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Medical activities in CLEAR: studies towards radiotherapy using Very High Energy Electrons (VHEE) in the FLASH regime
/ Corsini, Roberto (CERN) ; Malyzhenkov, Alexander (CERN) ; Gilardi, Antonio (Naples U. ; INFN, Naples) ; Aksoy, Avni (CERN) ; Robertson, Cameron (Oxford U.) ; Bateman, Joseph (Oxford U.) ; Dosanjh, Manjit (CERN) ; Korysko, Pierre (Oxford U.) ; Rieker, Vilde (CERN) ; Farabolini, Wilfrid (CERN)
Given the present availability of high-gradient accelerator technology for compact and cost-effective electron linacs in the 100-200 MeV energy range, the interest for Very High Energy Electron (VHEE) radiotherapy (RT) for cancer treatment recently reached an all-time high. Particular significance is assumed by the Ultra-High Dose Rate (UHDR) regime where the so-called FLASH biological effect takes place, in which cancer cells are damaged while healthy tissue is largely spared. [...]
2024 - 4 p.
- Published in : JACoW LINAC 2024 (2024) THPB018
Fulltext: PDF;
In : 32nd Linear Accelerator Conference (LINAC 2024), Chicago, Illinois, United States, 25 - 30 Aug 2024, pp.THPB018
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Active dosimetry for VHEE FLASH radiotherapy using beam profile monitors and charge measurements
/ Rieker, Vilde F (CERN ; Oslo U.) ; Corsini, Roberto (CERN) ; Stapnes, Steinar (CERN) ; Adli, Erik (Oslo U.) ; Farabolini, Wilfrid (CERN) ; Grilj, Veljko (SUBATECH, Nantes) ; Sjobak, Kyrre N (Oslo U.) ; Wroe, Laurence M (CERN) ; Aksoy, Avni (CERN ; Ankara U.) ; Robertson, Cameron S (Oxford U.) et al.
The discovery of the FLASH effect has revealed a high potential for treating cancer more efficiently by sparing
healthy tissue. The surge in related medical research activities over the last couple of years has triggered a
demand for technology with the capability of generating and measuring ionizing radiation at ultra-high doserates (UHDR). [...]
2024 - 12 p.
- Published in : Nucl. Instrum. Methods Phys. Res., A 1069 (2024) 169845
Fulltext: PDF;
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Bubble-beam accelerators: breaking the paradigm
/ Malyzhenkov, Alexander (CERN) ; Latina, Andrea (CERN) ; Dyks, Luke (CERN) ; Corsini, Roberto (CERN) ; Farabolini, Wilfrid (CERN) ; Aksoy, Avni (CERN ; Ankara U.) ; Korysko, Pierre (JAI, UK ; CERN) ; Burrows, Philip (JAI, UK) ; Tranchedone, Lorenzo (JAI, UK ; CERN)
Most particle accelerators utilize beams with a charge density concentrated in the center of the bunch in real 3-dimensional space and the 6-dimensional phase space. In this work, by enhancing the space-charge forces in the photo-cathode injector of the Compact Linear Electron Accelerator for Research (CLEAR) at CERN, we produce electron bunches with a “bubble-like” shape, with a charge density mostly concentrated on the outside shell. [...]
2024 - 4 p.
- Published in : JACoW IPAC 2024 (2024) WEPC03
Fulltext: PDF;
In : 15th International Particle Accelerator Conference (IPAC 2024), Nashville, TN, United States, 19 - 24 May 2024, pp.WEPC03
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5.
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Interim report for the International Muon Collider Collaboration
/ Accettura, Carlotta
The International Muon Collider Collaboration (IMCC) [1] was established in 2020 following the recommendations of the European Strategy for Particle Physics (ESPP) and the implementation of the European Strategy for Particle Physics-Accelerator R&D Roadmap by the Laboratory Directors Group [2], [...]
arXiv:2407.12450 ; CERN-2024-002
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Geneva : CERN, 2024-09-30 - 150.
(CERN Yellow Reports: Monographs ; 2/2024)
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e-book
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Application of beam-based alignment to the CLEAR facility
/ Aksoy, Avni (Ankara U. ; CERN) ; Malyzhenkov, Alexander (CERN) ; Latina, Andrea (CERN) ; Korysko, Pierre (Oxford U. ; CERN) ; Corsini, Roberto (CERN) ; Farabolini, Wilfrid (CERN)
The CERN Linear Electron Accelerator for Research (CLEAR) has been operating since 2017 as a user facility providing beams for a large variety of experiments. Its RF photocathode-based linear accelerator can accelerate electrons up to 220 MeV with a bunch charge of 0.1-1.5nC with single or up to 150 bunches per train. [...]
2023 - 4 p.
- Published in : JACoW IPAC 2023 (2023) WEPL025
Fulltext: PDF;
In : 14th International Particle Accelerator Conference (IPAC 2023), Venice, Italy, 7 - 12 May 2023, pp.WEPL025
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The CompactLight Design Study
/ D'Auria, G (Sincrotrone Trieste) ; Adli, E (Oslo U.) ; Aicheler, M (Helsinki Inst. of Phys.) ; Aksoy, A (Ankara U.) ; Alesini, D (Frascati) ; Apsimon, R (Daresbury ; Lancaster U.) ; Arnsberg, J (KIT, Karlsruhe) ; Auchettl, R (ASP, Melbourne) ; Bainbridge, A (Daresbury) ; Balazs, K (CERN) et al.
CompactLight is a Design Study funded by the European Union under theHorizon 2020 research and innovation funding programme, with Grant Agreement No. 777431.CompactLight was conducted by an International Collaboration of 23 internationallaboratories and academic institutions, three private companies, and five third parties.The project, which started in January 2018 with a duration of 48 months, aimed to designan innovative, compact, and cost-effective hard X-ray FEL facility complemented by asoft X-ray source to pave the road for future compact accelerator-based facilities. [...]
2024 - 208 p.
- Published in : Eur. Phys. J. Spec. Top. 233 (2024) 1-208
Fulltext: PDF;
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Implementation of the beam-loading effect in the tracking code RF-track based on a power-diffusive model
/ Olivares Herrador, Javier (CERN ; Valencia U., IFIC) ; Latina, Andrea (CERN) ; Aksoy, Avni (CERN ; Ankara U.) ; Fuster Martínez, Nuria (Valencia U., IFIC) ; Gimeno, Benito (Valencia U., IFIC) ; Esperante, Daniel (Valencia U., IFIC ; U. Sevilla, Dept. Electron. Eng.)
The need to achieve high energies in particle accelerators is leading to the development of new accelerator technologies, resulting in higher beam intensities and more compact devices with stronger accelerating fields. In such scenarios, Beam Loading effects occur and a intensitydependent gradient reduction affects the accelerated beam as a consequence of its interaction with the surrounding cavity. [...]
2024 - 11 p.
- Published in : Front. Phys. 12 (2024) 1348042
Fulltext: PDF;
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Electron beam studies on a beam position monitor based on Cherenkov diffraction radiation
/ Pakuza, Collette (JAI, UK) ; Malyzhenkov, Alexander (CERN) ; Schloegelhofer, Andreas (CERN) ; Aksoy, Avni (CERN) ; Spear, Bethany (JAI, UK) ; Senes, Eugenio (CERN) ; Lasocha, Kacper (CERN) ; Wendt, Manfred (CERN) ; Krupa, Michal (CERN) ; Chritin, Nicolas (CERN) et al.
A beam position monitor based on Cherenkov diffraction radiation (ChDR BPM) is currently under investigation to disentangle the electromagnetic field of an electron bunch from that of a proton bunch travelling together in time and space in the beam-line of the AWAKE plasma acceleration experiment at CERN. The signals from a horizontal pair of ChDR BPM radiators have been studied under a variety of beam conditions at the CLEAR electron beam test facility. [...]
2023 - 4 p.
- Published in : JACoW IPAC 2023 (2023) THPL146
Fulltext: PDF;
In : 14th International Particle Accelerator Conference (IPAC 2023), Venice, Italy, 7 - 12 May 2023, pp.THPL146
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A start-to-end optimisation of CLEAR for an inverse Compton scattering experiment, using RF-Track
/ Musat, Vlad (CERN ; JAI, UK) ; Latina, Andrea (CERN) ; Malyzhenkov, Alexander (CERN) ; Aksoy, Avni (CERN)
The CERN Linear Electron Accelerator for Research (CLEAR) has been operating since 2017 as a user facility providing beams for various experiments. We created a start-to-end model of the CLEAR setup in RF-Track, aiming to optimise the CLEAR accelerator as a driver for an X-ray source based on inverse-Compton scattering. [...]
2023 - 4 p.
- Published in : JACoW IPAC 2023 (2023) TUPL180
Fulltext: PDF;
In : 14th International Particle Accelerator Conference (IPAC 2023), Venice, Italy, 7 - 12 May 2023, pp.TUPL180
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