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Search life-sciences literature (45,103,589 articles, preprints and more)

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Hypothesis: the generation of T cells directed against neoepitopes employing immune-mediating agents other than neoepitope vaccines.
Schlom J, Donahue RN, Palena C, Gameiro SR, Hodge JW, Hamilton DH, Gulley JL
J Immunother Cancer, 12(7):e009595, 08 Jul 2024
Cited by: 0 articles | PMID: 38977329 | PMCID: PMC11256020
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Fulvestrant increases the susceptibility of enzalutamide-resistant prostate cancer cells to NK-mediated lysis.
Dahut M, Fousek K, Horn LA, Angstadt S, Qin H, Hamilton DH, Schlom J, Palena C
J Immunother Cancer, 11(9):e007386, 01 Sep 2023
Cited by: 1 article | PMID: 37678915 | PMCID: PMC10496692
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Blockade of tumor-derived colony-stimulating factor 1 (CSF1) promotes an immune-permissive tumor microenvironment.
Maldonado MDM, Schlom J, Hamilton DH
Cancer Immunol Immunother, 72(10):3349-3362, 28 Jul 2023
Cited by: 7 articles | PMID: 37505292 | PMCID: PMC10491706
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Exploiting docetaxel-induced tumor cell necrosis with tumor targeted delivery of IL-12.
Franks SE, Santiago-Sanchez GS, Fabian KP, Solocinski K, Chariou PL, Hamilton DH, Kowalczyk JT, Padget MR, Gameiro SR, Schlom J, Hodge JW
Cancer Immunol Immunother, 72(8):2783-2797, 11 May 2023
Cited by: 3 articles | PMID: 37166485 | PMCID: PMC10361896
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An Interleukin-15 Superagonist Enables Antitumor Efficacy of Natural Killer Cells Against All Molecular Variants of SCLC.
Fousek K, Horn LA, Qin H, Dahut M, Iida M, Yacubovich D, Hamilton DH, Thomas A, Schlom J, Palena C
J Thorac Oncol, 18(3):350-368, 21 Nov 2022
Cited by: 8 articles | PMID: 36410696 | PMCID: PMC9974560
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Identification and validation of expressed HLA-binding breast cancer neoepitopes for potential use in individualized cancer therapy.
Reimann H, Nguyen A, Sanborn JZ, Vaske CJ, Benz SC, Niazi K, Rabizadeh S, Spilman P, Mackensen A, Ruebner M, Hein A, Beckmann MW, van der Meijden ED, Bausenwein J, Kretschmann S, Griffioen M, Schlom J, Gulley JL, Lee KL, [...] Kremer AN
J Immunother Cancer, 9(6):e002605, 01 Jun 2021
Cited by: 6 articles | PMID: 34172517 | PMCID: PMC8237736
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Vaccine Increases the Diversity and Activation of Intratumoral T Cells in the Context of Combination Immunotherapy.
Horn LA, Fousek K, Hamilton DH, Hodge JW, Zebala JA, Maeda DY, Schlom J, Palena C
Cancers (Basel), 13(5):968, 25 Feb 2021
Cited by: 7 articles | PMID: 33669155 | PMCID: PMC7956439
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Estimating Cumulative COVID-19 Infections by a Novel “Pandemic Rate Equation”
Hamilton DH
medRxiv, 21 Aug 2020
Cited by: 0 articles | PPR: PPR203802
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Combination therapies utilizing neoepitope-targeted vaccines.
Lee KL, Schlom J, Hamilton DH
Cancer Immunol Immunother, 70(4):875-885, 08 Oct 2020
Cited by: 11 articles | PMID: 33033852 | PMCID: PMC7979579
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Simultaneous inhibition of CXCR1/2, TGF-β, and PD-L1 remodels the tumor and its microenvironment to drive antitumor immunity.
Horn LA, Riskin J, Hempel HA, Fousek K, Lind H, Hamilton DH, McCampbell KK, Maeda DY, Zebala JA, Su Z, Schlom J, Palena C
J Immunother Cancer, 8(1):e000326, 01 Mar 2020
Cited by: 46 articles | PMID: 32188703 | PMCID: PMC7078948
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Cooperative Immune-Mediated Mechanisms of the HDAC Inhibitor Entinostat, an IL15 Superagonist, and a Cancer Vaccine Effectively Synergize as a Novel Cancer Therapy.
Hicks KC, Knudson KM, Lee KL, Hamilton DH, Hodge JW, Figg WD, Ordentlich P, Jones FR, Rabizadeh S, Soon-Shiong P, Schlom J, Gameiro SR
Clin Cancer Res, 26(3):704-716, 23 Oct 2019
Cited by: 24 articles | PMID: 31645354 | PMCID: PMC8274944
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The Evolution of Cement Fixation in Total Knee Arthroplasty.
Carpenter W, Hamilton DH, Luthringer T, Buchalter D, Schwarzkopf R
Surg Technol Int, 35:355-362, 01 Nov 2019
Cited by: 2 articles | PMID: 31524280
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Efficient Tumor Clearance and Diversified Immunity through Neoepitope Vaccines and Combinatorial Immunotherapy.
Lee KL, Benz SC, Hicks KC, Nguyen A, Gameiro SR, Palena C, Sanborn JZ, Su Z, Ordentlich P, Rohlin L, Lee JH, Rabizadeh S, Soon-Shiong P, Niazi K, Schlom J, Hamilton DH
Cancer Immunol Res, 7(8):1359-1370, 10 Jul 2019
Cited by: 18 articles | PMID: 31292145 | PMCID: PMC8202970
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Greater Rates of Acute Kidney Injury in African American Total Knee Arthroplasty Patients.
Womble TN, King JD, Hamilton DH, Shrout MA, Jacobs CA, Duncan ST
J Arthroplasty, 34(6):1240-1243, 31 Jan 2019
Cited by: 4 articles | PMID: 30824293 | PMCID: PMC6536310
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The Hidden Cost of Commercial Antibiotic-Loaded Bone Cement: A Systematic Review of Clinical Results and Cost Implications Following Total Knee Arthroplasty.
King JD, Hamilton DH, Jacobs CA, Duncan ST
J Arthroplasty, 33(12):3789-3792, 13 Aug 2018
Cited by: 17 articles | PMID: 30217400
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Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer.
Shah SR, David JM, Tippens ND, Mohyeldin A, Martinez-Gutierrez JC, Ganaha S, Schiapparelli P, Hamilton DH, Palena C, Levchenko A, Quiñones-Hinojosa A
Cell Rep, 21(2):495-507, 01 Oct 2017
Cited by: 32 articles | PMID: 29020634 | PMCID: PMC5637538
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Loss of the Cyclin-Dependent Kinase Inhibitor 1 in the Context of Brachyury-Mediated Phenotypic Plasticity Drives Tumor Resistance to Immune Attack.
Hamilton DH, McCampbell KK, Palena C
Front Oncol, 8:143, 03 May 2018
Cited by: 4 articles | PMID: 29774202 | PMCID: PMC5943507
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Phase I Study of a Poxviral TRICOM-Based Vaccine Directed Against the Transcription Factor Brachyury.
Heery CR, Palena C, McMahon S, Donahue RN, Lepone LM, Grenga I, Dirmeier U, Cordes L, Marté J, Dahut W, Singh H, Madan RA, Fernando RI, Hamilton DH, Schlom J, Gulley JL
Clin Cancer Res, 23(22):6833-6845, 30 Aug 2017
Cited by: 38 articles | PMID: 28855356 | PMCID: PMC5690815
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Development of Cancer Vaccines Targeting Brachyury, a Transcription Factor Associated with Tumor Epithelial-Mesenchymal Transition.
Hamilton DH, David JM, Dominguez C, Palena C
Cells Tissues Organs, 203(2):128-138, 20 Feb 2017
Cited by: 9 articles | PMID: 28214895 | PMCID: PMC5381518
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Brachyury, a vaccine target, is overexpressed in triple-negative breast cancer.
Hamilton DH, Roselli M, Ferroni P, Costarelli L, Cavaliere F, Taffuri M, Palena C, Guadagni F
Endocr Relat Cancer, 23(10):783-796, 01 Oct 2016
Cited by: 19 articles | PMID: 27580659 | PMCID: PMC5010091
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MUC1 upregulation promotes immune resistance in tumor cells undergoing brachyury-mediated epithelial-mesenchymal transition.
David JM, Hamilton DH, Palena C
Oncoimmunology, 5(4):e1117738, 06 Jan 2016
Cited by: 42 articles | PMID: 27141403 | PMCID: PMC4839328
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IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib.
Fernando RI, Hamilton DH, Dominguez C, David JM, McCampbell KK, Palena C
Oncotarget, 7(27):42031-42044, 01 Jul 2016
Cited by: 33 articles | PMID: 27248176 | PMCID: PMC5173114
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The IL-8/IL-8R Axis: A Double Agent in Tumor Immune Resistance.
David JM, Dominguez C, Hamilton DH, Palena C
Vaccines (Basel), 4(3):E22, 24 Jun 2016
Cited by: 205 articles | PMID: 27348007 | PMCID: PMC5041016
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Targeting Estrogen Receptor Signaling with Fulvestrant Enhances Immune and Chemotherapy-Mediated Cytotoxicity of Human Lung Cancer.
Hamilton DH, Griner LM, Keller JM, Hu X, Southall N, Marugan J, David JM, Ferrer M, Palena C
Clin Cancer Res, 22(24):6204-6216, 07 Jun 2016
Cited by: 32 articles | PMID: 27267852 | PMCID: PMC5143224
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AN ACCURATE GENETIC CLOCK
Hamilton DH
bioRxiv, 18 May 2015
Cited by: 0 articles | PPR: PPR35312
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