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AZI1

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AZI1
Identifikatori
AliasiCEP131
Vanjski ID-jeviOMIM: 613479 MGI: 107440 HomoloGene: 7638 GeneCards: CEP131
Lokacija gena (čovjek)
Hromosom 17 (čovjek)
Hrom.Hromosom 17 (čovjek)[1]
Hromosom 17 (čovjek)
Genomska lokacija za AZI1
Genomska lokacija za AZI1
Bend17q25.3Početak81,189,593 bp[1]
Kraj81,222,999 bp[1]
Lokacija gena (miš)
Hromosom 11 (miš)
Hrom.Hromosom 11 (miš)[2]
Hromosom 11 (miš)
Genomska lokacija za AZI1
Genomska lokacija za AZI1
Bend11|11 E2Početak120,064,430 bp[2]
Kraj120,086,827 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija protein homodimerization activity
GO:0001948, GO:0016582 vezivanje za proteine
GO:0032403 protein-containing complex binding
Ćelijska komponenta citoplazma
citosol
centrosom
projekcija ćelije
intracellular membrane-bounded organelle
microtubule cytoskeleton
centriolar satellite
centar organizacije mikrotubula
Akrozom
intercellular bridge
citoskelet
GO:0016023 citoplazmatska vezikula
ciliary transition zone
ciliary basal body
Treplja
Biološki proces positive regulation of intracellular protein transport
Ćelijska diferencijacija
regulation of centrosome duplication
multicellular organism development
intraciliary transport involved in cilium assembly
cell projection organization
G2/M transition of mitotic cell cycle
Spermatogeneza
positive regulation of cell population proliferation
protein localization to centrosome
ćelijski ciklus
ciliary basal body-plasma membrane docking
regulation of G2/M transition of mitotic cell cycle
cilium assembly
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001009811
NM_014984
NM_001319228
NM_001319229

NM_009734

RefSeq (bjelančevina)

NP_001009811
NP_001306157
NP_001306158
NP_055799

NP_033864
NP_001390635
NP_001390663

Lokacija (UCSC)Chr 17: 81.19 – 81.22 MbChr 11: 120.06 – 120.09 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

5-azacitidin-inducirani protein 1 jest protein koji je kod ljudi kodiran genom AZI1.[5][6][7][8]

Dužina polipeptidnog lanca je 1.083 aminokiseline, sa molekulskom težinom od 122.149.[9]

Aminokiselinska sekvenca

Simboli
1020304050
MKGTRAIGSVPERSPAGVDLSLTGLPPPVSRRPGSAATTKPIVRSVSVVT
GSEQKRKVLEATGPGGSQAINNLRRSNSTTQVSQPRSGSPRPTEPTDFLM
LFEGSPSGKKRPASLSTAPSEKGATWNVLDDQPRGFTLPSNARSSSALDS
PAGPRRKECTVALAPNFTANNRSNKGAVGNCVTTMVHNRYTPSERAPPLK
SSNQTAPSLNNIIKAATCEGSESSGFGKLPKNVSSATHSARNNTGGSTGL
PRRKEVTEEEAERFIHQVNQATVTIQRWYRHQVQRRGAGAARLEHLLQAK
REEQRQRSGEGTLLDLHQQKEAARRKAREEKARQARRAAIQELQQKRALR
AQKASTAERGPPENPRETRVPGMRQPAQELSPTPGGTAHQALKANNTGGG
LPAAGPGDRCLPTSDSSPEPQQPPEDRTQDVLAQDAAGDNLEMMAPSRGS
AKSRGPLEELLHTLQLLEKEPDVLPRPRTHHRGRYAWASEVTTEDDASSL
TADNLEKFGKLSAFPEPPEDGTLLSEAKLQSIMSFLDEMEKSGQDQLDSQ
QEGWVPEAGPGPLELGSEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRDL
TARRVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEA
VVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKWISEKT
KKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAELLQSDERASQRCLR
QAEELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEV
AEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERR
HQMELNTLKQQLELERQAWEAGRTRKEEAWLLNREQELREEIRKGRDKEI
ELVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQER
CSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVI
RQEFEDRLAASEEETRQAKAELATLQARQQLELEEVHRRVKTALARKEEA
VSSLRTQHEAAVKRADHLEELLEQHRRPTPSTK

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000141577 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039781 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
  6. ^ Aoto H, Miyake Y, Nakamura M, Tajima S (1997). "Genomic organization of the mouse AZ1 gene that encodes the protein localized to preacrosomes of spermatids". Genomics. 40 (1): 138–41. doi:10.1006/geno.1996.4546. PMID 9070930.
  7. ^ Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, Mann M (2003). "Proteomic characterization of the human centrosome by protein correlation profiling". Nature. 426 (6966): 570–4. doi:10.1038/nature02166. PMID 14654843. S2CID 4427303.
  8. ^ "Entrez Gene: AZI1 5-azacytidine induced 1".
  9. ^ "UniProt, Q9UPN4". Pristupljeno 12. 9. 2017.

Vanjski linkovi

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Dopunska literatura

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