fertilization F1.jpg |
English: The top panel illustrates the chromatin structure of the mature sperm immediately following fertilization (highly protaminated with some retension of paternally derived histones). From the following cell is seen the protamine to histone transition where maternally derived histones replace protamines resulting in the decondensation of the sperm head. The middle panel illustrates the various stages of early embryonic development. The bottom panel shows the methylation changes that occur over time in the maternal and paternal pronucleus, where the paternal pronucleus undergoes active demethylation and the maternal DNA is demethylated passively in a replication dependent manner. The approximate chronology of major events in the early embryo is outlined along the bottom of the figure and correlates to the illustrations of embryos above. (text from article) |
Date | |
Source | Jenkins, Timothy G. (2012). "Dynamic alterations in the paternal epigenetic landscape following fertilization". Frontiers in Genetics 3: 143. DOI:10.3389/fgene.2012.00143. PMID 23024648. PMC: 3442791. ISSN 1664-8021. |
Author | Timothy G. Jenkins and Douglas T. Carrell |
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current | 16:42, 28 February 2020 | ![]() | 1,500 × 1,130 (248 KB) | Helixitta (talk | contribs) | User created page with UploadWizard |
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Author | Douglas T. Carrell |
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Orientation | Normal |
Horizontal resolution | 300 dpi |
Vertical resolution | 300 dpi |
Software used | Adobe Photoshop CS5 Windows |
File change date and time | 15:58, 27 July 2012 |
Color space | sRGB |
Date and time of digitizing | 15:01, 27 July 2012 |
Date metadata was last modified | 21:28, 27 July 2012 |
Unique ID of original document | uuid:af372d9b-bc41-49ba-a0e2-b665c8370659 |
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