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Search life-sciences literature (45,105,671 articles, preprints and more)

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Real-life effectiveness on overall survival of continued immune checkpoint inhibition following progression in advanced melanoma: estimation from the Melbase cohort.
Macaire C, Lefevre W, Dalac S, Montaudié H, Legoupil D, Dereure O, Dutriaux C, Leccia MT, Aubin F, Grob JJ, Saiag P, De Quatrebarbes J, Maubec E, Lesimple T, Granel-Brocard F, Mortier L, Dalle S, Lebbé C, Prod'homme C
Melanoma Res, 11 Nov 2024
Cited by: 0 articles | PMID: 39527777
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Final Results for Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma.
Long GV, Hauschild A, Santinami M, Kirkwood JM, Atkinson V, Mandala M, Merelli B, Sileni VC, Nyakas M, Haydon A, Dutriaux C, Robert C, Mortier L, Schachter J, Schadendorf D, Lesimple T, Plummer R, Larkin J, Tan M, [...] Dummer R
N Engl J Med, 391(18):1709-1720, 19 Jun 2024
Cited by: 1 article | PMID: 38899716
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The combination of ipilimumab and nivolumab is still not reimbursed for BRAF-mutated melanoma patients in France: An unacceptable medical situation that raises ethical concerns.
Amini-Adle M, Arnault JP, Aubin F, Beneton N, Bens G, Brunet-Possenti F, Célerier P, Charles J, Crumbach L, Dalac S, Darras S, De Quatrebarbes J, Dinulescu M, Dutriaux C, Gaudy C, Gérard E, Giacchero D, Granel-Brocard F, Grange F, [...] the Ethical Group of the Société Française de Dermatologie French Dermatology Group
Ann Dermatol Venereol, 151(1):103243, 06 Feb 2024
Cited by: 0 articles | PMID: 38325268
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Safety and tolerability of long-term treatment with darolutamide in patients with metastatic castration-resistant prostate cancer.
Jones RH, Fizazi K, James ND, Tammela TL, Matsubara N, Priou F, Beuzeboc P, Lesimple T, Bono P, Kataja V, Garcia JA, Protheroe A, Shore N, Aspegren J, Joensuu H, Kuss I, Fiala-Buskies S, Vjaters E
Prostate Cancer Prostatic Dis, 27(4):786-789, 26 Oct 2023
Cited by: 1 article | PMID: 37884613 | PMCID: PMC11543588
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Inequality factors in access to early-phase clinical trials in oncology in France: results of the EGALICAN-2 study.
Charton E, Baldini C, Fayet Y, Schultz E, Auroy L, Vallier E, Italiano A, Robert M, Coquan E, Isambert N, Moreau P, Touzeau C, Le Tourneau C, Ghrieb Z, Kiladjian JJ, Delord JP, Gomez Roca C, Vey N, Barlesi F, [...] Besle S
ESMO Open, 8(4):101610, 01 Aug 2023
Cited by: 4 articles | PMID: 37536254 | PMCID: PMC10415590
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First-Line, Fixed-Duration Nivolumab Plus Ipilimumab Followed by Nivolumab in Clinically Diverse Patient Populations With Unresectable Stage III or IV Melanoma: CheckMate 401.
Dummer R, Corrie P, Gutzmer R, Meniawy TM, Del Vecchio M, Lebbé C, Guida M, Dutriaux C, Dreno B, Meyer N, Ferrucci PF, Dalle S, Khattak MA, Grob JJ, Briscoe K, Larkin J, Mansard S, Lesimple T, Guidoboni M, [...] Maio M
J Clin Oncol, 41(23):3917-3929, 12 Jun 2023
Cited by: 3 articles | PMID: 37307514
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Phase I Study of Androgen Deprivation Therapy in Combination with Anti-PD-1 in Melanoma Patients Pretreated with Anti-PD-1.
Robert C, Lebbé C, Lesimple T, Lundström E, Nicolas V, Gavillet B, Crompton P, Baroudjian B, Routier E, Lejeune FJ
Clin Cancer Res, 29(5):858-865, 01 Mar 2023
Cited by: 4 articles | PMID: 36516188
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The concomitant use of proton pump inhibitors and BRAF/MEK inhibitors in metastatic melanoma.
Poizeau F, Balusson F, Lemaitre F, Tron C, Pracht M, Russo D, Dinulescu M, Lesimple T, Oger E, Dupuy A
Br J Dermatol, 188(4):482-490, 01 Mar 2023
Cited by: 0 articles | PMID: 36760148
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Cost-Effectiveness Analysis of Sequential Treatment Strategies for Advanced Melanoma in Real Life in France.
Kandel M, Bardet A, Dalle S, Allayous C, Mortier L, Guillot B, Dutriaux C, Leccia MT, Dalac S, Montaudie H, Saiag P, Legoupil D, Brunet-Possenti F, Arnault JP, Quatrebarbes J, Beylot-Barry M, Maubec E, Lesimple T, Aubin F, [...] Borget I
Curr Oncol, 29(12):9255-9270, 27 Nov 2022
Cited by: 0 articles | PMID: 36547139 | PMCID: PMC9777106
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Non-V600E/K BRAF Mutations in Metastatic Melanoma: Molecular Description, Frequency, and Effectiveness of Targeted Therapy in a Large National Cohort.
Girod M, Dalle S, Mortier L, Dalac S, Leccia MT, Dutriaux C, Montaudié H, de Quatrebarbes J, Lesimple T, Brunet-Possenti F, Saiag P, Maubec E, Legoupil D, Stoebner PE, Arnault JP, Lefevre W, Lebbe C, Dereure O
JCO Precis Oncol, 6:e2200075, 01 Nov 2022
Cited by: 3 articles | PMID: 36356284
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Immune checkpoint inhibitors in patients aged 80 or older with advanced non-small cell lung cancer or melanoma: a real-life multicentre study.
Benguerfi S, Lesimple T, Houot R, Ricordel C, Legoupil D, Alleaume C, Lamy R, Deniel Lagadec D, Corre R
Acta Oncol, 61(11):1339-1346, 14 Oct 2022
Cited by: 1 article | PMID: 36239950
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Risk of irAEs in patients with autoimmune diseases treated by immune checkpoint inhibitors for stage III or IV melanoma: results from a matched case-control study.
Plaçais L, Dalle S, Dereure O, Trabelsi S, Dalac S, Legoupil D, Montaudié H, Arnault JP, De Quatrebarbes J, Saiag P, Brunet-Possenti F, Lesimple T, Maubec E, Aubin F, Granel-Brocard F, Grob JJ, Stoebner PE, Allayous C, Oriano B, [...] Lebbe C
Ann Rheum Dis, 81(10):1445-1452, 04 Jul 2022
Cited by: 15 articles | PMID: 35788496
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An open label, non-randomised, phase IIIb study of trametinib in combination with dabrafenib in patients with unresectable (stage III) or distant metastatic (stage IV) BRAF V600-mutant melanoma: A subgroup analysis of patients with brain metastases.
Dutriaux C, Robert C, Grob JJ, Mortier L, Dereure O, Lebbe C, Mansard S, Grange F, Neidhardt EM, Lesimple T, Machet L, Bedane C, Maillard H, Dalac-Rat S, Nardin C, Szenik A, Denden A, Saiag P
Eur J Cancer, 175:254-262, 25 Sep 2022
Cited by: 5 articles | PMID: 36170791
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Impact of Distribution of a Tip Sheet to Increase Early Detection and Prevention Behavior among First-Degree Relatives of Melanoma Patients: A Randomized Cluster Trial.
Marcé D, Le Vilain-Abraham F, Bridou M, Quéreux G, Dupuy A, Lesimple T, Le Corre Y, Wierzbicka-Hainaut E, Legoupil D, Célérier P, Maillard H, Machet L, Caille A
Cancers (Basel), 14(16):3864, 10 Aug 2022
Cited by: 0 articles | PMID: 36010858 | PMCID: PMC9406196
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MBD4 deficiency is predictive of response to immune checkpoint inhibitors in metastatic uveal melanoma patients.
Saint-Ghislain M, Derrien AC, Geoffrois L, Gastaud L, Lesimple T, Negrier S, Penel N, Kurtz JE, Le Corre Y, Dutriaux C, Gardrat S, Barnhill R, Matet A, Cassoux N, Houy A, Ramtohul T, Servois V, Mariani P, Piperno-Neumann S, [...] Rodrigues M
Eur J Cancer, 173:105-112, 19 Jul 2022
Cited by: 9 articles | PMID: 35863105
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Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma.
Bhave P, Ahmed T, Lo SN, Shoushtari A, Zaremba A, Versluis JM, Mangana J, Weichenthal M, Si L, Lesimple T, Robert C, Trojanello C, Wicky A, Heywood R, Tran L, Batty K, Dimitriou F, Stansfeld A, Allayous C, [...] Carlino MS
J Immunother Cancer, 10(7):e004668, 01 Jul 2022
Cited by: 15 articles | PMID: 35793872 | PMCID: PMC9260790
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Access to early-phase clinical trials in older patients with cancer in France: the EGALICAN-2 study.
Baldini C, Charton E, Schultz E, Auroy L, Italiano A, Robert M, Coquan E, Isambert N, Moreau P, Le Gouill S, Le Tourneau C, Ghrieb Z, Kiladjian JJ, Delord JP, Roca CG, Vey N, Barlesi F, Lesimple T, Penel N, [...] Besle S
ESMO Open, 7(3):100468, 06 May 2022
Cited by: 5 articles | PMID: 35533427 | PMCID: PMC9271476
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The Association Between Antibiotic Use and Outcome Among Metastatic Melanoma Patients Receiving Immunotherapy.
Poizeau F, Kerbrat S, Balusson F, Tattevin P, Revest M, Cattoir V, Luque-Paz D, Lesimple T, Pracht M, Dinulescu M, Russo D, Oger E, Dupuy A
J Natl Cancer Inst, 114(5):686-694, 01 May 2022
Cited by: 4 articles | PMID: 35253890 | PMCID: PMC9086805
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Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma.
Tawbi HA, Schadendorf D, Lipson EJ, Ascierto PA, Matamala L, Castillo Gutiérrez E, Rutkowski P, Gogas HJ, Lao CD, De Menezes JJ, Dalle S, Arance A, Grob JJ, Srivastava S, Abaskharoun M, Hamilton M, Keidel S, Simonsen KL, Sobiesk AM, [...] RELATIVITY-047 Investigators
N Engl J Med, 386(1):24-34, 01 Jan 2022
Cited by: 654 articles | PMID: 34986285 | PMCID: PMC9844513
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Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomised, controlled, phase 3 trial.
Eggermont AMM, Blank CU, Mandalà M, Long GV, Atkinson VG, Dalle S, Haydon AM, Meshcheryakov A, Khattak A, Carlino MS, Sandhu S, Larkin J, Puig S, Ascierto PA, Rutkowski P, Schadendorf D, Koornstra R, Hernandez-Aya L, Di Giacomo AM, [...] EORTC Melanoma Group
Lancet Oncol, 22(5):643-654, 12 Apr 2021
Cited by: 140 articles | PMID: 33857412
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Tolerance and Effectiveness of Targeted Therapies in Aged Patients with Metastatic Melanoma.
Becquart O, Oriano B, Dalle S, Mortier L, Leccia MT, Dutriaux C, Dalac S, Montaudié H, De Quatrebarbes J, Brunet-Possenti F, Saiag P, Lesimple T, Beylot-Barry M, Aubin F, Stoebner PE, Arnault JP, Dreno B, Porcher R, Lebbe C, Guillot B
Cancers (Basel), 13(12):3042, 18 Jun 2021
Cited by: 3 articles | PMID: 34207200 | PMCID: PMC8235702
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Prognostic impact of thyroid dysfunctions on progression-free survival in patients with metastatic melanoma treated with anti-PD-1 antibodies.
Frelau A, Jali E, Campillo-Gimenez B, Pracht M, Porneuf M, Dinulescu M, Edeline J, Boussemart L, Lesimple T
Melanoma Res, 31(3):208-217, 01 Jun 2021
Cited by: 7 articles | PMID: 33904517
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Efficacy, safety and factors associated with disease progression in patients with unresectable (stage III) or distant metastatic (stage IV) BRAF V600-mutant melanoma: An open label, non-randomized, phase IIIb study of trametinib in combination with dabrafenib.
Saiag P, Robert C, Grob JJ, Mortier L, Dereure O, Lebbe C, Mansard S, Grange F, Neidhardt EM, Lesimple T, Machet L, Bedane C, Maillard H, Dalac-Rat S, Nardin C, Szenik A, Denden A, Dutriaux C
Eur J Cancer, 154:57-65, 06 Jul 2021
Cited by: 6 articles | PMID: 34243078
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Tolerance and Effectiveness of Targeted Therapies in Aged Patients with Metastatic Melanoma
Becquart O, Oriano B, Dalle S, Mortier L, Leccia MT, Dutriaux C, Dalac S, Montaudié H, de Quatrebarbes J, Brunet-Possenti F, Saiag P, Lesimple T, Beylot-Barry M, Aubin F, Stoebner PE, Arnault JP, Dreno B, Porcher R, Lebbé C, Guillot B
Preprints.org, 17 Jun 2021
Cited by: 0 articles | PPR: PPR358174
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Adjuvant and concurrent temozolomide for 1p/19q non-co-deleted anaplastic glioma (CATNON; EORTC study 26053-22054): second interim analysis of a randomised, open-label, phase 3 study.
van den Bent MJ, Tesileanu CMS, Wick W, Sanson M, Brandes AA, Clement PM, Erridge S, Vogelbaum MA, Nowak AK, Baurain JF, Mason WP, Wheeler H, Chinot OL, Gill S, Griffin M, Rogers L, Taal W, Rudà R, Weller M, [...] Baumert BG
Lancet Oncol, 22(6):813-823, 14 May 2021
Cited by: 122 articles | PMID: 34000245 | PMCID: PMC8191233
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