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Search life-sciences literature (45,104,206 articles, preprints and more)

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Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells.
Yamaguchi K, Chen X, Rodgers B, Miura F, Bashtrykov P, Bonhomme F, Salinas-Luypaert C, Haxholli D, Gutekunst N, Aygenli BÖ, Ferry L, Kirsh O, Laisné M, Scelfo A, Ugur E, Arimondo PB, Leonhardt H, Kanemaki MT, Bartke T, [...] Defossez PA
Nat Commun, 15(1):2960, 05 Apr 2024
Cited by: 1 article | PMID: 38580649 | PMCID: PMC10997609
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Specialized replication mechanisms maintain genome stability at human centromeres.
Scelfo A, Angrisani A, Grillo M, Barnes BM, Muyas F, Sauer CM, Leung CWB, Dumont M, Grison M, Mazaud D, Garnier M, Guintini L, Nelson L, Esashi F, Cortés-Ciriano I, Taylor SS, Déjardin J, Wilhelm T, Fachinetti D
Mol Cell, 84(6):1003-1020.e10, 14 Feb 2024
Cited by: 1 article | PMID: 38359824
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Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization.
Scelfo A, Barra V, Abdennur N, Spracklin G, Busato F, Salinas-Luypaert C, Bonaiti E, Velasco G, Bonhomme F, Chipont A, Tijhuis AE, Spierings DCJ, Guérin C, Arimondo P, Francastel C, Foijer F, Tost J, Mirny L, Fachinetti D
J Cell Biol, 223(4):e202307026, 20 Feb 2024
Cited by: 3 articles | PMID: 38376465 | PMCID: PMC10876481
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Centromere: A Trojan horse for genome stability.
Scelfo A, Fachinetti D
DNA Repair (Amst), 130:103569, 07 Sep 2023
Cited by: 3 articles | PMID: 37708591
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Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells
Defossez PA, Yamaguchi K, Chen X, Rodgers B, Miura F, Bashtrykov P, Ferry L, Kirsh O, Laisné M, Bonhomme F, Scelfo A, Salinas-Luypaert C, Ugur E, Arimondo P, Leonhardt H, Kanemaki M, Fachinetti D, Jeltsch A, Ito T
Research Square, 26 Jul 2023
Cited by: 0 articles | PPR: PPR698173
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Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells
Yamaguchi K, Chen X, Rodgers B, Miura F, Bashtrykov P, Ferry L, Kirsh O, Laisné M, Bonhomme F, Salinas-Luypaert C, Scelfo A, Ugur E, Arimondo PB, Leonhardt H, Kanemaki MT, Fachinetti D, Jeltsch A, Ito T, Defossez P
bioRxiv, 11 Jul 2023
Cited by: 0 articles | PPR: PPR690155
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Tunable DNMT1 degradation reveals cooperation of DNMT1 and DNMT3B in regulating DNA methylation dynamics and genome organization
Scelfo A, Barra V, Abdennur N, Spracklin G, Busato F, Salinas-Luypaert C, Bonaiti E, Velasco G, Chipont A, Guérin C, Tijhuis AE, Spierings DC, Francastel C, Foijer F, Tost J, Mirny L, Fachinetti D
bioRxiv, 09 May 2023
Cited by: 0 articles | PPR: PPR657050
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CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy.
Giunta S, Hervé S, White RR, Wilhelm T, Dumont M, Scelfo A, Gamba R, Wong CK, Rancati G, Smogorzewska A, Funabiki H, Fachinetti D
Proc Natl Acad Sci U S A, 118(10):e2015634118, 01 Mar 2021
Cited by: 34 articles | PMID: 33653953 | PMCID: PMC7958389
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CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy
Giunta S, Hervé S, White RR, Wilhelm T, Dumont M, Scelfo A, Gamba R, Wong CK, Rancati G, Smogorzewska A, Funabiki H, Fachinetti D
bioRxiv, 01 Sep 2020
Cited by: 0 articles | PPR: PPR208439
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Keeping the Centromere under Control: A Promising Role for DNA Methylation.
Scelfo A, Fachinetti D
Cells, 8(8):E912, 16 Aug 2019
Cited by: 24 articles | PMID: 31426433 | PMCID: PMC6721688
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Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities.
Scelfo A, Fernández-Pérez D, Tamburri S, Zanotti M, Lavarone E, Soldi M, Bonaldi T, Ferrari KJ, Pasini D
Mol Cell, 74(5):1037-1052.e7, 24 Apr 2019
Cited by: 86 articles | PMID: 31029542 | PMCID: PMC6561742
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Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type-dependent outcomes.
Pivetti S, Fernandez-Perez D, D'Ambrosio A, Barbieri CM, Manganaro D, Rossi A, Barnabei L, Zanotti M, Scelfo A, Chiacchiera F, Pasini D
Sci Adv, 5(5):eaav1594, 15 May 2019
Cited by: 17 articles | PMID: 31106267 | PMCID: PMC6520019
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Phosphorylation of CENP-A on serine 7 does not control centromere function.
Barra V, Logsdon GA, Scelfo A, Hoffmann S, Hervé S, Aslanian A, Nechemia-Arbely Y, Cleveland DW, Black BE, Fachinetti D
Nat Commun, 10(1):175, 11 Jan 2019
Cited by: 12 articles | PMID: 30635586 | PMCID: PMC6329807
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The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.
Streubel G, Watson A, Jammula SG, Scelfo A, Fitzpatrick DJ, Oliviero G, McCole R, Conway E, Glancy E, Negri GL, Dillon E, Wynne K, Pasini D, Krogan NJ, Bracken AP, Cagney G
Mol Cell, 70(2):371-379.e5, 29 Mar 2018
Cited by: 98 articles | PMID: 29606589
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Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.
Streubel G, Fitzpatrick DJ, Oliviero G, Scelfo A, Moran B, Das S, Munawar N, Watson A, Wynne K, Negri GL, Dillon ET, Jammula S, Hokamp K, O'Connor DP, Pasini D, Cagney G, Bracken AP
EMBO J, 36(15):2216-2232, 29 May 2017
Cited by: 32 articles | PMID: 28554894 | PMCID: PMC5538769
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Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice.
Rossi A, Ferrari KJ, Piunti A, Jammula S, Chiacchiera F, Mazzarella L, Scelfo A, Pelicci PG, Pasini D
Sci Adv, 2(10):e1600972, 07 Oct 2016
Cited by: 11 articles | PMID: 27730210 | PMCID: PMC5055382
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Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity.
Chiacchiera F, Rossi A, Jammula S, Piunti A, Scelfo A, Ordóñez-Morán P, Huelsken J, Koseki H, Pasini D
Cell Stem Cell, 18(1):91-103, 29 Oct 2015
Cited by: 64 articles | PMID: 26526724
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Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication.
Piunti A, Rossi A, Cerutti A, Albert M, Jammula S, Scelfo A, Cedrone L, Fragola G, Olsson L, Koseki H, Testa G, Casola S, Helin K, d'Adda di Fagagna F, d'Adda di Fagagna F, Pasini D
Nat Commun, 5:3649, 14 Apr 2014
Cited by: 63 articles | PMID: 24728135 | PMCID: PMC3996544
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The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?
Scelfo A, Piunti A, Pasini D
FEBS J, 282(9):1703-1722, 11 Nov 2014
Cited by: 36 articles | PMID: 25315766
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A novel self-lipid antigen targets human T cells against CD1c(+) leukemias.
Lepore M, de Lalla C, Gundimeda SR, Gsellinger H, Consonni M, Garavaglia C, Sansano S, Piccolo F, Scelfo A, Häussinger D, Montagna D, Locatelli F, Bonini C, Bondanza A, Forcina A, Li Z, Ni G, Ciceri F, Jenö P, [...] De Libero G
J Exp Med, 211(7):1363-1377, 16 Jun 2014
Cited by: 64 articles | PMID: 24935257 | PMCID: PMC4076585
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Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity.
Ferrari KJ, Scelfo A, Jammula S, Cuomo A, Barozzi I, Stützer A, Fischle W, Bonaldi T, Pasini D
Mol Cell, 53(1):49-62, 27 Nov 2013
Cited by: 276 articles | PMID: 24289921
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Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.
Vella P, Scelfo A, Jammula S, Chiacchiera F, Williams K, Cuomo A, Roberto A, Christensen J, Bonaldi T, Helin K, Pasini D
Mol Cell, 49(4):645-656, 24 Jan 2013
Cited by: 228 articles | PMID: 23352454
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High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells.
de Lalla C, Lepore M, Piccolo FM, Rinaldi A, Scelfo A, Garavaglia C, Mori L, De Libero G, Dellabona P, Casorati G, Casorati G
Eur J Immunol, 41(3):602-610, 18 Jan 2011
Cited by: 97 articles | PMID: 21246542
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