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The FOOT FragmentatiOn Of Target Experiment / Alexandrov, Andrey (INFN, Naples) ; Alpat, Behcet (INFN, Perugia) ; Ambrosi, Giovanni (INFN, Perugia) ; Argirò, Stefano (Turin U. ; INFN, Turin) ; Battistoni, Giuseppe (INFN, Milan) ; Bisogni, Maria Giuseppina (Pisa U. ; INFN, Pisa) ; Belcari, Nicola (Pisa U. ; INFN, Pisa) ; Biondi, Silvia (INFN, Bologna ; Bologna U.) ; Bruni, Graziano (INFN, Bologna) ; Camarlinghi, Niccolò (Pisa U. ; INFN, Pisa) et al.
In proton-therapy clinical practice a constant RBE equal to 1.1 is adopted, regardless of the demonstrated RBE variations, which depends on physical and biological parameters. Among other mechanisms, nuclear interactions might influence the proton-RBE due to secondary heavier particles produced by target fragmentation that can significantly contribute to the total dose: an un-wanted and undetermined increase of normal tissues complications probability may occur. [...]
Geneva : CERN, 2019 - 8 p. - Published in : CERN Proc.: 1 (2019) , pp. 305-312 Fulltext: PDF;
In : 15th International Conference on Nuclear Reaction Mechanisms, Varenna, Italy, 11 - 15 Jun 2018, pp.305-312

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