CERN Accelerating science

Article
Title	Coherent Protein Dynamics Explored at FELIX
Author(s)	Austin, Robert
Affiliation	(PU, Princeton, New Jersey FOM Rijnhuizen, NieuwegeinOKSU-Phy, Stillwater - Oklahoma)
Publication	2004
In:	26th International Free Electron Laser Conference and 11th FEL User Workshop 2004, Trieste, Italy, 29 Aug - 3 Sep 2004, pp.e-proc. FRAOS04
Subject category	Accelerators and Storage Rings
Abstract	We have discovered that there exists a very narrow (less than 0.02 microns) wide resonance in the amide I band of myoglobin and photoactive yellow protein that can be driven to greater than 30% saturation using very narrow linewidth pump-probe spectroscopy at FELIX. The extraordinary narrowness of this transition and the extraordinary ease of saturation inplies that this band is highly anharmonic and decoupled from the other oscillators in the amide I band. We will present detailed measurments on this discovery and implications for energy flow in proteins.