Zymeworks Inc.

Zymeworks Inc.

Biotechnology Research

Vancouver, BC 27,849 followers

Developing novel medicines for patients with difficult-to-treat cancers and other serious diseases.

About us

Zymeworks is a global clinical-stage biotechnology company committed to the discovery, development, and commercialization of novel, multifunctional biotherapeutics. Zymeworks’ mission is to make a meaningful difference in the lives of people impacted by difficult-to-treat cancers and other diseases. The Company’s complementary therapeutic platforms and fully integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly differentiated antibody-based therapeutic candidates. Zymeworks engineered and developed zanidatamab, a HER2-targeted bispecific antibody using the Company’s proprietary Azymetric™ technology. Zymeworks has entered into separate agreements with BeiGene, Ltd. (BeiGene) and Jazz Pharmaceuticals Ireland Limited (Jazz), granting each exclusive rights to develop and commercialize zanidatamab in different territories. Zanidatamab is currently being evaluated in multiple global clinical trials as a potential best-in-class treatment for patients with HER2-expressing cancers. A Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) seeking accelerated approval for zanidatamab as a treatment for previously-treated, unresectable, locally advanced, or metastatic HER2-positive biliary tract cancer (BTC) has been accepted and granted Priority Review. A BLA has also been accepted for review by the Center for Drug Evaluation (CDE) of the National Medical Products Administration (NMPA) in China. If approved, zanidatamab would be the first HER2-targeted treatment specifically approved for BTC in the U.S. and China. Zymeworks is advancing a robust pipeline of wholly-owned product candidates based on its experience and capabilities in both antibody-drug conjugates and multispecific antibodies. Phase 1 studies for ZW171 and ZW191 are now actively recruiting at sites worldwide. Additionally, Zymeworks’ therapeutic platforms have been further leveraged through strategic partnerships.

Website
http://www.zymeworks.com
Industry
Biotechnology Research
Company size
201-500 employees
Headquarters
Vancouver, BC
Type
Public Company
Founded
2003
Specialties
antibody therapeutics, bispecific antibodies, effector function modulation, ADC, Breast Cancer, Gastric Cancer, protein engineering, Immune redirection, and Biliary Tract Cancer

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Employees at Zymeworks Inc.

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Funding

Zymeworks Inc. 15 total rounds

Last Round

Post IPO equity

US$ 37.9M

Investors

EcoR1 Capital
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