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1.
Enhancing timing performance of heterostructures with double-sided readout / Pagano, Fiammetta (CERN ; Milan Bicocca U. ; Valencia, Polytechnic U.) ; Kratochwil, Nicolaus (CERN ; UC, Davis) ; Lowis, Carsten (CERN ; RWTH Aachen U.) ; Choong, Woon-Seng (LBNL, Berkeley) ; Paganoni, Marco (CERN ; Milan Bicocca U.) ; Pizzichemi, Marco (CERN ; Milan Bicocca U.) ; Cates, Joshua W (LBNL, Berkeley) ; Auffray, Etiennette (CERN)
Objective. Heterostructured scintillators offer a promising solution to balance the sensitivity and timing in TOF-PET detectors. [...]
2024 - 13 p. - Published in : Phys. Med. Biol. 69 (2024) 205012 Fulltext: PDF;
2.
First investigation of the morphological and luminescence properties of HfO$_2$ nanoparticles synthesized by photochemical synthesis / Villa, Irene (Prague, Inst. Phys.) ; Procházková, Lenka Prouzová (Prague, Inst. Phys. ; Prague, Tech. U.) ; Mihóková, Eva (Prague, Inst. Phys.) ; Babin, Vladimir (Prague, Inst. Phys.) ; Král, Robert (Prague, Inst. Phys.) ; Zemenová, Petra (Prague, Inst. Phys.) ; Falvey, Alexandra (Prague, Inst. Phys.) ; Čuba, Václav (Prague, Tech. U.) ; Salomoni, Matteo (CERN ; Milan Bicocca U.) ; Pagano, Fiammetta (CERN ; Milan Bicocca U.) et al.
For the first time, hafnia (HfO$_2$) nanoparticles have been produced by photochemical synthesis. The photochemical route has been proven to be scalable, affordable, and straightforward to create monoclinic HfO$_2$ nanoparticles with a size of tens of nanometers. [...]
2023 - 10 p. - Published in : CrystEngComm 25 (2023) 4345-4354 Fulltext: PDF;
3.
Modeling Scintillation Kinetics and Coincidence Time Resolution in Heterostructured Scintillators / Pagano, Fiammetta (CERN ; Milan Bicocca U.) ; Kratochwil, Nicolaus (CERN) ; Martinazzoli, Loris (CERN ; Milan Bicocca U.) ; Lowis, Carsten (CERN ; Milan Bicocca U.) ; Paganoni, Marco (CERN ; Milan Bicocca U.) ; PIzzichemi, Marco (CERN ; Milan Bicocca U.) ; Auffray, Etiennette (CERN)
In the search for new materials and technologies to push the timing performances of time-of-flight positron emission tomography (TOF-PET) detectors, it is important to have a model capable of predicting the coincidence time resolution (CTR) of the system to be implemented. While for bulk standard scintillators, a model that takes into account the intrinsic properties of the material (and the characteristics of the photodetector) is already well established, it has never been experimentally validated for composite structures. [...]
2023 - 8 p. - Published in : IEEE Trans. Nucl. Sci. 70 (2023) 2630-2637 Fulltext: PDF;
4.
Concept development of an on-chip PET system / Clement, Christoph (Bern U.) ; Birindelli, Gabriele (Bern U.) ; Pizzichemi, Marco (CERN ; Milan Bicocca U.) ; Pagano, Fiammetta (CERN ; Milan Bicocca U.) ; Julio, Marianna Kruithof‑De (Bern U.) ; Ziegler, Sibylle (LMU Munich (main)) ; Rominger, Axel (Bern U.) ; Aufray, Etiennette (CERN) ; Shi, Kuangyu (Bern U.)
Organs-on-Chips (OOCs), microdevices mimicking in vivo organs, find growing applications in disease modeling and drug discovery. With the increasing number of uses comes a strong demand for imaging capabilities of OOCs as monitoring physiologic processes within OOCs is vital for the continuous improvement of this technology. [...]
2022 - 24 p. - Published in : EJNMMI Physics 9 (2022) 38 Fulltext: PDF;
5.
Image Reconstruction Analysis for Positron Emission Tomography With Heterostructured Scintillators / Mohr, Philipp (CERN ; FH Aachen (main) ; U. Groningen (main)) ; Efthimiou, Nikos (Penn State U.) ; Pagano, Fiammetta (CERN ; Milan Bicocca U.) ; Kratochwil, Nicolaus (CERN) ; Pizzichemi, Marco (CERN ; Milan Bicocca U.) ; Tsoumpas, Charalampos (U. Groningen (main) ; U. Leeds (main)) ; Auffray, Etiennette (CERN) ; Ziemons, Karl (FH Aachen (main))
The concept of structure engineering has been proposed for exploring the next generation of radiation detectors with improved performance. A TOF-PET geometry with heterostructured scintillators with a pixel size of $3.0 \times 3.1 \times15$ mm$^3$ was simulated using Monte Carlo. [...]
2023 - 11 p. - Published in : IEEE Trans. Rad. Plasma Med. Sci. 7 (2023) 41-51 Fulltext: PDF;
6.
Timing performance of lead halide perovskite nanoscintillators embedded in a polystyrene matrix / Děcká, Kateřina (Prague, Tech. U. ; Prague, Inst. Phys.) ; Pagano, Fiammetta (CERN ; Milan Bicocca U.) ; Frank, Isabel (CERN ; LMU Munich (main)) ; Kratochwil, Nicolaus (CERN) ; Mihóková, Eva (Prague, Tech. U. ; Prague, Inst. Phys.) ; Auffray, Etiennette (CERN) ; Čuba, Václav (Prague, Tech. U.)
Nanomaterials like CsPbBr$_3$, benefiting from quantum confinement effects to feature ultra-fast decay time and tunable emission, are paving the way for the next generation of fast timing detectors. However, an ongoing challenge is to exploit their favorable properties in a full detector, given their size and instability. [...]
2022 - 8 p. - Published in : J. Mater. Chem. 10 (2022) 12836-12843 Fulltext: PDF;
7.
A new method to characterize low stopping power and ultra-fast scintillators using pulsed X-rays / Pagano, Fiammetta (CERN ; Milan Bicocca U.) ; Kratochwil, Nicolaus (CERN ; Vienna U.) ; Frank, Isabel (CERN ; Munich U.) ; Gundacker, Stefan (CERN) ; Paganoni, Marco (CERN ; Milan Bicocca U.) ; Pizzichemi, Marco (CERN ; Milan Bicocca U.) ; Salomoni, Matteo (CERN) ; Auffray, Etiennette (CERN)
The demand for detectors with a time resolution below 100 ps is at the center of research in different fields, from high energy physics to medical imaging. In recent years, interest has grown in nanomaterials that, benefiting from quantum confinement effects, can feature ultra-fast scintillation kinetics and tunable emission. [...]
2022 - 11 p. - Published in : Front. Phys. 10 (2022) 1021787 Fulltext: PDF;
8.
New Technologies for Time-of-Flight PET: Heterostructured Scintillators / Pagano, Fiammetta (speaker) ((Universita & INFN, Milano-Bicocca (IT) and CERN)
Fiammetta Pagano1,2, Nicolaus Kratochwil1, Matteo Salomoni1, Loris Martinazzoli1,2, Marco Paganoni2,1, Marco Pizzichemi1,2, Etiennette Auffray1 1 European Organization for Nuclear Research (CERN). Geneva, Switzerland 2University of Milano-Bicocca. [...]
2022 - 1406. KT Seminars; EARLY-CAREER RESEARCHERS IN MEDICAL APPLICATIONS @ CERN – SHORT TALKS External links: Talk details; Event details In : EARLY-CAREER RESEARCHERS IN MEDICAL APPLICATIONS @ CERN – SHORT TALKS
9.
Advances in heterostructured scintillators: toward a new generation of detectors for TOF-PET / Pagano, Fiammetta (CERN ; Milan Bicocca U.) ; Kratochwil, Nicolaus (CERN ; Vienna U.) ; Salomoni, Matteo (CERN) ; Pizzichemi, Marco (CERN ; Milan Bicocca U.) ; Paganoni, Marco (CERN ; Milan Bicocca U.) ; Auffray, Etiennette (CERN)
Objective. Time-of-flight-positron emission tomography would highly benefit from a coincidence time resolution (CTR) below 100 ps: improvement in image quality and patient workflow, and reduction of delivered dose are among them. [...]
2022 - 12 p. - Published in : Phys. Med. Biol. 67 (2022) 135010 Fulltext: PDF;
10.
Sub-100-picosecond time resolution from undoped and Li-doped two-dimensional perovskite scintillators / Cala', Roberto (CERN) ; Frank, Isabel (CERN) ; Pagano, Fiammetta (CERN) ; Maddalena, Francesco (Unlisted, SG) ; Dang, Cuong (Unlisted, SG) ; Birowosuto, Muhammad Danang (Unlisted, PL) ; Auffray, Etiennette (CERN)
Fast hybrid organic–inorganic two-dimensional (2D) perovskite scintillators with high light yield are measured for their scintillating properties. With a light yield of 17 300 ± 2140 photons/MeV, undoped PEA2PbBr4 crystals already exhibit 100 ± 4 ps coincidence time resolution (CTR) at 511 keV excitation. [...]
2022 - 5 p. - Published in : Appl. Phys. Lett. 120 (2022) 241901

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