The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis (Q39738345)

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Language	Label	Description	Also known as
English	The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

0 references

rheumatoid arthritis

1 reference

based on heuristic

inferred from title

prostaglandin E2

1 reference

based on heuristic

inferred from title

author name string

Jennifer M McCoy

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Joan R Wicks

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Laurent P Audoly

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

0 references

publication date

1 September 2002

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

110

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

651-658

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Prostaglandin E(2) regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Prostanoid receptors: subtypes and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Induction of IL-6 via the EP3 subtype of prostaglandin E receptor in rat adjuvant-arthritic synovial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Up-regulation of prostaglandin E receptor EP2 and EP4 subtypes in rat synovial tissues with adjuvant arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Involvement of IL-6, apart from its role in immunity, in mediating a chronic response during experimental arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Macrophages in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Comparison of agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: role of the carboxyl terminus in EP4 receptor sequestration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Impaired bone resorption by lipopolysaccharide in vivo in mice deficient in the prostaglandin E receptor EP4 subtype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Impaired bone resorption to prostaglandin E2 in prostaglandin E receptor EP4-knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Regulation of inflammation by collagen-binding integrins alpha1beta1 and alpha2beta1 in models of hypersensitivity and arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Regulation of inflammatory responses by oncostatin M

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Urinary concentrating function in mice lacking EP3 receptors for prostaglandin E2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Interleukin 6 plays a key role in the development of antigen-induced arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Interleukin 6 is required for the development of collagen-induced arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E2 inhibits lipopolysaccharide-induced tumour necrosis factor-alpha generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Interleukin-6 and the acute phase response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

The Role of Arachidonic Acid Oxygenation Products in Pain and Inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

14 September 2017

Characterization of the LPS-stimulated expression of EP2 and EP4 prostaglandin E receptors in mouse macrophage-like cell line, J774.1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

25 September 2017

Comparison of in vivo effects of human recombinant IL 1 and human recombinant IL 6 in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

25 September 2017

Joint destruction in rheumatoid arthritis: biological bases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

17 June 2018

Characterization of the PGE2 receptor subtype in bovine chondrocytes in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

17 June 2018

Suppression of acute and chronic inflammation in adrenalectomized rats by pharmacologic amounts of prostaglandins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

17 June 2018

Interleukin 6, the third mediator of acute-phase reaction, modulates hepatic protein synthesis in human and mouse. Comparison with interleukin 1 beta and tumor necrosis factor-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

17 June 2018

The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

17 June 2018

Characterization of PGE(2) receptors (EP) and their role as mediators of 1alpha,25-(OH)(2)D(3) effects on growth zone chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

20 August 2018

Involvement of prostaglandin E(2) in interleukin-1alpha-induced parathyroid hormone-related peptide production in synovial fibroblasts of patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151107

20 August 2018

The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of prostanoid receptors in hepatocytes, Kupffer cells, sinusoidal endothelial cells and stellate cells of rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of collagenase-induced damage of collagen by 9A4, a monoclonal C-terminal neoepitope antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Prostaglandin E1 on Adjuvant Arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levels of prostaglandins F2 alpha and E2 and thromboxane B2 in joint fluid in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of prostaglandins from rheumatoid synovium in inhibition of articular cartilage metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of prostaglandin E2 on adult pig articular cartilage slices in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concentrations of prostaglandins D2, E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 in synovial fluid from patients with inflammatory joint disorders and osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagen-induced arthritis in mice: synergistic effect of E. coli lipopolysaccharide bypasses epitope specificity in the induction of arthritis with monoclonal antibodies to type II collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two Gs-coupled prostaglandin E receptor subtypes, EP2 and EP4, differ in desensitization and sensitivity to the metabolic inactivation of the agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum amyloid A in the assessment of early inflammatory arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction by interleukin 6 of Gs-coupled prostaglandin E2 receptors in rat hepatocytes mediating a prostaglandin E2–dependent inhibition of the hepatocyte's acute phase response

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cartilage damage after intraarticular exposure to collagenase 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI0215528

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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