CERN Accelerating science

CERN Document Server 3 εγγραφές βρέθηκαν  Η έρευνα πήρε 2.02 δευτερόλεπτα. 
1.
Preclinical investigation of [$^{149}$Tb]Tb-DOTATATE and [$^{149}$Tb]Tb-DOTA-LM3 for tumor-targeted alpha therapy / Mapanao, Ana Katrina (PSI, Villigen) ; Busslinger, Sarah D (PSI, Villigen) ; Mehta, Avni (PSI, Villigen) ; Kegler, Kristel (Unlisted, CH) ; Favaretto, Chiara (PSI, Villigen ; Unlisted, CH) ; Grundler, Pascal V (PSI, Villigen) ; Talip, Zeynep (PSI, Villigen) ; Köster, Ulli (Laue-Langevin Inst.) ; Johnston, Karl (CERN) ; Schibli, Roger (PSI, Villigen ; Zurich, ETH) et al.
Terbium-149 is a short-lived α-particle emitter, potentially useful for tumor-targeted therapy. The aim of this study was to investigate terbium-149 in combination with the somatostatin receptor (SSTR) agonist DOTATATE and the SSTR antagonist DOTA-LM3. [...]
2025 - 16 p. - Published in : European Journal of Nuclear Medicine and Molecular Imaging 52 (2025) 1383-1398
2.
Terbium-149 production: a focus on yield and quality improvement towards preclinical application / Favaretto, C (Basel U. ; PSI, Villigen) ; Grundler, P V (PSI, Villigen) ; Talip, Z (PSI, Villigen) ; Köster, U (Laue-Langevin Inst. ; CERN) ; Johnston, K (CERN) ; Busslinger, S D (PSI, Villigen) ; Sprung, P (PSI, Villigen) ; Hillhouse, C C (PSI, Villigen) ; Eichler, R (PSI, Villigen ; Bern U.) ; Schibli, R (PSI, Villigen ; Zurich, ETH) et al.
Terbium-149 (T$_{1/2}$ = 4.1 h, E$_{α}$ = 3.98 MeV (16.7%), 28 µm range in tissue) is a radionuclide with potential for targeted alpha therapy. Due to the negligible emission of α-emitting daughter nuclides, toxicity to healthy tissue may be reduced in comparison with other α-particle emitters. [...]
2024 - 12 p. - Published in : Sci. Rep. 14 (2024) 3284 Fulltext: PDF;
3.
Terbium-149 for targeted alpha therapy / Borgna, Francesca (PSI) ; Favaretto, Chiara (PSI) ; Grundler, Pascal (PSI) ; Johnston, Karl (CERN) ; Köster, Ulli (ILL) ; Müller, Cristina (PSI) ; Talip, Zeynep (PSI) ; van der Meulen, Nick (PSI)
CERN-INTC-2021-008 ; INTC-P-593.
- 2021.
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2 Favaretto, Chiara
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