There are several ways to disable and enable a particular widget in a Tkinter application. However, if we want to control the Tkinter window components such as mouse cursor, control icons, toolbars, then Tkinter provides several built-in functions which can be used to configure the Tkinter window objects.
To hide or disable the mouse pointer for a particular Tkinter application, then we can configure the mouse property using config(mouse= "none") method. It can be invoked for the master or root window.
Example
#Import tkinter library
from tkinter import *
from tkinter import ttk
#Create an instance of Tkinter frame or window
win= Tk()
#Set the geometry of tkinter frame
win.geometry("750x250")
def callback(event):
win.destroy()
#Create a Label and a Button widget
label=ttk.Label(win, text="Press Enter to Close the Window", font=('Century 17 bold'))
label.pack(ipadx=10)
win.bind('<Return>',callback)
#Disable the Mouse Pointer
win.config(cursor="none")
win.mainloop()Output
Running the above code will hide or disable the Mouse Pointer for the window.
Now, while residing in the window, press Enter that will force the window to close.