Pages that link to "Q6175781"
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The following pages link to Jeffery W. Kelly (Q6175781):
Displaying 50 items.
- Functional amyloid formation within mammalian tissue (Q21092782) (← links)
- Gelsolin domain 2 Ca2+ affinity determines susceptibility to furin proteolysis and familial amyloidosis of finnish type (Q24299113) (← links)
- Semen-derived amyloid fibrils drastically enhance HIV infection (Q24303668) (← links)
- Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis (Q24316177) (← links)
- The 8 and 5 kDa fragments of plasma gelsolin form amyloid fibrils by a nucleated polymerization mechanism, while the 68 kDa fragment is not amyloidogenic (Q24316253) (← links)
- Secretion of amyloidogenic gelsolin progressively compromises protein homeostasis leading to the intracellular aggregation of proteins (Q24338969) (← links)
- Structure-function-folding relationship in a WW domain (Q24550922) (← links)
- Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis (Q24615395) (← links)
- Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture (Q24626477) (← links)
- Evaluating beta-turn mimics as beta-sheet folding nucleators (Q24650580) (← links)
- Mechanism of Action and Clinical Application of Tafamidis in Hereditary Transthyretin Amyloidosis (Q26764754) (← links)
- Individual and collective contributions of chaperoning and degradation to protein homeostasis in E. coli (Q27320857) (← links)
- NMR solution structure of the isolated Apo Pin1 WW domain: comparison to the x-ray crystal structures of Pin1 (Q27637271) (← links)
- Determinants for Dephosphorylation of the RNA Polymerase II C-Terminal Domain by Scp1 (Q27640445) (← links)
- Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action (Q27641464) (← links)
- Antibody domain exchange is an immunological solution to carbohydrate cluster recognition (Q27641517) (← links)
- ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization (Q27641993) (← links)
- Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization (Q27642438) (← links)
- Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis (Q27642917) (← links)
- Human-murine transthyretin heterotetramers are kinetically stable and non-amyloidogenic. A lesson in the generation of transgenic models of diseases involving oligomeric proteins (Q27649069) (← links)
- Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors (Q27649376) (← links)
- Structural insight into pH-induced conformational changes within the native human transthyretin tetramer (Q27651370) (← links)
- Toward Optimization of the Linker Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies † (Q27652272) (← links)
- Toward Optimization of the Second Aryl Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies † (Q27653642) (← links)
- A Substructure Combination Strategy To Create Potent and Selective Transthyretin Kinetic Stabilizers That Prevent Amyloidogenesis and Cytotoxicity (Q27658823) (← links)
- Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma (Q27659009) (← links)
- Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding (Q27660153) (← links)
- Potent Kinetic Stabilizers That Prevent Transthyretin-Mediated Cardiomyocyte Proteotoxicity (Q27671971) (← links)
- Binding of 3,4,5,6-Tetrahydroxyazepanes to the Acid-β-glucosidase Active Site: Implications for Pharmacological Chaperone Design for Gaucher Disease (Q27675348) (← links)
- Dissecting the structure, thermodynamic stability, and aggregation properties of the A25T transthyretin (A25T-TTR) variant involved in leptomeningeal amyloidosis: identifying protein partners that co-aggregate during A25T-TTR fibrillogenesis in [...] (Q27675618) (← links)
- Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate (Q27675997) (← links)
- AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin (Q27678369) (← links)
- Structural and Energetic Basis of Carbohydrate–Aromatic Packing Interactions in Proteins (Q27678514) (← links)
- Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade (Q27679360) (← links)
- Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors (Q27679824) (← links)
- Stilbene Vinyl Sulfonamides as Fluorogenic Sensors of and Traceless Covalent Kinetic Stabilizers of Transthyretin That Prevent Amyloidogenesis (Q27680500) (← links)
- Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts (Q27681967) (← links)
- Adapting proteostasis for disease intervention (Q28131818) (← links)
- Understanding the mechanism of beta-sheet folding from a chemical and biological perspective (Q28296428) (← links)
- Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis (Q28472162) (← links)
- Biochemical properties of highly neuroinvasive prion strains (Q28480480) (← links)
- Opposing activities protect against age-onset proteotoxicity (Q29619758) (← links)
- Reduced IGF-1 signaling delays age-associated proteotoxicity in mice (Q30497845) (← links)
- Bisaryloxime ethers as potent inhibitors of transthyretin amyloid fibril formation (Q30779129) (← links)
- Tuning the free-energy landscape of a WW domain by temperature, mutation, and truncation (Q30902216) (← links)
- Solid-phase synthesis and stereochemical assignments of tenuecyclamides A-D employing heterocyclic amino acids derived from commercially available Fmoc alpha-amino acids (Q33204777) (← links)
- The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation (Q33272109) (← links)
- Influence of hPin1 WW N-terminal domain boundaries on function, protein stability, and folding (Q33288606) (← links)
- Fourier transform infrared spectroscopy provides a fingerprint for the tetramer and for the aggregates of transthyretin (Q33435248) (← links)
- Tafamidis for transthyretin familial amyloid polyneuropathy: a randomized, controlled trial (Q33903527) (← links)