002804342 001__ 2804342
002804342 003__ SzGeCERN
002804342 005__ 20221031171231.0
002804342 0247_ $$2DOI$$a10.1186/s13073-020-0713-z
002804342 0248_ $$aoai:cds.cern.ch:2804342$$pcerncds:CERN
002804342 035__ $$9https://inspirehep.net/api/oai2d$$aoai:inspirehep.net:2018454$$d2022-03-18T12:13:31Z$$h2022-03-19T08:28:46Z$$mmarcxml
002804342 035__ $$9Inspire$$a2018454
002804342 041__ $$aeng
002804342 100__ $$aAarestrup, F M$$uDenmark, Tech. U.
002804342 245__ $$9submitter$$aTowards a European health research and innovation cloud (HRIC)
002804342 260__ $$c2020
002804342 300__ $$a14 p
002804342 520__ $$9submitter$$aThe European Union (EU) initiative on the Digital Transformation of Health and Care (Digicare) aims to provide the
conditions necessary for building a secure, flexible, and decentralized digital health infrastructure. Creating a European
Health Research and Innovation Cloud (HRIC) within this environment should enable data sharing and analysis for
health research across the EU, in compliance with data protection legislation while preserving the full trust of the
participants. Such a HRIC should learn from and build on existing data infrastructures, integrate best practices, and
focus on the concrete needs of the community in terms of technologies, governance, management, regulation, and
ethics requirements. Here, we describe the vision and expected benefits of digital data sharing in health research
activities and present a roadmap that fosters the opportunities while answering the challenges of implementing a
HRIC. For this, we put forward five specific recommendations and action points to ensure that a European HRIC: i) is
built on established standards and guidelines, providing cloud technologies through an open and decentralized
infrastructure; ii) is developed and certified to the highest standards of interoperability and data security that can be
trusted by all stakeholders; iii) is supported by a robust ethical and legal framework that is compliant with the EU
General Data Protection Regulation (GDPR); iv) establishes a proper environment for the training of new generations of
data and medical scientists; and v) stimulates research and innovation in transnational collaborations through public
and private initiatives and partnerships funded by the EU through Horizon 2020 and Horizon Europe.
002804342 540__ $$3publication$$aCC BY 4.0$$uhttp://creativecommons.org/licenses/by/4.0/
002804342 542__ $$3publication$$dThe Author(s)$$g2020
002804342 65017 $$2INSPIRE$$aHealth Physics and Radiation Effects
002804342 690C_ $$aARTICLE
002804342 690C_ $$aCERN
002804342 700__ $$aAlbeyatti, A$$uMedicalchain, London$$uNHS, UK
002804342 700__ $$aArmitage, W J$$uBristol U.
002804342 700__ $$aAuffray, C$$uEISBM, Vourles
002804342 700__ $$aAugello, L$$uARIA, Milan
002804342 700__ $$aBalling, R$$uLuxembourg U.
002804342 700__ $$aBenhabiles, N$$uU. Paris-Saclay
002804342 700__ $$aBertolini, G$$uBergamo U.
002804342 700__ $$aBjaalie, J G$$uOslo U.
002804342 700__ $$aBlack, M$$uUlster U.
002804342 700__ $$aBlomberg, [email protected]$$uELIXIR, Welcome Genome Campus, Cambridge
002804342 700__ $$aBogaert, P$$uTilburg U.
002804342 700__ $$aBubak, M$$uAGH-UST, Cracow
002804342 700__ $$aClaerhout, B$$uGent U.
002804342 700__ $$aClarke, L$$uUnlisted, GB
002804342 700__ $$aDe Meulder, B$$uEISBM, Vourles
002804342 700__ $$aD'Errico, G$$uFondazione Toscana Life Sciences, Siena
002804342 700__ $$aDi Meglio, A$$uCERN
002804342 700__ $$aForgo, N$$uVienna U.
002804342 700__ $$aGans-Combe, C$$uINSEEC School of Business & Economics, Paris
002804342 700__ $$aGray, A E$$uPwC, Oslo
002804342 700__ $$aGut, I$$uCtr. Genomic Regulations, Barcelona
002804342 700__ $$aGyllenberg, A$$uKarolinska Hospital, Stockholm
002804342 700__ $$aHemmrich-Stanisak, G$$uKiel U.
002804342 700__ $$aHjorth, L$$uLund U.
002804342 700__ $$aIoannidis, Y$$uAthens U.
002804342 700__ $$aJarmalaite, S$$uUnlisted, LT
002804342 700__ $$aKel, A$$ugeneXplain GmbH, Wolfenbüttel
002804342 700__ $$aKherif, F$$uCtr. Hosp. Univ. Vaudois, Lausanne
002804342 700__ $$aKorbel, J [email protected]$$uEMBL, Heidelberg
002804342 700__ $$aLarue, C$$uIntegrated Biobank of Luxembourg
002804342 700__ $$aLaszlo, M
002804342 700__ $$aMaas, A$$uAntwerp U.
002804342 700__ $$aMagalhaes, L$$uClinerion Ltd., Basel
002804342 700__ $$aManneh-Vangramberen, I$$uEuropean Cancer Patient Coalition, Brussels
002804342 700__ $$aMorley-Fletcher, E$$uLynkeus, Rome
002804342 700__ $$aOhmann, C$$uHeinrich Heine U., Dusseldorf
002804342 700__ $$aOksvold, P$$uRoyal Inst. Tech., Stockholm
002804342 700__ $$aOxtoby, N P$$uU. Coll. London
002804342 700__ $$aPerseil, I$$uInst. Natl. Santé Rech. Méd., Paris
002804342 700__ $$aPezoulas, V$$uIoannina U.
002804342 700__ $$aRiess, O$$uInst. Med. Gen. Appl. Genomics, Tübingen
002804342 700__ $$aRiper, H$$uVrije U., Amsterdam
002804342 700__ $$aRoca, J$$uBarcelona U.
002804342 700__ $$aRosenstiel, P$$uKiel U.
002804342 700__ $$aSabatier, P$$uU. Grenoble Alpes
002804342 700__ $$aSanz, F$$uPompeu Fabra U.
002804342 700__ $$aTayeb, M$$uUnlisted, GB
002804342 700__ $$aThomassen, G$$uOslo U.
002804342 700__ $$aVan Bussel, J$$uSci. Inst. Public Health, Brussels
002804342 700__ $$aVan den Bulcke, M$$uSci. Inst. Public Health, Brussels
002804342 700__ $$aVan Oyen, H$$uAGH-UST, Cracow
002804342 773__ $$c18$$n1$$pGenome Medicine$$v12$$y2020
002804342 960__ $$a13
002804342 980__ $$aARTICLE