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Search life-sciences literature (45,103,589 articles, preprints and more)

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TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers
Kundu M, Greer YE, Lobanov A, Ridnour L, Donahue RN, Ng Y, Ratnayake S, Voeller D, Weltz S, Chen Q, Lockett SJ, Cam M, Meerzaman D, Wink DA, Weigert R, Lipkowitz S
bioRxiv, 23 Jul 2024
Cited by: 0 articles | PPR: PPR885363
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Peripheral immune biomarkers for immune checkpoint inhibition of solid tumours.
Goswami M, Toney NJ, Pitts SC, Celades C, Schlom J, Donahue RN
Clin Transl Med, 14(8):e1814, 01 Aug 2024
Cited by: 1 article | PMID: 39162097 | PMCID: PMC11333946
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Hypothesis: the generation of T cells directed against neoepitopes employing immune-mediating agents other than neoepitope vaccines.
Schlom J, Donahue RN, Palena C, Gameiro SR, Hodge JW, Hamilton DH, Gulley JL
J Immunother Cancer, 12(7):e009595, 08 Jul 2024
Cited by: 0 articles | PMID: 38977329 | PMCID: PMC11256020
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Soluble immune checkpoints: implications for cancer prognosis and response to immune checkpoint therapy and conventional therapies.
Pitts SC, Schlom J, Donahue RN
J Exp Clin Cancer Res, 43(1):155, 31 May 2024
Cited by: 2 articles | PMID: 38822401 | PMCID: PMC11141022
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Author Correction: Adjuvant nivolumab, capecitabine or the combination in patients with residual triple-negative breast cancer: the OXEL randomized phase II study.
Lynce F, Mainor C, Donahue RN, Geng X, Jones G, Schlam I, Wang H, Toney NJ, Jochems C, Schlom J, Zeck J, Gallagher C, Nanda R, Graham D, Stringer-Reasor EM, Denduluri N, Collins J, Chitalia A, Tiwari S, [...] Isaacs C
Nat Commun, 15(1):3957, 10 May 2024
Cited by: 0 articles | PMID: 38730268 | PMCID: PMC11087457
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Adjuvant nivolumab, capecitabine or the combination in patients with residual triple-negative breast cancer: the OXEL randomized phase II study.
Lynce F, Mainor C, Donahue RN, Geng X, Jones G, Schlam I, Wang H, Toney NJ, Jochems C, Schlom J, Zeck J, Gallagher C, Nanda R, Graham D, Stringer-Reasor EM, Denduluri N, Collins J, Chitalia A, Tiwari S, [...] Isaacs C
Nat Commun, 15(1):2691, 27 Mar 2024
Cited by: 2 articles | PMID: 38538574 | PMCID: PMC10973408
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Blood-based biomarkers in patients with non-small cell lung cancer treated with immune checkpoint blockade.
Tsai YT, Schlom J, Donahue RN
J Exp Clin Cancer Res, 43(1):82, 16 Mar 2024
Cited by: 5 articles | PMID: 38493133 | PMCID: PMC10944611
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Efficacy, safety, and biomarker analyses of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with advanced non-small cell lung cancer.
Rajan A, Abdul Sater H, Rahma O, Agajanian R, Lassoued W, Marté JL, Tsai YT, Donahue RN, Lamping E, Bailey S, Weisman A, Walter-Rodriguez B, Ito R, Vugmeyster Y, Sato M, Machl A, Schlom J, Gulley JL
J Immunother Cancer, 12(3):e008480, 13 Mar 2024
Cited by: 2 articles | PMID: 38485188 | PMCID: PMC10941133
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A T cell receptor β chain-directed antibody fusion molecule activates and expands subsets of T cells to promote antitumor activity.
Hsu J, Donahue RN, Katragadda M, Lowry J, Huang W, Srinivasan K, Guntas G, Tang J, Servattalab R, Moisan J, Tsai YT, Stoop A, Palakurthi S, Chopra R, Liu K, Wherry EJ, Su Z, Gulley JL, Bayliffe A, Schlom J
Sci Transl Med, 15(724):eadi0258, 29 Nov 2023
Cited by: 1 article | PMID: 38019931 | PMCID: PMC11421222
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Adjuvant nivolumab, capecitabine or the combination in patients with residual triple-negative breast cancer: the OXEL randomized phase II study
Lynce F, Mainor C, Donahue RN, Geng X, Jones G, Schlam I, Wang H, Toney NJ, Jochems C, Schlom J, Zeck J, Gallagher C, Nanda R, Graham D, Stringer-Reasor EM, Denduluri N, Collins J, Chitalia A, Tiwari S, [...] Isaacs C
medRxiv, 04 Dec 2023
Cited by: 0 articles | PPR: PPR768877
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Phosphoflow cytometry to assess cytokine signaling pathways in peripheral immune cells: potential for inferring immune cell function and treatment response in patients with solid tumors.
Toney NJ, Schlom J, Donahue RN
J Exp Clin Cancer Res, 42(1):247, 23 Sep 2023
Cited by: 4 articles | PMID: 37741983 | PMCID: PMC10517546
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Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies.
Goswami M, Schlom J, Donahue RN
Oncotarget, 14:758-774, 10 Aug 2023
Cited by: 0 articles | PMID: 38958745 | PMCID: PMC11221564
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Flutamide With or Without PROSTVAC in Non-metastatic Castration Resistant (M0) Prostate Cancer.
Madan RA, Bilusic M, Stein MN, Donahue RN, Arlen PM, Karzai F, Plimack E, Wong YN, Geynisman DM, Zibelman M, Mayer T, Strauss J, Chen G, Rauckhorst M, McMahon S, Couvillon A, Steinberg S, Figg WD, Dahut WL, [...] Gulley JL
Oncologist, 28(7):642-e561, 01 Jul 2023
Cited by: 2 articles | PMID: 37134294 | PMCID: PMC10322134
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First-in-human phase Ib trial of M9241 (NHS-IL12) plus avelumab in patients with advanced solid tumors, including dose expansion in patients with advanced urothelial carcinoma.
Strauss J, Deville JL, Sznol M, Ravaud A, Maruzzo M, Pachynski RK, Gourdin TS, Maio M, Dirix L, Schlom J, Donahue RN, Tsai YT, Wang X, Vugmeyster Y, Beier F, Seebeck J, Schroeder A, Chennoufi S, Gulley JL
J Immunother Cancer, 11(5):e005813, 01 May 2023
Cited by: 8 articles | PMID: 37236636 | PMCID: PMC10230972
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A Phase I Single-Arm Study of Biweekly NHS-IL12 in Patients With Metastatic Solid Tumors.
Gatti-Mays ME, Tschernia NP, Strauss J, Madan RA, Karzai FH, Bilusic M, Redman J, Sater HA, Floudas CS, Toney NJ, Donahue RN, Jochems C, Marté JL, Francis D, McMahon S, Lamping E, Cordes L, Schlom J, Gulley JL
Oncologist, 28(4):364-e217, 01 Apr 2023
Cited by: 6 articles | PMID: 36640137 | PMCID: PMC10078919
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Immune correlates with response in patients with metastatic solid tumors treated with a tumor targeting immunocytokine NHS-IL12.
Toney NJ, Gatti-Mays ME, Tschernia NP, Strauss J, Gulley JL, Schlom J, Donahue RN
Int Immunopharmacol, 116:109736, 16 Feb 2023
Cited by: 3 articles | PMID: 37234190 | PMCID: PMC10208359
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A Phase 2, Double-blind, Randomized Controlled Trial of PROSTVAC in Prostate Cancer Patients on Active Surveillance.
Parsons JK, Pinto PA, Pavlovich CP, Uchio E, Nguyen MN, Kim HL, Gulley JL, Sater HA, Jamieson C, Hsu CH, Wojtowicz M, House M, Schlom J, Donahue RN, Dahut WL, Madan RA, Bailey S, Centuori S, Bauman JE, [...] Chow HS
Eur Urol Focus, 9(3):447-454, 12 Dec 2022
Cited by: 1 article | PMID: 36517408 | PMCID: PMC10258223
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Systemic immune changes accompany combination treatment with immunotoxin LMB-100 and nab-paclitaxel.
Pegna GJ, Lee MJ, Peer CJ, Ahmad MI, Venzon DJ, Yu Y, Yuno A, Steinberg SM, Cao L, Figg WD, Donahue RN, Hassan R, Pastan I, Trepel JB, Alewine C
Cancer Med, 12(4):4236-4249, 08 Oct 2022
Cited by: 3 articles | PMID: 36208017 | PMCID: PMC9972172
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Phase 1 trial of CV301 in combination with anti-PD-1 therapy in nonsquamous non-small cell lung cancer.
Rajan A, Gray JE, Devarakonda S, Birhiray R, Korchin B, Menius E, Donahue RN, Schlom J, Gulley JL
Int J Cancer, 152(3):447-457, 09 Sep 2022
Cited by: 3 articles | PMID: 36054490 | PMCID: PMC10690498
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Contrasting autoimmune and treatment effects reveals baseline set points of immune toxicity following checkpoint inhibitor treatment
Zhao C, Mulè MP, Martins AJ, Pinal-Fernandez I, Donahue RN, Chen J, Schlom J, Gulley JL, Mammen A, Tsang JS, Rajan A
bioRxiv, 06 Jun 2022
Cited by: 0 articles | PPR: PPR511159
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Immune correlates of clinical parameters in patients with HPV-associated malignancies treated with bintrafusp alfa.
Tsai YT, Strauss J, Toney NJ, Jochems C, Venzon DJ, Gulley JL, Schlom J, Donahue RN
J Immunother Cancer, 10(4):e004601, 01 Apr 2022
Cited by: 12 articles | PMID: 35418484 | PMCID: PMC9014099
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Joint-Predominant Rheumatic Complications of Immune Checkpoint Inhibitor Therapy in Patients with Thymic Epithelial Tumors.
Mullenix C, Ballman M, Chen H, Swift S, McAdams MJ, Tsai YT, Donahue RN, Poretta T, Gupta S, Loehrer PJ, Schlom J, Gulley JL, Rajan A
Oncologist, 27(4):e353-e356, 01 Apr 2022
Cited by: 1 article | PMID: 35380721 | PMCID: PMC8982432
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A Randomized Phase II Trial of mFOLFOX6 + Bevacizumab Alone or with AdCEA Vaccine + Avelumab Immunotherapy for Untreated Metastatic Colorectal Cancer.
Redman JM, Tsai YT, Weinberg BA, Donahue RN, Gandhy S, Gatti-Mays ME, Abdul Sater H, Bilusic M, Cordes LM, Steinberg SM, Marte JL, Jochems C, Kim SS, Marshall JL, McMahon S, Redmond E, Schlom J, Gulley JL, Strauss J
Oncologist, 27(3):198-209, 01 Mar 2022
Cited by: 17 articles | PMID: 35274710 | PMCID: PMC8914498
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A randomized phase 2 study of bicalutamide with or without metformin for biochemical recurrence in overweight or obese prostate cancer patients (BIMET-1).
Bilusic M, Toney NJ, Donahue RN, Wroblewski S, Zibelman M, Ghatalia P, Ross EA, Karzai F, Madan RA, Dahut WL, Gulley JL, Schlom J, Plimack ER, Geynisman DM
Prostate Cancer Prostatic Dis, 25(4):735-740, 25 Jan 2022
Cited by: 11 articles | PMID: 35079115 | PMCID: PMC9309187
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Phase 1 open-label trial of intravenous administration of MVA-BN-brachyury-TRICOM vaccine in patients with advanced cancer.
DeMaria PJ, Lee-Wisdom K, Donahue RN, Madan RA, Karzai F, Schwab A, Palena C, Jochems C, Floudas C, Strauss J, Marté JL, Redman JM, Dombi E, Widemann B, Korchin B, Adams T, Pico-Navarro C, Heery C, Schlom J, [...] Bilusic M
J Immunother Cancer, 9(9):e003238, 01 Sep 2021
Cited by: 16 articles | PMID: 34479925 | PMCID: PMC8420671
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