MySQL would return the output in time value after converting the difference between date-and-time values being provided to TIMEDIFF() function as arguments.
Example
mysql> Select TIMEDIFF('2017-10-22 04:05:45', '2017-10-21 03:04:44')AS 'Difference in Time';
+--------------------+
| Difference in Time |
+--------------------+
| 25:01:01 |
+--------------------+
1 row in set (0.00 sec)Here in this example, we can see that MySQL converts the difference in date-and-time values into time values and return the output in time value as well.