Abstract
The authors describe a fast method for calculating left ventricle (LV) mass and volumes from multiplanar magnetic resonance (MR) images. Mathematic models were fitted to a small number of user-selected guide points in 15 healthy volunteers, 13 patients after myocardial infarction, and a canine model of mitral regurgitation in eight dogs. Errors between model and manual contours were small (LV mass, 1.8 g +/- 4.9 [mean +/- SD]; end-diastolic volume, 2.2 mL +/- 4.6; end-systolic volume, 2.3 mL +/- 3.8). Estimates of global function could be obtained in 6 minutes, a time saving of 5-10 times over estimates with manual contouring.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Algorithms
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Animals
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Blood Flow Velocity / physiology
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Cardiac Output / physiology
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Cardiac Volume / physiology*
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Diastole
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Disease Models, Animal
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Dogs
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Female
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Finite Element Analysis
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Heart Ventricles / anatomy & histology*
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Humans
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Image Processing, Computer-Assisted / methods*
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Magnetic Resonance Imaging, Cine / methods*
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Male
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Mitral Valve Insufficiency / pathology
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Mitral Valve Insufficiency / physiopathology
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Models, Cardiovascular
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Myocardial Infarction / pathology
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Myocardial Infarction / physiopathology
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Stroke Volume / physiology
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Systole
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Time Factors
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Ventricular Function, Left / physiology*