CERN Accelerating science

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1.
Interpretation of the horizontal beam response near the third integer resonance / Cortés García, E.C. (DESY ; Darmstadt, GSI) ; Niedermayer, P. (Darmstadt, GSI) ; Singh, R. (Darmstadt, GSI) ; Taylor, R. (CERN ; Imperial Coll., London) ; Feldmeier, E. (Heidelberg U.) ; Hun, M. (Heidelberg U.) ; Benedetto, E. (Unlisted, CH) ; Haberer, T. (Heidelberg U.)
The beam response to an external periodic excitation delivers relevant information about the optics, tune distribution and stability of a circulating beam in a storage ring. [...]
arXiv:2404.02576.
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Fulltext
2.
South East European International Institute for Sustainable Technologies (SEEIIST) / Amaldi, Ugo (TERA, Novara) ; Benedetto, Elena (TERA, Novara) ; Damjanovic, Sanja (Unlisted, CH) ; Dosanjh, Manjit (CERN) ; Durante, Marco (Darmstadt, GSI ; Darmstadt, Tech. U.) ; Georgieva, Petya (TERA, Novara) ; Haberer, Thomas (HITS, Heidelberg) ; Plesko, Mark (Cosylab, Ljubljana) ; Ristova, Mimoza (CERN ; Skopje U.) ; Rossi, Sandro (Unlisted, IT) et al.
The South East European International Institute for Sustainable Technologies (SEEIIST) was proposed in 2016 at the World Academy of Art and Science, with the objective of building a facility for charged particle cancer therapy for the South Eastern European countries. SEEIIST will offer the world-class research needed to reduce or even revert the brain drain that is causing a shortage of talent and economic losses in South East Europe. [...]
2021 - Published in : Front. Phys. 8 (2021) 567466
3.
Dosimetric validation of Monte Carlo and analytical dose engines with raster-scanning $^1$H, $^4$He, $^{12}$C, and $^{16}$O ion-beams using an anthropomorphic phantom / Mein, Stewart (NCRO, Heidelberg ; Heidelberg U. Hospital ; DKFZ, Heidelberg) ; Kopp, Benedikt (Heidelberg U. Hospital ; Heidelberg U. ; DKFZ, Heidelberg) ; Tessonnier, Thomas (Centre Francois Baclesse, Caen) ; Ackermann, Benjamin (Heidelberg U. Hospital) ; Ecker, Swantje (Heidelberg U. Hospital) ; Bauer, Julia (Heidelberg U. Hospital) ; Choi, Kyungdon (CNAO, Pavia) ; Aricò, Giulia (CERN) ; Ferrari, Alfredo (CERN) ; Haberer, Thomas (Heidelberg U. Hospital) et al.
With high-precision radiotherapy on the rise towards mainstream healthcare, comprehensive validation procedures are essential, especially as more sophisticated technologies emerge. In preparation for the upcoming translation of novel ions, case-/disease-specific ion-beam selection and advanced multi-particle treatment modalities at the Heidelberg Ion-beam Therapy Center (HIT), we quantify the accuracy limits in particle therapy treatment planning under complex heterogeneous conditions for the four ions ($^1$H, $^4$He, $^{12}$C, $^{16}$O) using a Monte Carlo Treatment Planning platform (MCTP), an independent GPU-accelerated analytical dose engine developed in-house (FRoG) and the clinical treatment planning system (Syngo RT Planning). [...]
2019 - 9 p. - Published in : Physica Medica 64 (2019) 123-131
4.
Towards a Common Reliability & Availability Information System for Particle Accelerator Facilities / Höppner, Klaus (HITS, Heidelberg) ; Gutleber, Johannes (CERN) ; Haberer, Thomas (HITS, Heidelberg) ; Humer, Heinrich (TU Vienna) ; Niemi, Arto (CERN) ; Pasic, Kemal (HITS, Heidelberg) ; Peters, Andreas (HITS, Heidelberg)
Failure event and maintenance record based data collection systems have a long tradition in industry. Today, the particle accelerator community does not possess a common platform that permits storing and sharing reliability and availability information in an efficient way. [...]
2020 - 4 p. - Published in : 10.18429/JACoW-ICALEPCS2019-MOPHA063 Fulltext: PDF;
In : 17th Biennial International Conference on Accelerator and Large Experimental Physics Control Systems (ICALEPCS), New York, United States, 5 - 11 Oct 2019, pp.356
5.
A novel facility for cancer therapy and biomedical research with heavy ions for the South East European International Institute for Sustainable Technologies / Damjanovic, Sanja (SEEIIST Association (CH)) ; Amaldi, Ugo (TERA Foundation (IT)) ; Benedetto, Elena (SEEIIST Association (CH)) ; Bisoffi, Giovanni (Universita e INFN, Legnaro (IT)) ; Dosanjh, Manjit ; Durante, Marco ; Foka, Yiota (GSI - Helmholtzzentrum fur Schwerionenforschung GmbH (DE)) ; Grubling, Peter (SEEIIST Association (CH)) ; Rossi, Sandro ; Sapinski, Mariusz (SEEIIST Association (CH)) et al.
The South East European International Institute for Sustainable Technologies (SEEIIST) proposes the construction of a major joint Research Infrastructure in the region, to rebuild cooperation after the recent wars and overcome lasting consequences like technology deficits and brain drain, having at its core a facility for cancer therapy and biomedical research with heavy ions. [...]
CERN-ACC-NOTE-2021-0019 ; NIMMS-Note-005.
- 2021. - 4 p.
Full text - Full text
6.
South East European International Institute for Sustainable Technologies (SEEIIST) / Amaldi, Ugo (TERA, Novara) ; Benedetto, Elena (TERA, Novara) ; Damjanovic, Sanja (SEEIIST Association) ; Dosanjh, Manjit (CERN ; U. Oxford (main)) ; Durante, Marco (Darmstadt, GSI ; Darmstadt, Tech. U.) ; Georgieva, Petya (TERA, Novara) ; Haberer, Thomas (HITS, Heidelberg) ; Plesko, Mark (Cosylab, Ljubljana) ; Ristova, Mimoza (SEEIIST Association ; Faculty of Natural Sciences, UKIM, Skopje, North Macedonia) ; Rossi, Sandro (CNAO) et al.
The South East European International Institute for Sustainable Technologies (SEEIIST) was proposed in 2016 at the World Academy of Art and Science, with the objective of building a facility for charged particle cancer therapy for the South Eastern European countries. [...]
15 p.
Full text
7.
Measurement of $^4$He charge- and mass-changing cross sections on H, C, O, and Si targets in the energy range 70–220 MeV/u for radiation transport calculations in ion-beam therapy / Horst, Felix (Giessen U. ; Darmstadt, GSI) ; Aricò, Giulia (CERN) ; Brinkmann, Kai-Thomas (U. Giessen, II. Phys. Inst.) ; Brons, Stephan (Heidelberg U.) ; Ferrari, Alfredo (CERN) ; Haberer, Thomas (Heidelberg U.) ; Mairani, Andrea (Heidelberg U. ; CNAO, Pavia) ; Parodi, Katia (Munich U.) ; Reidel, Claire-Anne (Darmstadt, GSI ; Strasbourg, IPHC) ; Weber, Uli (Darmstadt, GSI) et al.
Measured charge- and mass-changing cross sections for the systems He4+C12, He4+O16, He4+Si28, and He4+H1 in the energy range 70–220MeV/u are presented. The cross sections were obtained via the attenuation method where a ΔE-E scintillator telescope was used for particle identification. [...]
2019 - 11 p. - Published in : Phys. Rev. C 99 (2019) 014603 Fulltext from publisher: PDF;
8.
Optimizing the modified microdosimetric kinetic model input parameters for proton and $^4$He ion beam therapy application / Mairani, A (CNAO, Milan ; Heidelberg Ion Beam Therapy Center, Heidelberg) ; Magro, G (CNAO, Milan) ; Tessonnier, T (Heidelberg U. Hospital ; LMU Munich (main)) ; Böhlen, T T (EBG MedAustron GmbH, Wiener Neustadt) ; Molinelli, S (CNAO, Milan) ; Ferrari, A (CERN) ; Parodi, K (Heidelberg Ion Beam Therapy Center, Heidelberg ; Heidelberg U. Hospital ; LMU Munich (main)) ; Debus, J (Heidelberg Ion Beam Therapy Center, Heidelberg ; Heidelberg U. Hospital) ; Haberer, T (Heidelberg Ion Beam Therapy Center, Heidelberg)
Models able to predict relative biological effectiveness (RBE) values are necessary for an accurate determination of the biological effect with proton and $^4$He ion beams. This is particularly important when including RBE calculations in treatment planning studies comparing biologically optimized proton and $^4$He ion beam plans. [...]
2017 - 13 p. - Published in : Phys. Med. Biol. 62 (2017) N244-N256
9.
Dosimetric verification in water of a Monte Carlo treatment planning tool for proton, helium, carbon and oxygen ion beams at the Heidelberg Ion Beam Therapy Center / Tessonnier, T (Heidelberg U. Hospital ; LMU Munich (main)) ; Böhlen, TT ; Ceruti, F (CERN) ; Ferrari, A (CERN) ; Sala, P (CERN ; INFN, Milan) ; Brons, S (HITS, Heidelberg) ; Haberer, T (HITS, Heidelberg) ; Debus, J (Heidelberg U. Hospital ; HITS, Heidelberg) ; Parodi, K (Heidelberg U. Hospital ; LMU Munich (main)) ; Mairani, A (HITS, Heidelberg)
The introduction of 'new' ion species in particle therapy needs to be supported by a thorough assessment of their dosimetric properties and by treatment planning comparisons with clinically used proton and carbon ion beams. In addition to the latter two ions, helium and oxygen ion beams are foreseen at the Heidelberg Ion Beam Therapy Center (HIT) as potential assets for improving clinical outcomes in the near future. [...]
2017 - 16 p. - Published in : Phys. Med. Biol. 62 (2017) 6579-6594
10.
Helium ions at the heidelberg ion beam therapy center: comparisons between FLUKA Monte Carlo code predictions and dosimetric measurements / Tessonnier, T (Heidelberg U. Hospital ; LMU Munich (main)) ; Mairani, A (HITS, Heidelberg) ; Brons, S (HITS, Heidelberg) ; Sala, P (CERN ; INFN, Milan) ; Cerutti, F (CERN) ; Ferrari, A (CERN) ; Haberer, T (HITS, Heidelberg) ; Debus, J (Heidelberg U. Hospital ; HITS, Heidelberg) ; Parodi, K (Heidelberg U. Hospital ; LMU Munich (main))
In the field of particle therapy helium ion beams could offer an alternative for radiotherapy treatments, owing to their interesting physical and biological properties intermediate between protons and carbon ions. We present in this work the comparisons and validations of the Monte Carlo FLUKA code against in-depth dosimetric measurements acquired at the Heidelberg Ion Beam Therapy Center (HIT). [...]
2017 - 20 p. - Published in : Phys. Med. Biol. 62 (2017) 6784-6803

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