Evidence for interstate transmission and increase in prevalence of bovine group B rotavirus strains with a novel VP7 genotype among diarrhoeic calves in Eastern and Northern states of India

Epidemiol Infect. 2007 Nov;135(8):1324-30. doi: 10.1017/S0950268806007813. Epub 2007 Feb 12.

Abstract

During a surveillance study (2003-2005) in a cattle market in Kolkata city, state of West Bengal, Eastern India, 34 (13.0%) of 260 calves with diarrhoea were positive for group B rotaviruses (GBR) by RNA electrophoresis in polyacrylamide gels. Analysis of the partial VP7 gene sequence of 28 of the 34 GBR strains revealed maximum identities (97.7-99.5% at nucleotide level and 97.8-100% at amino-acid level) with the novel bovine GBR 'Kolkata strains' reported in an earlier surveillance study (1.5%, n=192, 2001-2002) from the same cattle market, and shared low identities of 73.7-78.9% and 80.8-89.6%; 62.6-66.2% and 59.8-65.4%; 58.9-62.2% and 48.6-54.9% at nucleotide and amino-acid level with other bovine, human, and murine GBR. The GBR-infected calves were traced to districts in neighbouring states of West Bengal. Therefore, the present study reports a rapid increase in prevalence (13.0% in 2003-2005 against 1.5% in 2001-2002) of novel GBR strains among calves with diarrhoea, and provides evidence for interstate transmission of GBR.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antigens, Viral / genetics*
  • Capsid Proteins / genetics*
  • Cattle
  • Cattle Diseases / epidemiology*
  • Cattle Diseases / transmission*
  • Cattle Diseases / virology
  • Cluster Analysis
  • Diarrhea / epidemiology
  • Diarrhea / veterinary*
  • Diarrhea / virology
  • Electrophoresis, Polyacrylamide Gel
  • Feces / virology
  • Genotype
  • India
  • Molecular Epidemiology
  • Phylogeny
  • Prevalence
  • RNA, Viral / isolation & purification
  • Rotavirus / classification*
  • Rotavirus / genetics
  • Rotavirus / isolation & purification
  • Rotavirus Infections / epidemiology
  • Rotavirus Infections / transmission
  • Rotavirus Infections / veterinary*
  • Rotavirus Infections / virology
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid

Substances

  • Antigens, Viral
  • Capsid Proteins
  • RNA, Viral
  • VP7 protein, Rotavirus