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A High-Resolution PET Demonstrator using a Silicon “Magnifying Glass”
/ Clinthorne, Neal ; Cochran, Eric ; Chesi, Enrico (CERN) ; Grkovski, Milan ; Grošičar, Borut ; Honscheid, Klaus ; Huh, Sam S ; Kagan, Harris ; Lacasta, Carlos ; Brzezinski, Karol et al.
To assist ongoing investigations of the limits of the tradeoff between spatial resolution and noise in PET imaging, several PET instruments based on silicon-pad detectors have been developed. The latest is a segment of a dual-ring device to demonstrate that excellent reconstructed image resolution can be achieved with a scanner that uses highresolution detectors placed close to the object of interest or surrounding a small field-of-view in combination with detectors having modest resolution at larger radius. [...]
2012 - 9 p.
- Published in : Phys. Procedia 37 (2012) 1488-1496
Elsevier Open Access article: PDF;
In : 2nd International Conference on Technology and Instrumentation in Particle Physics, Chicago, IL, USA, 9 - 14 Jun 2011, pp.1488-1496
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3.
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Performance of the AX-PET demonstrator
/ Beltrame, P (CERN) ; Bolle, E (Oslo U.) ; Braem, A (CERN) ; Casella, C (Zurich, ETH) ; Chesi, E (Ohio State U.) ; Clinthorne, N (Michigan U.) ; De Leo, R (INFN, Bari) ; Dissertori, G (Zurich, ETH) ; Djambazov, L (Zurich, ETH) ; Fanti, V (CERN) et al.
The goal of the AX-PET project is to build and test a demonstrator for a high resolution, high sensitivity PET scanner, based on a novel geometrical concept of long axially oriented crystals. The demonstrator comprises two PET modules used in coin cidence. [...]
2011 - 3 p.
- Published in : Nucl. Phys. B, Proc. Suppl. 215 (2011) 34-36
In : 12th Topical Seminar on Innovative Particle and Radiation Detectors, Sienna, Italy, 7-10 Jun 2010, pp.34-36
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4.
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Silicon as an unconventional detector in positron emission tomography
/ Clinthorne, Neal (Michigan U.) ; Brzezinski, Karol (Valencia U., IFIC) ; Chesi, Enrico (CERN) ; Cochran, Eric (Ohio State U.) ; Grkovski, Milan (Stefan Inst., Ljubljana) ; Grosicar, Borut (Stefan Inst., Ljubljana) ; Honscheid, Klaus (Ohio State U.) ; Huh, Sam (Michigan U.) ; Kagan, Harris (Ohio State U.) ; Lacasta, Carlos (Valencia U., IFIC) et al.
Positron emission tomography (PET) is a widely used technique in medical imaging and in studying small animal models of human disease. In the conventional approach, the 511keV annihilation photons emitted from a patient or small animal are detected by a ring of scintillators such as LYSO read out by arrays of photodetectors. [...]
2013 - 5 p.
- Published in : Nucl. Instrum. Methods Phys. Res., A 699 (2013) 216-220
In : The 8th international "Hiroshima" Symposium on the Development and Application of Semiconductor Tracking Detectors, Taipei, Taiwan, 5 - 8 Dec 2011, pp.216-220
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5.
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Demonstration of an Axial PET concept for brain and small animal imaging
/ Beltrame, P (CERN) ; Nappi, E (INFN, Bari) ; Clinthorne, N (Michigan U.) ; Meddi, F (Rome U.) ; Kagan, H (Ohio State U.) ; Braem, A (CERN) ; Pauss, F (Zurich, ETH) ; Djambazov, L (Zurich, ETH) ; Lustermann, W (Zurich, ETH) ; Weilhammer, P (Ohio State U.) et al.
Standard Positron Emission Tomography (PET) cameras need to reach a compromise between spatial resolution and sensitivity. To overcome this limitation we developed a novel concept of PET. [...]
2011
- Published in : Nucl. Instrum. Methods Phys. Res., A 628 (2011) 426-429
In : 12th Vienna Conference on Instrumentation, Vienna, Austria, 15 - 20 Feb 2010, pp.426-429
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6.
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Construction and tests of demonstrator modules for a 3-D axial PET system for brain or small animal imaging
/ Chesi, E (Ohio State U.) ; Nappi, E (INFN, Bari) ; Clinthorne, N (Michigan U.) ; Pauss, P (Zurich, ETH) ; Meddi, F (Rome U.) ; Beltrame, P (CERN) ; Kagan, H (Ohio State U.) ; Braem, A (CERN) ; Casella, C (Zurich, ETH) ; Djambazov, G (Zurich, ETH) et al.
The design and construction of a PET camera module with high sensitivity, full 3-D spatial reconstruction and very good energy resolution is presented. The basic principle consists of an axial arrangement of long scintillation crystals around the Field Of View (FOV), providing a measurement of the transverse coordinates of the interacting 511 keV gamma ray. [...]
2011
- Published in : Nucl. Instrum. Methods Phys. Res., A 636 (2011) S226-S230
In : 7th International Symposium on the Development and Application of Semiconductor Tracking Detectors, Hiroshima, Japan, 29 Aug - 01 Sep 2009, pp.S226-S230
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7.
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The AX-PET project : Demonstration of a high resolution axial 3D PET
/ Bolle, E (Oslo U.) ; Braem, A (CERN) ; Casella, C (Zurich, ETH) ; Chesi, E (Ohio State U.) ; Clinthorne, N (Michigan U.) ; Cochran, E (Ohio State U.) ; De Leo, R (INFN, Bari) ; Dissertori, G (Zurich, ETH) ; Djambazov, G (Zurich, ETH) ; Fanti, V (CERN) et al.
The AX-PET is a new geometrical concept for a high resolution 3D PET scanner, based on matrices of axially oriented LYSO crystals interleaved by stacks of WLS, both individually read out by G-APDs. A PET demonstrator, based on two detector modules used in coincidence, is currently under construction..
2010
- Published in : Nucl. Instrum. Methods Phys. Res., A 623 (2010) 214-216
In : 11th Pisa Meeting on Advanced Detectors on Frontier Detectors For Frontier Physics, La Biodola, Italy, 24 - 30 May 2009, pp.214-216
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8.
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A device to measure the effects of strong magnetic fields on the image resolution of PET scanners
/ Burdette, D (Ohio State U.) ; Albani, D (Ohio State U.) ; Chesi, E (CERN) ; Clinthorne, N H (Michigan U.) ; Cochran, E (Ohio State U.) ; Honscheid, K (Ohio State U.) ; Huh, S S (Michigan U.) ; Kagan, H (Ohio State U.) ; Knopp, M (Ohio State U.) ; Lacasta, C (Valencia U., IFIC) et al.
Very high resolution images can be achieved in small animal PET systems utilizing solid state silicon pad detectors. As these systems approach sub-millimeter resolutions, the range of the positron is becoming the dominant contribution to image blur. [...]
2009
- Published in : Nucl. Instrum. Methods Phys. Res., A 609 (2009) 263-271
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9.
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AX-PET : A novel PET detector concept with full 3D reconstruction
/ Braem, A (CERN) ; Joram, C (CERN) ; Séguinot, J (CERN) ; Dissertori, G (Zurich, ETH) ; Djambazov, L (Zurich, ETH) ; Lustermann, W (Zurich, ETH) ; Nessi-Tedaldi, F (Zurich, ETH) ; Pauss, F (Zurich, ETH) ; Schinzel, D (Zurich, ETH) ; Solevi, P (Zurich, ETH) et al.
We describe the concept and first experimental tests of a novel 3D axial Positron Emission Tomography (PET) geometry. It allows for a new way of measuring the interaction point in the detector with very high precision. [...]
2009
- Published in : Nucl. Instrum. Methods Phys. Res., A 610 (2009) 192-195
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10.
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Development of a High Precision Axial 3-D PET for Brain Imaging
/ Bolle, E (Oslo U.) ; Braem, A (CERN) ; Casella, C (Zurich, ETH) ; Chesi, E (Ohio State U.) ; Clinthorne, N (Michigan U.) ; Cochran, E (Ohio State U.) ; De Leo, R (INFN, Bari) ; Dissertori, G (Zurich, ETH) ; Djambazov, L (Zurich, ETH) ; Honscheid, K (Ohio State U.) et al.
We describe a PET device based on a novel method to extract the coordinates of the interaction point of the 511 keV γ rays from 100 mm long and thin LYSO (Lutetium Yttrium OxyorthoSilicate) scintillator bars, positioned axially in the tomograph. The coordinate along the hit crystal is measured by using a hodoscope of Wave Length Shifting (WLS) plastic strips mounted perpendicularly to each plane of scintillators. [...]
2009
- Published in : Nucl. Phys. B, Proc. Suppl. 197 (2009) 19-23
In : 11th Topical Seminar on Innovative Particle and Radiation Detectors, Sienna, Italy, 01 Oct - 04 Oct 2008, pp.19-23
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