Sheffield Institute for Translational Neuroscience SITraN is an essential development in the fight against motor neurone disease, other common neurodegenerative disorders, stroke and neuroinflammatory conditions. You are here Home Sheffield Institute for Translational Neuroscience Photo of Queen Elizabeth II visiting SITraN in 2010 About SITraN Our impact Our research Study with us Facilities News 20 June 2024 New clue in understanding increased Alzheimer’s risk Scientists have discovered a new piece of the puzzle in understanding why some people are more susceptible to Alzheimer’s disease. 20 June 2024 Comment: A devastating setback for MND research: Why NICE needs to reconsider its approach to tofersen Professor Dame Pamela Shaw, Director of the Sheffield Institute for Translational Neuroscience, discusses NICE's refusal to classify the MND drug tofersen, as a treatment for a highly specialised condition, rather than just a standard drug. 13 May 2024 Sheffield team is sole UK recipient to be awarded share of $5 million global funding to fight motor neuron disease A team of researchers from the University of Sheffield have been awarded a share of a prestigious grant to fight MND. 9 May 2024 New psychological therapy shows promise in improving quality of life for people living with MND Therapy can significantly improve quality of life for people living with MND when delivered alongside usual care, a pioneering study led by the University of Sheffield has shown. View all SITraN news