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CONCEPTUAL DESIGN OF A COMPACT SYNCHROTRON-BASED FACILITY FOR CANCER THERAPY AND BIOMEDICAL RESEARCH WITH HELIUM AND PROTONS BEAMS
/ Vretenar, Maurizio (CERN) ; Angoletta, Maria Elena (CERN) ; Borburgh, Jan (CERN) ; Bottura, Luca (CERN) ; Taylor, Rebecca (Imperial College (GB)) ; Tranquille, Gerard Alain (CERN) ; Benedetto, Elena (SEEIIST Association (CH)) ; Torims, Toms (Riga Technical University (LV)) ; Palskis, Kristaps (Riga Technical University (LV)) ; Sapinski, Mariusz (Paul Scherrer Institute (CH)) et al.
Thanks to their superior dose conformality and higher radiobiological effectiveness with respect to protons, helium ions are considered as the new tool of choice in the fight against cancer using particle beams [...]
CERN-ACC-NOTE-2023-0012 ; NIMMS-Note-018.
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2023. - 6 p.
Full text
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A Compact Synchrotron for Advanced Cancer Therapy with Helium and Proton Beams
/ Vretenar, Maurizio (CERN) ; Angoletta, Maria Elena (CERN) ; Benedetto, Elena (U. Geneva (main)) ; Bisoffi, Giovanni (INFN, Legnaro) ; Borburgh, Jan (CERN) ; Bottura, Luca (CERN) ; Paļskis, Kristaps (CERN) ; Sapinski, Mariusz (PSI, Villigen) ; Taylor, Rebecca (CERN) ; Tranquille, Gerard (CERN)
Recent years have seen an increased interest in the use of helium for radiation therapy of cancer. Helium ions can be more precisely delivered to the tumour than protons or carbon ions, presently the only beams licensed for treatment, with a biological effectiveness between the two. [...]
2022 - 4 p.
- Published in : JACoW IPAC 2022 (2022) 811-814
Fulltext: PDF;
In : 13th International Particle Accelerator Conference (IPAC 2022), Bangkok, Thailand, 12 - 17 Jun 2022, pp.811-814
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Slow Extraction Modelling for NIMMS Hadron Therapy Synchrotrons
/ Taylor, Rebecca (CERN) ; Benedetto, Elena (Geneva Observ.) ; Pasternak, Jaroslaw (Imperial Coll., London) ; Sapinski, Mariusz (U. Geneva (main))
The Next Ion Medical Machine Study (NIMMS) is an umbrella R&D; programme for CERN accelerator technologies targeting advanced accelerator options for proton and light ion therapy. In collaboration with the European program HITRIplus, one area of study is slow extraction which is required to deliver a uniform beam spill for radiotherapy treatment. [...]
2022 - 4 p.
- Published in : JACoW IPAC 2022 (2022) 2988-2991
Fulltext: PDF;
In : 13th International Particle Accelerator Conference (IPAC 2022), Bangkok, Thailand, 12 - 17 Jun 2022, pp.2988-2991
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Review of Technologies for Ion Therapy Accelerators
/ Norman, H X Q (Manchester U. ; RMIT U.) ; Appleby, Robert (Manchester U. ; Daresbury) ; Benedetto, Elena (IBM, Geneva) ; Owen, Hywel (Manchester U. ; RMIT U.) ; Sapinski, Mariusz (IBM, Geneva) ; Sheehy, Suzanne (Melbourne U.) ; Steinberg, A F (Manchester U. ; RMIT U.)
Cancer therapy using protons and heavier ions such as carbon has demonstrated advantages over other radiotherapy treatments. To bring about the next generation of clinical facilities, the requirements are likely to reduce the footprint, obtain beam intensities above 1E10 particles per spill, and achieve faster extraction for more rapid, flexible treatment. [...]
arXiv:2105.08103.-
Geneva : JACoW, 2021 - 4 p.
- Published in : JACoW IPAC 2021 (2021) 2465-2468
Fulltext: 2105.08103 - PDF; document - PDF;
In : 12th International Particle Accelerator Conference (IPAC 2021), Online, 24 - 28 May 2021, pp.2465-2468
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A COMPACT SYNCHROTRON FOR ADVANCED CANCER THERAPY WITH HELIUM AND PROTON BEAMS
/ Vretenar, Maurizio (CERN) ; Angoletta, Maria Elena (CERN) ; Bisoffi, Giovanni (Universita e INFN, Legnaro (IT)) ; Borburgh, Jan (CERN) ; Bottura, Luca (CERN) ; Palskis, Kristaps (Riga Technical University (LV)) ; Tranquille, Gerard Alain (CERN) ; Benedetto, Elena (SEEIIST Association (CH)) ; Sapinski, Mariusz (Paul Scherrer Institute (CH)) ; Taylor, Rebecca Louise (CERN)
Recent years have seen an increased interest in the use of helium for radiation therapy of cancer. [...]
CERN-ACC-NOTE-2022-0018 ; CERN-ACC-NOTE-2022-018 ; NIMMS-Note-010.
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2022. - 4 p.
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South East European International Institute for Sustainable Technologies (SEEIIST)
/ Amaldi, Ugo (TERA, Novara) ; Benedetto, Elena (TERA, Novara) ; Damjanovic, Sanja (Unlisted, CH) ; Dosanjh, Manjit (CERN) ; Durante, Marco (Darmstadt, GSI ; Darmstadt, Tech. U.) ; Georgieva, Petya (TERA, Novara) ; Haberer, Thomas (HITS, Heidelberg) ; Plesko, Mark (Cosylab, Ljubljana) ; Ristova, Mimoza (CERN ; Skopje U.) ; Rossi, Sandro (Unlisted, IT) et al.
The South East European International Institute for Sustainable Technologies (SEEIIST) was
proposed in 2016 at the World Academy of Art and Science, with the objective of building a
facility for charged particle cancer therapy for the South Eastern European countries. SEEIIST
will offer the world-class research needed to reduce or even revert the brain drain that is causing
a shortage of talent and economic losses in South East Europe. [...]
2021
- Published in : Front. Phys. 8 (2021) 567466
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A novel facility for cancer therapy and biomedical research with heavy ions for the South East European International Institute for Sustainable Technologies
/ Damjanovic, Sanja (SEEIIST Association (CH)) ; Amaldi, Ugo (TERA Foundation (IT)) ; Benedetto, Elena (SEEIIST Association (CH)) ; Bisoffi, Giovanni (Universita e INFN, Legnaro (IT)) ; Dosanjh, Manjit ; Durante, Marco ; Foka, Yiota (GSI - Helmholtzzentrum fur Schwerionenforschung GmbH (DE)) ; Grubling, Peter (SEEIIST Association (CH)) ; Rossi, Sandro ; Sapinski, Mariusz (SEEIIST Association (CH)) et al.
The South East European International Institute for Sustainable Technologies (SEEIIST) proposes the construction of a major joint Research Infrastructure in the region, to rebuild cooperation after the recent wars and overcome lasting consequences like technology deficits and brain drain, having at its core a facility for cancer therapy and biomedical research with heavy ions. [...]
CERN-ACC-NOTE-2021-0019 ; NIMMS-Note-005.
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2021. - 4 p.
Full text - Full text
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The next ion medical machine study at CERN: Towards a next generation cancer research and therapy facility with ion beams
/ Vretenar, Maurizio (CERN) ; Bencini, Vittorio (TERA Foundation (IT)) ; Khalvati, Mohammad Reza ; Lombardi, Alessandra (CERN) ; Tommasini, Davide (CERN) ; Benedetto, Elena (SEEIIST Association (CH)) ; Sapinski, Mariusz (SEEIIST Association (CH)) ; Foka, Yiota (GSI - Helmholtzzentrum fur Schwerionenforschung GmbH (DE))
Cancer therapy with ions has several advantages over X- ray and proton therapy, but its diffusion remains limited primarily because of the size and cost of the accelerator. To develop technologies that might improve performance and reduce accelerator cost with respect to present facilities, CERN has recently launched the Next Ion Medical Ma-chine Study (NIMMS), leveraging CERN expertise in accelerator fields to disseminate technologies developed for basic science. [...]
CERN-ACC-NOTE-2021-0018; NIMMS-Note-004.-
Geneva : CERN, 2021 - 6 p.
- Published in : JACoW IPAC2021 (2021) MOPAB413
Fulltext: document (3) - ; NIMMS_Note_004_Final - PDF;
In : 12th International Particle Accelerator Conference (IPAC 2021), Online, 24 - 28 May 2021, pp.MOPAB413
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