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1.
High-frequency SiPM readout advances measured coincidence time resolution limits in TOF-PET / Gundacker, Stefan (Milan Bicocca U. ; CERN) ; Turtos, Rosana Martinez (CERN) ; Auffray, Etiennette (CERN) ; Paganoni, Marco (Milan Bicocca U.) ; Lecoq, Paul (CERN)
Scintillator based radiation detectors readout by SiPMs successively break records in their reached time resolution. Nevertheless, new challenges in time of flight positron emission tomography (TOF-PET) and high energy physics are setting unmatched goals in the 10 ps range. [...]
2019 - 10 p. - Published in : Physics in Medicine & Biology 64 (2019) 055012 Fulltext: PDF;
2.
Experimental time resolution limits of modern SiPMs and TOF-PET detectors exploring different scintillators and Cherenkov emission / Gundacker, Stefan (Milan Bicocca U. ; CERN) ; Martinez Turtos, Rosana (CERN) ; Kratochwil, Nicolaus (CERN ; Vienna U.) ; Pots, Rosalinde Hendrika (CERN ; RWTH Aachen U.) ; Paganoni, Marco (Milan Bicocca U. ; CERN) ; Lecoq, Paul (CERN) ; Auffray, Etiennette (CERN)
Solid state photodetectors like silicon photomultipliers (SiPMs) are playing an important role in several fields of medical imaging, life sciences and high energy physics. They are able to sense optical photons with a single photon detection time precision below 100 ps, making them ideal candidates to read the photons generated by fast scintillators in time of flight positron emission tomography (TOF-PET). [...]
2020 - 20 p. - Published in : Phys. Med. Biol. 65 (2020) 025001 Fulltext: PDF;
3.
State of the art timing in TOF-PET detectors with LuAG, GAGG and L(Y)SO scintillators of various sizes coupled to FBK-SiPMs / Gundacker, S. (CERN) ; Acerbi, F. (Fond. Bruno Kessler, Trento) ; Auffray, E. (CERN) ; Ferri, A. (Fond. Bruno Kessler, Trento) ; Gola, A. (Fond. Bruno Kessler, Trento) ; Nemallapudi, M.V. (CERN) ; Paternoster, G. (Fond. Bruno Kessler, Trento) ; Piemonte, C. (Fond. Bruno Kessler, Trento) ; Lecoq, P. (CERN)
Time of flight (TOF) in positron emission tomography (PET) has experienced a revival of interest after its first introduction in the eighties. This is due to a significant progress in solid state photodetectors (SiPMs) and newly developed scintillators (LSO and its derivatives). [...]
2016 - Published in : JINST 11 (2016) P08008 IOP Open Access article: PDF;
4.
Pushing Cherenkov PET with BGO via coincidence time resolution classification and correction / Kratochwil, Nicolaus (CERN ; Vienna U. ; [email protected]) ; Gundacker, Stefan (CERN ; Milan Bicocca U.) ; Lecoq, Paul (CERN) ; Auffray, Etiennette (CERN)
Bismuth germanate (BGO) shows good properties for positron emission tomography (PET) applications, but was substituted by the development of faster crystals like lutetium oxyorthosilicate (LSO) for time-of-flight PET (TOF-PET). Recent improvements in silicon photomultipliers (SiPMs) and fast readout electronics make it possible to access the Cherenkov photon signal produced upon 511 keV interaction, which makes BGO a cost-effective candidate for TOF-PET. [...]
2020 - 7 p. - Published in : Phys. Med. Biol. 65 (2020) 115004 Fulltext: PDF;
5.
Improved single photon time resolution for analog SiPMs with front end readout that reduces influence of electronic noise / Cates, Joshua W (Stanford U.) ; Gundacker, Stefan (CERN ; Milan Bicocca U.) ; Auffray, Etiennette (CERN) ; Lecoq, Paul (CERN) ; Levin, Craig S (Stanford U.)
A key step to improve the coincidence time resolution of positron emission tomography detectors that exploit small populations of promptly emitted photons is improving the single photon time resolution (SPTR) of silicon photomultipliers (SiPMs). The influence of electronic noise has previously been identified as the dominant factor affecting SPTR for large area, analog SiPMs. [...]
2018 - 11 p. - Published in : Phys. Med. Biol. 63 (2018) 185022
6.
Performance evaluation of the FastIC readout ASIC with emphasis on Cherenkov emission in TOF-PET / Piller, Markus (CERN ; Graz U.) ; Castilla, Antonio M (Barcelona U.) ; Terragni, Giulia (CERN ; Vienna, Tech. U.) ; Alozy, Jerome (CERN) ; Auffray, Etiennette (CERN) ; Ballabriga, Rafael (CERN ; Barcelona U.) ; Campbell, Michael (CERN) ; Deutschmann, Bernd (Graz U.) ; Gascon, David (Barcelona U.) ; Gola, Alberto (Fond. Bruno Kessler, Trento) et al.
Objective. The efficient usage of prompt photons like Cherenkov emission is of great interest for the design of the next generation, cost-effective, and ultra-high-sensitivity time-of-flight positron emission tomography (TOF-PET) scanners. [...]
2024 - 13 p. - Published in : Phys. Med. Biol. 69 (2024) 115014 Fulltext: PDF;
7.
Exploring Cherenkov emission of BGO for TOF-PET / Kratochwil, Nicolaus (CERN ; Vienna U.) ; Auffray, Etiennette (CERN) ; Gundacker, Stefan (CERN)
Bismuth germanate (BGO) was the preferred crystal for PET scanners, but was substituted with the emergence of faster crystals. Improvements in Silicon Photomultipliers (SiPMs) and the use of fast high frequency readout make it possible to use the prompt Cherenkov emission in BGO in order to boost the achievable coincidence time resolution significantly. The large fluctuations in the detected Cherenkov photon yield are causing time or amplitude walk effects in the leading edge time discrimination, which are corrected by measuring the initial signal rise time via a double threshold system. [...]
2021 - 12 p. - Published in : IEEE Trans. Rad. Plasma Med. Sci. 5 (2021) 619 Fulltext from publisher: PDF;
8.
Petiroc2A: Characterization and Experimental Results / Ahmad, Salleh (Weeroc SAS, Palaiseau) ; Fleury, Julien (Weeroc SAS, Palaiseau) ; Cizel, Jean-Baptiste (Weeroc SAS, Palaiseau) ; de la Taille, Christophe (Ec. Polytech., OMEGA) ; Seguin-Moreau, Natalie (Ec. Polytech., OMEGA) ; Gundacker, Stefan (CERN ; Milan Bicocca U.) ; Auffray-Hillemanns, Etiennette (CERN)
Petiroc2A is a 32-channel SiPM readout ASIC, which has been designed for applications requiring precise timing and energy measurement such as time-of-flight positron emission tomography. In this work, experimental results of Petiroc2A are presented. [...]
2019 - 4 p. - Published in : 10.1109/NSSMIC.2018.8824464
In : 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC 2018), Sydney, Australia, 10 - 17 Nov 2018, pp.1
9.
Systematic study of new types of Hamamatsu MPPCs read out with the NINO ASIC / Doroud, K (Enrico Fermi Ctr., Rome) ; Rodriguez, A (CERN ; World Lab., Geneva) ; Williams, M C S (CERN ; INFN, Bologna ; Bologna U.) ; Yamamoto, K (Hamamatsu Photonics) ; Zichichi, A (CERN ; Enrico Fermi Ctr., Rome ; INFN, Bologna ; Bologna U.) ; Zuyeuski, R (CERN ; World Lab., Geneva)
Over the last decade there have been commercial TOF-PET scanners constructed using Photo-Multiplier Tubes (PMT) that have achieved View the MathML source~500ps FWHM Coincidence Time Resolution (CTR). A new device known as the Silicon PhotoMultiplier (SiPM) has the potential to overcome some of the limitations of the PMT. [...]
2014 - 5 p. - Published in : Nucl. Instrum. Methods Phys. Res., A 753 (2014) 149-153 Elsevier Open Access article: PDF;
10.
Endo-TOFPET-US: A multimodal ultrasonic probe featuring time of flight PET in diagnostic and therapeutic endoscopy / Meyer, T.C (CERN) /for the Endo-TOFPET-US Collaboration
This work outlines the functionality of a new medical instrument and describes the research and development work aiming at new and higher performance imaging techniques with Time of Flight-PET capability in endoscopy and surgical oncology. It focuses on the associated scientific and technological challenges to be met in fields such as scintillating crystallography, ultra-fast photo-detection, highly integrated electronics, and system integration. [...]
2013 - 5 p. - Published in : Nucl. Instrum. Methods Phys. Res., A 718 (2013) 121-125
In : 12th Pisa Meeting on Advanced Detectors: Frontier Detector for Frontier Physics, La Biodola, Isola d'Elba, Italy, 20 - 26 May 2012, pp.121-125

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