User:Encore007/沙盒:修订间差异
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{{Drugbox
| Watchedfields = changed
| verifiedrevid = 464207742
| IUPAC_name = 2-(2-Oxopyrrolidin-1-yl)acetamide
| image = Piracetam.svg
| image2 = Piracetam ball-and-stick.png
| alt =
| caption =
<!--Clinical data-->
| tradename = Breinox, Dinagen, Lucetam, Nootropil, Nootropyl, Oikamid, Piracetam and many others
| Drugs.com = {{Drugs.com|international|piracetam}}
| legal_AU = Schedule 4
| legal_CA = Unscheduled
| legal_UK = POM
| legal_US_comment = Not permitted as drug or supplement
| routes_of_administration = By mouth, parenteral, or vaporized
<!--Pharmacokinetic data-->
| bioavailability = ~100%
| protein_bound =
| metabolism =
| elimination_half-life = 4–5小時
| excretion = 尿液
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|CAS}}
| CAS_number = 7491-74-9
| ATC_prefix = N06
| ATC_suffix = BX03
| PubChem = 4843
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4677
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = ZH516LNZ10
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D01914
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 36715
| IUPHAR_ligand = 4288
<!--Chemical data-->
| C=6 | H=10 | N=2 | O=2
| molecular_weight = 142.16 g/mol
| smiles = O=C1N(CC(=O)N)CCC1
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = GMZVRMREEHBGGF-UHFFFAOYSA-N
}}
{{medical}}
'''[[吡拉西坦]]'''(Piracetam) 是一種作為治療[[肌陣痛]]的[[藥物]]而上市的產品。<ref name="(eMC) 2017"/> 它也被用作[[Nootropic|認知增強劑]],以改善記憶、注意力和學習。<ref name=JAMA2019/><ref name="pmid9037245">{{cite journal | vauthors = Müller WE, Koch S, Scheuer K, Rostock A, Bartsch R | title = Piracetam對老齡化小鼠、大鼠和人類大腦膜流動性的影響 | journal = Biochemical Pharmacology | volume = 53 | issue = 2 | pages = 135–140 | date = 1997年1月 | pmid = 9037245 | doi = 10.1016/s0006-2952(96)00463-7 }}</ref><ref name="pmid26074758">{{cite journal | vauthors = Zhu D, Bungart BL, Yang X, Zhumadilov Z, Lee JC, Askarova S | title = 在阿茲海默症相關細胞途徑中膜生物物理學的作用 | journal = Frontiers in Neuroscience | volume = 9 | issue = | pages = 186 | date = 2015 | pmid = 26074758 | pmc = 4444756 | doi = 10.3389/fnins.2015.00186 | doi-access = free }}</ref><ref name="pmid826948">{{cite journal | vauthors = Dimond SJ, Brouwers EM | title = 通過藥物使用提高正常人類記憶力的能力 | journal = Psychopharmacology | volume = 49 | issue = 3 | pages = 307–309 | date = 1976年9月 | pmid = 826
'''吡拉西坦'''(Piracetam)是[[γ-丁内酰胺]]的衍生物。由Corneliu E. Giurgea于1950年代首次发现。在[[中国]],吡拉西坦作为药品的商品名有'''脑复康'''等。
在美国,[[美国食品药品监督管理局]]尚未核准吡拉西坦用在醫療用途上,也不允許作為[[營養補充品]]。<ref>{{Cite web |url=http://www.fda.gov/ICECI/EnforcementActions/WarningLetters/ucm225605.htm |title=Inspections, Compliance, Enforcement, and Criminal Investigations |accessdate=2017-11-11 |archive-date=2016-11-20 |archive-url=https://web.archive.org/web/20161120210431/http://www.fda.gov/ICECI/EnforcementActions/WarningLetters/ucm225605.htm |dead-url=no }}</ref><ref>{{Cite web |url=http://www.accessdata.fda.gov/scripts/enforcement/enforce_rpt-Product-Tabs.cfm?action=select&recall_number=D-194-2013&w=03202013&lang=eng |title=Enforcement Report - Week of 20 March 2013 |accessdate=2017-11-11 |archive-date=2016-04-30 |archive-url=https://web.archive.org/web/20160430043505/http://www.accessdata.fda.gov/scripts/enforcement/enforce_rpt-Product-Tabs.cfm?action=select&recall_number=D-194-2013&w=03202013&lang=eng |dead-url=no }}</ref>
==參考資料==
{{reflist}}
[[Category:乙酰胺]]
==参考文献==
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