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1.
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South East European International Institute for Sustainable Technologies (SEEIIST)
/ Amaldi, Ugo (TERA, Novara) ; Benedetto, Elena (TERA, Novara) ; Damjanovic, Sanja (Unlisted, CH) ; Dosanjh, Manjit (CERN) ; Durante, Marco (Darmstadt, GSI ; Darmstadt, Tech. U.) ; Georgieva, Petya (TERA, Novara) ; Haberer, Thomas (HITS, Heidelberg) ; Plesko, Mark (Cosylab, Ljubljana) ; Ristova, Mimoza (CERN ; Skopje U.) ; Rossi, Sandro (Unlisted, IT) et al.
The South East European International Institute for Sustainable Technologies (SEEIIST) was
proposed in 2016 at the World Academy of Art and Science, with the objective of building a
facility for charged particle cancer therapy for the South Eastern European countries. SEEIIST
will offer the world-class research needed to reduce or even revert the brain drain that is causing
a shortage of talent and economic losses in South East Europe. [...]
2021
- Published in : Front. Phys. 8 (2021) 567466
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Dosimetric validation of Monte Carlo and analytical dose engines with raster-scanning $^1$H, $^4$He, $^{12}$C, and $^{16}$O ion-beams using an anthropomorphic phantom
/ Mein, Stewart (NCRO, Heidelberg ; Heidelberg U. Hospital ; DKFZ, Heidelberg) ; Kopp, Benedikt (Heidelberg U. Hospital ; Heidelberg U. ; DKFZ, Heidelberg) ; Tessonnier, Thomas (Centre Francois Baclesse, Caen) ; Ackermann, Benjamin (Heidelberg U. Hospital) ; Ecker, Swantje (Heidelberg U. Hospital) ; Bauer, Julia (Heidelberg U. Hospital) ; Choi, Kyungdon (CNAO, Pavia) ; Aricò, Giulia (CERN) ; Ferrari, Alfredo (CERN) ; Haberer, Thomas (Heidelberg U. Hospital) et al.
With high-precision radiotherapy on the rise towards mainstream healthcare, comprehensive validation procedures are essential, especially as more sophisticated technologies emerge. In preparation for the upcoming
translation of novel ions, case-/disease-specific ion-beam selection and advanced multi-particle treatment
modalities at the Heidelberg Ion-beam Therapy Center (HIT), we quantify the accuracy limits in particle therapy
treatment planning under complex heterogeneous conditions for the four ions ($^1$H, $^4$He, $^{12}$C, $^{16}$O) using a Monte
Carlo Treatment Planning platform (MCTP), an independent GPU-accelerated analytical dose engine developed
in-house (FRoG) and the clinical treatment planning system (Syngo RT Planning). [...]
2019 - 9 p.
- Published in : Physica Medica 64 (2019) 123-131
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3.
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Towards a Common Reliability & Availability Information System for Particle Accelerator Facilities
/ Höppner, Klaus (HITS, Heidelberg) ; Gutleber, Johannes (CERN) ; Haberer, Thomas (HITS, Heidelberg) ; Humer, Heinrich (TU Vienna) ; Niemi, Arto (CERN) ; Pasic, Kemal (HITS, Heidelberg) ; Peters, Andreas (HITS, Heidelberg)
Failure event and maintenance record based data collection systems have a long tradition in industry. Today, the particle accelerator community does not possess a common platform that permits storing and sharing reliability and availability information in an efficient way. [...]
2020 - 4 p.
- Published in : 10.18429/JACoW-ICALEPCS2019-MOPHA063
Fulltext: PDF;
In : 17th Biennial International Conference on Accelerator and Large Experimental Physics Control Systems (ICALEPCS), New York, United States, 5 - 11 Oct 2019, pp.356
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4.
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A novel facility for cancer therapy and biomedical research with heavy ions for the South East European International Institute for Sustainable Technologies
/ Damjanovic, Sanja (SEEIIST Association (CH)) ; Amaldi, Ugo (TERA Foundation (IT)) ; Benedetto, Elena (SEEIIST Association (CH)) ; Bisoffi, Giovanni (Universita e INFN, Legnaro (IT)) ; Dosanjh, Manjit ; Durante, Marco ; Foka, Yiota (GSI - Helmholtzzentrum fur Schwerionenforschung GmbH (DE)) ; Grubling, Peter (SEEIIST Association (CH)) ; Rossi, Sandro ; Sapinski, Mariusz (SEEIIST Association (CH)) et al.
The South East European International Institute for Sustainable Technologies (SEEIIST) proposes the construction of a major joint Research Infrastructure in the region, to rebuild cooperation after the recent wars and overcome lasting consequences like technology deficits and brain drain, having at its core a facility for cancer therapy and biomedical research with heavy ions. [...]
CERN-ACC-NOTE-2021-0019 ; NIMMS-Note-005.
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2021. - 4 p.
Full text - Full text
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5.
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South East European International Institute for Sustainable Technologies (SEEIIST)
/ Amaldi, Ugo (TERA, Novara) ; Benedetto, Elena (TERA, Novara) ; Damjanovic, Sanja (SEEIIST Association) ; Dosanjh, Manjit (CERN ; U. Oxford (main)) ; Durante, Marco (Darmstadt, GSI ; Darmstadt, Tech. U.) ; Georgieva, Petya (TERA, Novara) ; Haberer, Thomas (HITS, Heidelberg) ; Plesko, Mark (Cosylab, Ljubljana) ; Ristova, Mimoza (SEEIIST Association ; Faculty of Natural Sciences, UKIM, Skopje, North Macedonia) ; Rossi, Sandro (CNAO) et al.
The South East European International Institute for Sustainable Technologies (SEEIIST) was proposed in 2016 at the World Academy of Art and Science, with the objective of building a facility for charged particle cancer therapy for the South Eastern European countries. [...]
15 p.
Full text
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6.
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Measurement of $^4$He charge- and mass-changing cross sections on H, C, O, and Si targets in the energy range 70–220 MeV/u for radiation transport calculations in ion-beam therapy
/ Horst, Felix (Giessen U. ; Darmstadt, GSI) ; Aricò, Giulia (CERN) ; Brinkmann, Kai-Thomas (U. Giessen, II. Phys. Inst.) ; Brons, Stephan (Heidelberg U.) ; Ferrari, Alfredo (CERN) ; Haberer, Thomas (Heidelberg U.) ; Mairani, Andrea (Heidelberg U. ; CNAO, Pavia) ; Parodi, Katia (Munich U.) ; Reidel, Claire-Anne (Darmstadt, GSI ; Strasbourg, IPHC) ; Weber, Uli (Darmstadt, GSI) et al.
Measured charge- and mass-changing cross sections for the systems He4+C12, He4+O16, He4+Si28, and He4+H1 in the energy range 70–220MeV/u are presented. The cross sections were obtained via the attenuation method where a ΔE-E scintillator telescope was used for particle identification. [...]
2019 - 11 p.
- Published in : Phys. Rev. C 99 (2019) 014603
Fulltext from publisher: PDF;
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7.
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Next generation multi-scale biophysical characterization of high precision cancer particle radiotherapy using clinical proton, helium-, carbon- and oxygen ion beams
/ Dokic, Ivana (Heidelberg, Inst. Radiology ; HITS, Heidelberg ; Heidelberg U. Hospital) ; Mairani, Andrea (HITS, Heidelberg ; CNAO, Milan) ; Niklas, Martin (Heidelberg, Inst. Radiology ; HITS, Heidelberg ; Heidelberg U. Hospital) ; Zimmermann, Ferdinand (Heidelberg, Inst. Radiology ; HITS, Heidelberg ; Heidelberg U. Hospital) ; Chaudhri, Naved (HITS, Heidelberg) ; Krunic, Damir (Heidelberg, Inst. Radiology) ; Tessonnier, Thomas (Heidelberg U. Hospital ; Munich U.) ; Ferrari, Alfredo (CERN) ; Parodi, Katia (HITS, Heidelberg ; Munich U.) ; Jäkel, Oliver (HITS, Heidelberg ; Heidelberg, Inst. Radiology) et al.
The growing number of particle therapy facilities worldwide landmarks a novel era of precision oncology. Implementation of robust biophysical readouts is urgently needed to assess the efficacy of different radiation qualities. [...]
2016 - 14 p.
- Published in : Oncotarget 7 (2016) 56676-56689
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8.
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Towards clinical evidence in particle therapy: ENLIGHT, PARTNER, ULICE and beyond
/ Combs, Stephanie E (U. Hospital Heidelberg) ; Djosanjh, Manjit (CERN) ; Pötter, Richad (AKH Wien) ; Orrechia, Roberto (Istituto Europeo di Oncologia, Milan) ; Haberer, Thomas (HIT, Heidelberg) ; Durante, Marco (GSI, Darmstadt) ; Fossati, Piero (CNAO, Pavia) ; Parodi, Katia (Munich U.) ; Balosso, Jacques (GCS-ETOILE, Lyon) ; Amaldi, Ugo (CERN) et al.
Since the middle of the 20th century, particle therapy has been in focus for patient treatments. In 1946, Robert Wilson proposed the use of charged particles for tumor therapy, and since then, the clinical use of protons and heavier ions, mainly carbon ions, has become more widespread. [...]
2013
- Published in : J. Radiat. Res. 54 (2013) i6-i12
Oxford Univ. Press Open Access article: PDF;
In : PARTNER, pp.i6-i12
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