Rab5 is required in metastatic cancer cells for Caveolin-1-enhanced Rac1 activation, migration and invasion. (Q41432611)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Rab5 is required in metastatic cancer cells for Caveolin-1-enhanced Rac1 activation, migration and invasion (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

Jorge Díaz

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Pablo Mendoza

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Rina Ortiz

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Natalia Díaz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Lisette Leyton

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Dwayne Stupack

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Andrew F G Quest

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

language of work or name

English

0 references

publication date

21 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

number of pages

6

1 reference

inferred from page(s)

published in

Journal of Cell Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

127

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

Pt 11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

2401-2406

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

12 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4074264/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Cavin-1 is essential for the tumor-promoting effect of caveolin-1 and enhances its prognostic potency in pancreatic cancer.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Pilus phase variation switches gonococcal adherence to invasion by caveolin-1-dependent host cell signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

E-cadherin determines Caveolin-1 tumor suppression or metastasis enhancing function in melanoma cells.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

The caveolin-1 connection to cell death and survival

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Tiam1, overexpressed in most malignancies, is a novel tumor biomarker

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Rab5A is associated with axillary lymph node metastasis in breast cancer patients

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Rab5 in the regulation of cell motility and invasion.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Overexpression of T lymphoma invasion and metastasis 1 predict renal cell carcinoma metastasis and overall patient survival

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Rab5 mediates caspase-8-promoted cell motility and metastasis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Rab GTPases as coordinators of vesicle traffic

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Caspase 8 promotes peripheral localization and activation of Rab5.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Caveolin-1: an ambiguous partner in cell signalling and cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

E-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced beta-catenin-Tcf/Lef-dependent transcription

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Identification of a novel domain at the N terminus of caveolin-1 that controls rear polarization of the protein and caveolae formation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

The p85alpha subunit of phosphatidylinositol 3'-kinase binds to and stimulates the GTPase activity of Rab proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Rab5 induces Rac-independent lamellipodia formation and cell migration

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Caveolin-1 levels are down-regulated in human colon tumors, and ectopic expression of caveolin-1 in colon carcinoma cell lines reduces cell tumorigenicity.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

The GTPase-activating protein RN-tre controls focal adhesion turnover and cell migration

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Gene expression patterns in melanocytic cells: candidate markers for early stage and malignant transformation.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074264

Caveolin-1 expression in clinically confined human prostate cancer: a novel prognostic marker

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24659799

12 December 2020

inferred from PubMed ID database lookup

Prognostic relevance of increased Rac GTPase expression in prostate carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24659799

12 December 2020

inferred from PubMed ID database lookup

Caveolin-1 activates Rab5 and enhances endocytosis through direct interaction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24659799

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1242/JCS.141689

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

24659799

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24659799%20AND%20SRC:MED&resulttype=core&format=json