Pages that link to "Q24651926"
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The following pages link to PDE4 inhibitors: current status (Q24651926):
Displaying 50 items.
- Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs (Q21089606) (← links)
- Phosphodiesterase 4-targeted treatments for autoimmune diseases (Q21245284) (← links)
- Can the anti-inflammatory potential of PDE4 inhibitors be realized: guarded optimism or wishful thinking? (Q24651941) (← links)
- Synthesis, Pharmacological Profile and Docking Studies of New Sulfonamides Designed as Phosphodiesterase-4 Inhibitors (Q27322207) (← links)
- Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety (Q27658795) (← links)
- Phosphodiesterases as therapeutic targets for Alzheimer's disease (Q28279704) (← links)
- Phosphodiesterase-4 Inhibition Combined with Isoniazid Treatment of Rabbits with Pulmonary Tuberculosis Reduces Macrophage Activation and Lung Pathology (Q28389823) (← links)
- Successful shortening of tuberculosis treatment using adjuvant host-directed therapy with FDA-approved phosphodiesterase inhibitors in the mouse model (Q28480511) (← links)
- Differential expression of cyclic nucleotide phosphodiesterases 4 in developing rat lung (Q28579991) (← links)
- Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene (Q28943322) (← links)
- Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay (Q30466708) (← links)
- PDE8 regulates rapid Teff cell adhesion and proliferation independent of ICER. (Q30987183) (← links)
- Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials (Q33498278) (← links)
- A large-scale chemical screen for regulators of the arginase 1 promoter identifies the soy isoflavone daidzeinas a clinically approved small molecule that can promote neuronal protection or regeneration via a cAMP-independent pathway (Q33523661) (← links)
- Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophages (Q33564601) (← links)
- Enhancement of the anti-inflammatory and anti-arthritic effects of theophylline by a low dose of a nitric oxide donor or non-specific nitric oxide synthase inhibitor (Q33569575) (← links)
- From synapse to nucleus: novel targets for treating depression (Q33653177) (← links)
- The inhaled phosphodiesterase 4 inhibitor GSK256066 reduces allergen challenge responses in asthma (Q33737175) (← links)
- Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis (Q33799668) (← links)
- Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion (Q33903491) (← links)
- No relevant cardiac, pharmacokinetic or safety interactions between roflumilast and inhaled formoterol in healthy subjects: an open-label, randomised, actively controlled study (Q33919207) (← links)
- Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis (Q34091087) (← links)
- Repurposing human PDE4 inhibitors for neglected tropical diseases: design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitors (Q34138086) (← links)
- Unraveling the Genetic Basis of Asthma and Allergic Diseases (Q34159892) (← links)
- Exposing rodents to a combination of tobacco smoke and lipopolysaccharide results in an exaggerated inflammatory response in the lung (Q34219585) (← links)
- The in vivo efficacy and side effect pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long-acting β 2-adrenoceptor agonist in preclinical animal species (Q34292566) (← links)
- Phosphodiesterase 4B is essential for TH2-cell function and development of airway hyperresponsiveness in allergic asthma (Q34409716) (← links)
- The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma (Q34491824) (← links)
- Inhibition of cyclooxygenase‐2 prevents adverse effects induced by phosphodiesterase type 4 inhibitors in rats (Q34540209) (← links)
- S-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway (Q34868229) (← links)
- Roflumilast inhibits lipopolysaccharide-induced tumor necrosis factor-α and chemokine production by human lung parenchyma (Q34997388) (← links)
- Panax ginseng C.A Meyer root extract for moderate chronic obstructive pulmonary disease (COPD): study protocol for a randomised controlled trial (Q35147449) (← links)
- Maternal exposure to secondhand cigarette smoke primes the lung for induction of phosphodiesterase-4D5 isozyme and exacerbated Th2 responses: rolipram attenuates the airway hyperreactivity and muscarinic receptor expression but not lung inflammation (Q35327025) (← links)
- Phosphodiesterase-4D Knock-down in the Prefrontal Cortex Alleviates Chronic Unpredictable Stress-Induced Depressive-Like Behaviors and Memory Deficits in Mice (Q35838089) (← links)
- Roflumilast inhibits the release of chemokines and TNF-α from human lung macrophages stimulated with lipopolysaccharide (Q36025380) (← links)
- Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. (Q36061710) (← links)
- PDE4 inhibition suppresses IL-17-associated immunity in dry eye disease (Q36122993) (← links)
- Inhibition of chlorine-induced lung injury by the type 4 phosphodiesterase inhibitor rolipram (Q36173928) (← links)
- Gene Set Enrichment Analysis Unveils the Mechanism for the Phosphodiesterase 4B Control of Glucocorticoid Response in B-cell Lymphoma (Q36295294) (← links)
- Traumatic Brain Injury Upregulates Phosphodiesterase Expression in the Hippocampus. (Q36548551) (← links)
- RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects. (Q36781079) (← links)
- The cyclic AMP signaling pathway: Exploring targets for successful drug discovery (Review). (Q36817378) (← links)
- Monomethylated-adenines potentiate glucose-induced insulin production and secretion via inhibition of phosphodiesterase activity in rat pancreatic islets. (Q36930349) (← links)
- Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1. (Q37046760) (← links)
- Differential Expression and Function of PDE8 and PDE4 in Effector T cells: Implications for PDE8 as a Drug Target in Inflammation. (Q37195453) (← links)
- Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory. (Q37198415) (← links)
- Rational combined targeting of phosphodiesterase 4B and SYK in DLBCL (Q37234623) (← links)
- Less is more: reducing the reliance on animal models for nausea and vomiting research (Q37332614) (← links)
- Opportunities for the replacement of animals in the study of nausea and vomiting (Q37332618) (← links)
- New treatments for chronic obstructive pulmonary disease and viable formulation/device options for inhalation therapy (Q37532557) (← links)