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Investigating the robustness of ion beam therapy treatment plans to uncertainties in biological treatment parameters / Boehlen, T T (CERN ; Stockholm U. ; Karolinska Inst., Stockholm) ; Brons, S (Ion Beam Therapy Ctr, Heidelberg) ; Dosanjh, M (CERN) ; Ferrari, A (CERN) ; Fossati, P (CNAO, Pavia, Italy. ; U. Milan ; Eur. Inst. Oncol., Milan) ; Haberer, T (Ion Beam Therapy Ctr, Heidelberg) ; Mairani, A (Fdn CNAO, Pavia) ; Patera, V (U. Rome La Sapienza (main) ; Frascati)
Uncertainties in determining clinically used relative biological effectiveness (RBE) values for ion beam therapy carry the risk of absolute and relative misestimations of RBE-weighted doses for clinical scenarios. This study assesses the consequences of hypothetical misestimations of input parameters to the RBE modelling for carbon ion treatment plans by a variational approach. [...]
2012 - Published in : Phys. Med. Biol. 57 (2012) 7983-8004

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Extended calibration range for prompt photon emission in ion beam irradiation / Bellini, F. (Rome U. ; INFN, Rome) ; Boehlen, T.T. (CERN) ; Chin, M.P.W. (CERN) ; Collamati, F. (INFN, Rome ; Rome U.) ; De Lucia, E. (Frascati) ; Faccini, R. (INFN, Rome ; Rome U.) ; Ferrari, A. (CERN) ; Lanza, L. (INFN, Rome ; Rome U.) ; Mancini-Terraciano, C. (Rome III U. ; CERN) ; Marafini, M. (Enrico Fermi Ctr., Rome ; INFN, Rome) et al.
Monitoring the dose delivered during proton and carbon ion therapy is still a matter of research. Among the possible solutions, several exploit the measurement of the single photon emission from nuclear decays induced by the irradiation. [...]
arXiv:1307.5689.- 2014-05-01 - 5 p. - Published in : Nucl. Instrum. Methods Phys. Res., A 745 (2014) 114-118 Elsevier Open Access article: PDF; Fulltext: PDF; External link: Preprint

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Performance of upstream interaction region detectors for the FIRST experiment at GSI / Abou-Haidar, Z (CNA, Seville) ; Agodi, C (INFN, LNS) ; Alvarez, M A G (CNA, Seville) ; Anelli, M (INFN, Milan) ; Aumann, T (Darmstadt, GSI) ; Battistoni, G (INFN, Milan) ; Bocci, A (CNA, Seville) ; Bohlen, T T (CERN ; Karolinska Hospital, Stockholm ; Stockholm U.) ; Boudard, A (IRFU, SPhN, Saclay) ; Brunetti, A (INFN, Cagliari ; Sassari U.) et al.
The FIRST (Fragmentation of Ions Relevant for Space and Therapy) experiment at GSI has been designed to study carbon fragmentation, measuring (12)C double differential cross sections (- (2)I /- - E) for different beam energies between 100 and 1000 MeV/u. The experimental setup integrates newly designed detectors in the, so called, Interaction Region around the graphite target. [...]
2012 - 15 p. - Published in : JINST 7 (2012) P02006 IOP Open Access article: PDF;

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Describing Compton scattering and two-quanta positron annihilation based on Compton profiles: Two models suited for the Monte Carlo method / Bohlen, TT (CERN ; Stockholm U.) ; Ferrari, A (CERN) ; Patera, V (Rome U., La Sapienza, Dip. di Energetica ; Frascati) ; Sala, P R (INFN, Milan)
An accurate description of the basic physics processes of Compton scattering and positron annihilation in matter requires the consideration of atomic shell structure effects and, in specific, the momentum distributions of the atomic electrons. Two algorithms which model Compton scattering and two-quanta positron annihilation at rest accounting for shell structure effects are proposed. [...]
2012 - Published in : JINST 7 (2012) P07018 IOP Open Access article: PDF;

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