| Article | |
| Title | Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure |
| Author(s) | Lau, Lawrence Chun Man (Hong Kong, Chinese U.) ; Lee, Wayne Yuk Wai (Hong Kong, Chinese U.) ; Butler, Anthony P H (Otago U. ; Canterbury U. ; CERN ; MARS Bioimaging) ; Chernoglazov, Alex I (MARS Bioimaging) ; Chung, Kwong Yin (Hong Kong, Chinese U.) ; Ho, Kevin Ki Wai (Hong Kong, Chinese U.) ; Grifth, James (Hong Kong, Chinese U.) ; Butler, Philip H (Canterbury U. ; CERN ; MARS Bioimaging) ; Yung, Patrick Shu Hang (Hong Kong, Chinese U.) |
| Publication | 2021 |
| Number of pages | 6 |
| In: | Sci. Rep. 11 (2021) 1554 |
| DOI | 10.1038/s41598-020-80463-2 |
| Subject category | Physics in General |
| Abstract | To determine whether state-of-the-art multi-energy spectral photon-counting computed tomography (MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted prosthesis [NexGen Legacy Posterior Stabilized (LPS) TKA] was analyzed as were pre-operative imaging examination and compared with a MARS-CT examination obtained of the extracted TKA prosthesis. Radiographs, fuoroscopy, ultrasound and MRI preoperatively did not reveal the cause of the implant failure. MARS CT images of the extracted prosthesis clearly showed the presence of posteromedial polyethylene and tibial tray wear which is compatible with the clinical appearance of the extracted TKA. MARS can identify polyethylene insert and metallic tibial tray wear as a cause of TKA failure, that could not be identifed with on standard pre-operative imaging. Although clinical MARS CT system is still under development, this case does illustrate its potential clinical usefulness. This is the frst study to document how MARS CT imaging can detect orthopedic implant failure not detected by standard current imaging techniques. This system has a potential clinical application in orthopedic patients. |
| Copyright/License | © 2021-2024 The Author(s) (License: CC-BY-4.0) |
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