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Search life-sciences literature (45,104,206 articles, preprints and more)

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Molecular landscape of ERBB2 alterations in 3000 advanced NSCLC patients.
Hong L, Patel S, Drusbosky LM, Xiong Y, Chen R, Geng R, Heeke S, Nilsson M, Wu J, Heymach JV, Wang Y, Zhang J, Le X
NPJ Precis Oncol, 8(1):217, 01 Oct 2024
Cited by: 0 articles | PMID: 39354054 | PMCID: PMC11445497
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YAP1 Status Defines Two Intrinsic Subtypes of LCNEC with Distinct Molecular Features and Therapeutic Vulnerabilities.
Stewart CA, Diao L, Xi Y, Wang R, Ramkumar K, Serrano AG, Tanimoto A, Rodriguez BL, Morris BB, Shen L, Zhang B, Yang Y, Hamad SH, Cardnell RJ, Duarte A, Sahu M, Novegil VY, Weissman BE, Frumovitz M, [...] Gay CM
Clin Cancer Res, 30(20):4743-4754, 01 Oct 2024
Cited by: 0 articles | PMID: 39150543
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Machine learning enabled classification of lung cancer cell lines co-cultured with fibroblasts with lightweight convolutional neural network for initial diagnosis.
Germain A, Sabol A, Chavali A, Fitzwilliams G, Cooper A, Khuon S, Green B, Kong C, Minna J, Kim YT
J Biomed Sci, 31(1):84, 23 Aug 2024
Cited by: 0 articles | PMID: 39180048 | PMCID: PMC11344461
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Jumonji histone demethylases are therapeutic targets in small cell lung cancer.
Nguyen A, Nuñez CG, Tran TA, Girard L, Peyton M, Catalan R, Guerena C, Avila K, Drapkin BJ, Chandra R, Minna JD, Martinez ED
Oncogene, 43(38):2885-2899, 18 Aug 2024
Cited by: 0 articles | PMID: 39154123 | PMCID: PMC11405284
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Antitumor Activity of a Novel LAIR1 Antagonist in Combination with Anti-PD1 to Treat Collagen-Rich Solid Tumors.
Rodriguez BL, Huang J, Gibson L, Fradette JJ, Chen HH, Koyano K, Cortez C, Li B, Ho C, Ashique AM, Lin VY, Crawley S, Roda JM, Chen P, Fan B, Kim J, Sissons J, Sitrin J, Kaplan DD, [...] Rivera LB
Mol Cancer Ther, 23(8):1144-1158, 01 Aug 2024
Cited by: 0 articles | PMID: 38648067
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Acknowledging and addressing real-world challenges to treating immune-related adverse events.
von Itzstein MS, Gerber DE, Bermas BL, Meara A
J Immunother Cancer, 12(7):e009540, 22 Jul 2024
Cited by: 0 articles | PMID: 39038920 | PMCID: PMC11268023
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KAP1 negatively regulates RNA polymerase II elongation kinetics to activate signal-induced transcription.
Hyder U, Challa A, Thornton M, Nandu T, Kraus WL, D'Orso I
Nat Commun, 15(1):5859, 12 Jul 2024
Cited by: 1 article | PMID: 38997286 | PMCID: PMC11245487
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Metabolic inflexibility promotes mitochondrial health during liver regeneration.
Wang X, Menezes CJ, Jia Y, Xiao Y, Venigalla SSK, Cai F, Hsieh MH, Gu W, Du L, Sudderth J, Kim D, Shelton SD, Llamas CB, Lin YH, Zhu M, Merchant S, Bezwada D, Kelekar S, Zacharias LG, [...] Mishra P
Science, 384(6701):eadj4301, 14 Jun 2024
Cited by: 2 articles | PMID: 38870309 | PMCID: PMC11232486
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Electron transport chain inhibition increases cellular dependence on purine transport and salvage.
Wu Z, Bezwada D, Cai F, Harris RC, Ko B, Sondhi V, Pan C, Vu HS, Nguyen PT, Faubert B, Cai L, Chen H, Martin-Sandoval M, Do D, Gu W, Zhang Y, Zhang Y, Brooks B, Kelekar S, [...] DeBerardinis RJ
Cell Metab, 36(7):1504-1520.e9, 13 Jun 2024
Cited by: 2 articles | PMID: 38876105 | PMCID: PMC11240302
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Capturing heterogeneity in PDX models: representation matters.
Sunil HS, O'Donnell KA
Nat Commun, 15(1):4652, 31 May 2024
Cited by: 1 article | PMID: 38821926 | PMCID: PMC11143235
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Immune checkpoint blockade resistance in lung cancer: emerging mechanisms and therapeutic opportunities.
Konen JM, Wu H, Gibbons DL
Trends Pharmacol Sci, 45(6):520-536, 13 May 2024
Cited by: 2 articles | PMID: 38744552
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Distinct autoantibody profiles across checkpoint inhibitor types and toxicities.
Mu-Mosley H, von Itzstein MS, Fattah F, Liu J, Zhu C, Xie Y, Wakeland EK, Park JY, Kahl BS, Diefenbach CS, Gerber DE
Oncoimmunology, 13(1):2351255, 09 May 2024
Cited by: 1 article | PMID: 38737792 | PMCID: PMC11085965
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CASi: A framework for cross-timepoint analysis of single-cell RNA sequencing data.
Wang Y, Flowers CR, Wang M, Huang X, Li Z
Sci Rep, 14(1):10633, 09 May 2024
Cited by: 0 articles | PMID: 38724550 | PMCID: PMC11082156
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A critical assessment of using ChatGPT for extracting structured data from clinical notes.
Huang J, Yang DM, Rong R, Nezafati K, Treager C, Chi Z, Wang S, Cheng X, Guo Y, Klesse LJ, Xiao G, Peterson ED, Zhan X, Xie Y
NPJ Digit Med, 7(1):106, 01 May 2024
Cited by: 8 articles | PMID: 38693429 | PMCID: PMC11063058
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Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC Paralogs.
Pal Choudhuri S, Girard L, Lim JYS, Wise JF, Freitas B, Yang D, Wong E, Hamilton S, Chien VD, Kim YJ, Gilbreath C, Zhong J, Phat S, Myers DT, Christensen CL, Mazloom-Farsibaf H, Stanzione M, Wong KK, Hung YP, [...] Drapkin BJ
Cancer Discov, 14(5):804-827, 01 May 2024
Cited by: 5 articles | PMID: 38386926 | PMCID: PMC11061613
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Molecular and Pathologic Characterization of YAP1-Expressing Small Cell Lung Cancer Cell Lines Leads to Reclassification as SMARCA4-Deficient Malignancies.
Ng J, Cai L, Cai L, Girard L, Prall OWJ, Rajan N, Khoo C, Batrouney A, Byrne DJ, Boyd DK, Kersbergen AJ, Christie M, Minna JD, Burr ML, Sutherland KD
Clin Cancer Res, 30(9):1846-1858, 01 May 2024
Cited by: 7 articles | PMID: 38180245 | PMCID: PMC11061608
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Highly variable timing renders immunotherapy efficacy and toxicity impractical biomarkers of one another in clinical practice.
von Itzstein MS, Yang Y, Wang Y, Hsiehchen D, Sheffield TY, Fattah F, Popat V, Ahmed M, Homsi J, Dowell JE, Rashdan S, Lohrey J, Hammers HJ, Hughes RS, Wang T, Xie Y, Gerber DE
Front Immunol, 15:1351739, 16 Apr 2024
Cited by: 0 articles | PMID: 38690281 | PMCID: PMC11058939
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SARS-CoV-2 Orf6 is positioned in the nuclear pore complex by Rae1 to inhibit nucleocytoplasmic transport.
Makio T, Zhang K, Love N, Mast FD, Liu X, Elaish M, Hobman T, Aitchison JD, Fontoura BMA, Wozniak RW
Mol Biol Cell, 35(5):ar62, 20 Mar 2024
Cited by: 0 articles | PMID: 38507240 | PMCID: PMC11151100
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An atlas of epithelial cell states and plasticity in lung adenocarcinoma.
Han G, Sinjab A, Rahal Z, Lynch AM, Treekitkarnmongkol W, Liu Y, Serrano AG, Feng J, Liang K, Khan K, Lu W, Hernandez SD, Liu Y, Cao X, Dai E, Pei G, Hu J, Abaya C, Gomez-Bolanos LI, [...] Kadara H
Nature, 627(8004):656-663, 28 Feb 2024
Cited by: 12 articles | PMID: 38418883 | PMCID: PMC10954546
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Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors.
Kim C, Wang XD, Liu Z, Hao J, Wang S, Li P, Zi Z, Ding Q, Jang S, Kim J, Luo Y, Huffman KE, Pal Choudhuri S, Del Rio S, Cai L, Liang H, Drapkin BJ, Minna JD, Yu Y
Sci Adv, 10(3):eadh2579, 19 Jan 2024
Cited by: 2 articles | PMID: 38241363 | PMCID: PMC10798557
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A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer.
Eglenen-Polat B, Kowash RR, Huang HC, Siteni S, Zhu M, Chen K, Bender ME, Mender I, Stastny V, Drapkin BJ, Raj P, Minna JD, Xu L, Shay JW, Akbay EA
Nat Commun, 15(1):672, 22 Jan 2024
Cited by: 0 articles | PMID: 38253555 | PMCID: PMC10803750
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Tumor- and circulating-free DNA methylation identifies clinically relevant small cell lung cancer subtypes.
Heeke S, Gay CM, Estecio MR, Tran H, Morris BB, Zhang B, Tang X, Raso MG, Rocha P, Lai S, Arriola E, Hofman P, Hofman V, Kopparapu P, Lovly CM, Concannon K, De Sousa LG, Lewis WE, Kondo K, [...] Heymach JV
Cancer Cell, 42(2):225-237.e5, 25 Jan 2024
Cited by: 14 articles | PMID: 38278149 | PMCID: PMC10982990
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Emerging Strategies in Lung Cancer Screening: Blood and Beyond.
Bhalla S, Yi S, Gerber DE
Clin Chem, 70(1):60-67, 01 Jan 2024
Cited by: 2 articles | PMID: 38175587
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Proteomics: A new dimension to decode small cell lung cancer.
Chen H, Drapkin BJ, Minna JD
Cell, 187(1):14-16, 01 Jan 2024
Cited by: 0 articles | PMID: 38181738
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Deep learning of cell spatial organizations identifies clinically relevant insights in tissue images.
Wang S, Rong R, Zhou Q, Yang DM, Zhang X, Zhan X, Bishop J, Chi Z, Wilhelm CJ, Zhang S, Pickering CR, Kris MG, Minna J, Xie Y, Xiao G
Nat Commun, 14(1):7872, 11 Dec 2023
Cited by: 3 articles | PMID: 38081823 | PMCID: PMC10713592
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