Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes (Q40663965)

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scientific article published on 13 March 2003

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English	Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes	scientific article published on 13 March 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 September 2017

Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes (English)

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Europe PubMed Central

PubMed publication ID

22 September 2017

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Gary M Wildey

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Supriya Patil

2

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Europe PubMed Central

PubMed publication ID

22 September 2017

Philip H Howe

3

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Europe PubMed Central

PubMed publication ID

22 September 2017

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publication date

13 March 2003

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Europe PubMed Central

PubMed publication ID

22 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

22 September 2017

278

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Europe PubMed Central

PubMed publication ID

22 September 2017

20

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

18069-18077

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

TGF-beta signal transduction

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21 January 2018

Regulation of Smad activity

1 reference

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21 January 2018

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

1 reference

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21 January 2018

Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.

1 reference

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21 January 2018

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

1 reference

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Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2

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Transforming growth factor beta activation of p44mapk in proliferating cultures of epithelial cells

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21 January 2018

TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway

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21 January 2018

ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling

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21 January 2018

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

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21 January 2018

RhoB is stabilized by transforming growth factor beta and antagonizes transcriptional activation

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21 January 2018

Extracellular signal-regulated kinase and the small GTP-binding protein, Rac, contribute to the effects of transforming growth factor-beta1 on gene expression

1 reference

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Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

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21 January 2018

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1

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21 January 2018

Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells

1 reference

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21 January 2018

TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha

1 reference

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21 January 2018

Transforming growth factor beta induces caspase 3-independent cleavage of alphaII-spectrin (alpha-fodrin) coincident with apoptosis

1 reference

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21 January 2018

Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosis

1 reference

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21 January 2018

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

1 reference

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21 January 2018

A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif

1 reference

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21 January 2018

Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells

1 reference

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21 January 2018

Bim: a novel member of the Bcl-2 family that promotes apoptosis

1 reference

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21 January 2018

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

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21 January 2018

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

1 reference

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21 January 2018

Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family

1 reference

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21 January 2018

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

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21 January 2018

Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim

1 reference

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21 January 2018

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

1 reference

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21 January 2018

The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells

1 reference

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21 January 2018

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

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21 January 2018

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 reference

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21 January 2018

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

1 reference

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21 January 2018

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

1 reference

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

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Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

1 reference

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Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

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The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

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FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

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Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cells

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Smad7 is an activin-inducible inhibitor of activin-induced growth arrest and apoptosis in mouse B cells

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Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells

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LY294002-mediated inhibition of phosphatidylinositol 3-kinase activity triggers growth inhibition and apoptosis in CD40-triggered Ramos-Burkitt lymphoma B cells

1 reference

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Critical role of Smads and AP-1 complex in transforming growth factor-beta -dependent apoptosis

1 reference

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Smad4 and FAST-1 in the assembly of activin-responsive factor

1 reference

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Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

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1 reference

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Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim

1 reference

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Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

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10.1074/JBC.M211958200

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Europe PubMed Central

PubMed publication ID

22 September 2017

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https://api.fatcat.wiki/v0/release/qppoa5qvzjgyfp2kv4epmbwuce

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22 September 2017

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