Concepts in gene therapy for cartilage repair. (Q37099568)

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scientific article published on April 2008

Language	Label	Description	Also known as
English	Concepts in gene therapy for cartilage repair.	scientific article published on April 2008

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313477%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

Europe PubMed Central

Concepts in gene therapy for cartilage repair (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313477%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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based on heuristic

inferred from title

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3 January 2020

author name string

Ulrich Nöth

2

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Europe PubMed Central

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3 January 2020

Rocky S Tuan

3

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3 January 2020

publication date

1 April 2008

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3 January 2020

1 reference

Europe PubMed Central

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3 January 2020

39 Suppl 1

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3 January 2020

S97-113

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3 January 2020

Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells

1 reference

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Technology Insight: adult stem cells in cartilage regeneration and tissue engineering

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Evidence of calcium-dependent pathway in the regulation of human beta1,3-glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis

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Mesenchymal stem cells as trophic mediators

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Ex vivo gene therapy approaches to cartilage repair

1 reference

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Gene therapeutic approaches-transfer in vivo

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Cartilage tissue engineering: its potential and uses

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Cartilage repair: generations of autologous chondrocyte transplantation

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Gene therapy for cartilage defects

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Gene transfer to human joints: progress toward a gene therapy of arthritis

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Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repair

1 reference

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Cellular lifespan and senescence signaling in embryonic stem cells

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Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development

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Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms

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Regional gene therapy to enhance bone repair

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Osteoarthritis gene therapy

1 reference

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Gene-based approaches for the repair of articular cartilage

1 reference

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A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer

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14 September 2017

Current state of cartilage tissue engineering

1 reference

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Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk

1 reference

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14 September 2017

Gene therapy for arthritis

1 reference

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Progress and problems with the use of viral vectors for gene therapy

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Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees

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Stem cells as platforms for delivery of genes to enhance cartilage repair.

1 reference

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Adult mesenchymal stem cells and cell-based tissue engineering

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Clinical applications of growth factors for articular cartilage repair

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Pluripotency of mesenchymal stem cells derived from adult marrow

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Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects

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BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation

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BMP signaling pathways in cartilage and bone formation

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L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway

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Interaction of growth factors regulating chondrocyte differentiation in the developing embryo.

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Microfracture: surgical technique and rehabilitation to treat chondral defects.

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Differences in repair responses between immature and mature cartilage

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Mesenchymal stem cells: building blocks for molecular medicine in the 21st century

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BMP-2 induction and TGF-beta 1 modulation of rat periosteal cell chondrogenesis

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Vector systems for gene transfer to joints

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Cbfa1 is a positive regulatory factor in chondrocyte maturation

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Mechanisms of chondrocyte apoptosis

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The role of nitric oxide in articular cartilage damage

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Multilineage potential of adult human mesenchymal stem cells

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Long-term results of rib perichondrial grafts for repair of cartilage defects in the human knee

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Current concepts in the treatment of articular cartilage defects

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Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA.

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Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer

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Adenovirus mediated BMP-13 gene transfer induces chondrogenic differentiation of murine mesenchymal progenitor cells

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Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGF-β-mediated chondrocyte proliferation and proteoglycan synthesis

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Chondrogenic differentiation of mesenchymal progenitor cells encapsulated in ultrahigh-viscosity alginate.

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29 September 2017

Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium

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Wnt-3A enhances bone morphogenetic protein-2-mediated chondrogenesis of murine C3H10T1/2 mesenchymal cells

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29 September 2017

The T-box transcription factor Brachyury mediates cartilage development in mesenchymal stem cell line C3H10T1/2.

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29 September 2017

Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene

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29 September 2017

Efficient chondrogenic differentiation of mesenchymal cells in micromass culture by retroviral gene transfer of BMP-2.

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29 September 2017

Intra-articular delivery of a herpes simplex virus IL-1Ra gene vector reduces inflammation in a rabbit model of arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

29 September 2017

Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

29 September 2017

Adenovirus vector-mediated gene transduction to chondrocytes: in vitro evaluation of therapeutic efficacy of transforming growth factor-beta 1 and heat shock protein 70 gene transduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

29 September 2017

A 47-bp sequence of the first intron of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte Expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

29 September 2017

Inhibition of transfer of collagen-induced arthritis into SCID mice by ex vivo infection of spleen cells with retroviruses expressing soluble tumor necrosis factor receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

29 September 2017

Selenium supplementation restores the antioxidative capacity and prevents cell damage in bone marrow stromal cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein-7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Inhibition of cartilage degradation: a combined tissue engineering and gene therapy approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Overexpression of human insulin-like growth factor-I promotes new tissue formation in an ex vivo model of articular chondrocyte transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Regeneration of hyaline cartilage by cell-mediated gene therapy using transforming growth factor beta 1-producing fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Differential effects of IL-8, LIF (pro-inflammatory) and IL-11 (anti-inflammatory) on TNF-alpha-induced PGE(2)release and on signalling pathways in human OA synovial fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Age-dependent effects of hedgehog protein on chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Stable transfection of human fetal chondrocytes with a type II procollagen minigene: expression of the mutant protein and alterations in the structure of the extracellular matrix in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Adenovirus mediated gene delivery to the joints of guinea pigs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Resurfacing of articular cartilage explants with genetically-modified human chondrocytes in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Interleukin-4 and interleukin-10 are chondroprotective and decrease mononuclear cell recruitment in human rheumatoid synovium in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

In vivo direct gene transfer into articular cartilage by intraarticular injection mediated by HVJ (Sendai virus) and liposomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Differential effects of parathyroid hormone fragments on collagen gene expression in chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Differentiation-dependent effects of IL-1 and TGF-beta on human articular chondrocyte proliferation are related to inducible nitric oxide synthase expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Insulin-like growth factor 1 can decrease degradation and promote synthesis of proteoglycan in cartilage exposed to cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

27 June 2018

Stemming cartilage degeneration: adult mesenchymal stem cells as a cell source for articular cartilage tissue engineering.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Regional gene therapy for full-thickness articular cartilage lesions using naked DNA with a collagen matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Transgene-activated mesenchymal cells for articular cartilage repair: a comparison of primary bone marrow-, perichondrium/periosteum- and fat-derived cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Optimization of high-efficiency transfection of adult human mesenchymal stem cells in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Retroviral transduction with SOX9 enhances re-expression of the chondrocyte phenotype in passaged osteoarthritic human articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Autologous bone marrow stromal cell transplantation for repair of full-thickness articular cartilage defects in human patellae: two case reports.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Targeted expression of SHH affects chondrocyte differentiation, growth plate organization, and Sox9 expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Enhanced repair of the anterior cruciate ligament by in situ gene transfer: evaluation in an in vitro model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Repair of articular cartilage defects in rabbits using CDMP1 gene-transfected autologous mesenchymal cells derived from bone marrow.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Transduction of passaged human articular chondrocytes with adenoviral, retroviral, and lentiviral vectors and the effects of enhanced expression of SOX9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Overexpression of human fibroblast growth factor 2 stimulates cell proliferation in an ex vivo model of articular chondrocyte transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Adenovirus-mediated gene transfer of glutamine: fructose-6-phosphate amidotransferase antagonizes the effects of interleukin-1beta on rat chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Gene delivery to cartilage defects using coagulated bone marrow aspirate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Retroviral delivery of Noggin inhibits the formation of heterotopic ossification induced by BMP-4, demineralized bone matrix, and trauma in an animal model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Sustained transgene expression in cartilage defects in vivo after transplantation of articular chondrocytes modified by lipid-mediated gene transfer in a gel suspension delivery system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Lentiviral-mediated gene delivery to synovium: potent intra-articular expression with amplification by inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Runx2 expression and action in chondrocytes are regulated by retinoid signaling and parathyroid hormone-related peptide (PTHrP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Tetracycline-inducible interleukin-10 gene transfer mediated by an adeno-associated virus: application to experimental arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Boning up on telomerase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Delivery of plasmid DNA to articular chondrocytes via novel collagen-glycosaminoglycan matrices.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Isolation and characterization of rapidly self-renewing stem cells from cultures of human marrow stromal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

In vivo gene delivery to synovium by lentiviral vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Insulin-like growth factor-I enhances cell-based repair of articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

In vitro engineered cartilage constructs produced by press-coating biodegradable polymer with human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Autologous chondrocyte transplantation. Biomechanics and long-term durability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Chondrocytic differentiation of mesenchymal stem cells sequentially exposed to transforming growth factor-beta1 in monolayer and insulin-like growth factor-I in a three-dimensional matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Exogenous insulin-like growth factor-I stimulates an autoinductive IGF-I autocrine/paracrine response in chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Effects of cartilage-derived morphogenetic proteins and osteogenic protein-1 on osteochondrogenic differentiation of periosteum-derived cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Direct gene delivery strategies for the treatment of rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Cartilage and bone regeneration using gene-enhanced tissue engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Mesenchymal stem cells and gene therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Platelet-derived growth factor A modulates limb chondrogenesis both in vivo and in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Genetic enhancement of matrix synthesis by articular chondrocytes: comparison of different growth factor genes in the presence and absence of interleukin-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Efficient lipid-mediated gene transfer to articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Interaction of Ihh and BMP/Noggin signaling during cartilage differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Expression of human bone morphogenic protein 7 in primary rabbit periosteal cells: potential utility in gene therapy for osteochondral repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Inhibition of tumor necrosis factor alpha-induced prostaglandin E2 production by the antiinflammatory cytokines interleukin-4, interleukin-10, and interleukin-13 in osteoarthritic synovial fibroblasts: distinct targeting in the signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Articular cartilage: injuries and potential for healing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

FGF signaling in skeletal development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Differential effects of IGF-1 and TGF beta-2 on the assembly of proteoglycans in pericellular and territorial matrix by cultured bovine articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Regulatory activities of the 5'- and 3'-untranslated regions and promoter of the human aggrecan gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Transplantation of adenovirally transduced allogeneic chondrocytes into articular cartilage defects in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714368

3 September 2018

Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microfracture to treat full-thickness chondral defects: surgical technique, rehabilitation, and outcomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Indications and implementation of recommendations of the working group "Tissue Regeneration and Tissue Substitutes" for autologous chondrocyte transplantation (ACT)]

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of mechanical trauma on matrix and cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased matrix synthesis following adenoviral transfer of a transforming growth factor beta1 gene into articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibroblast-mediated delivery of growth factor complementary DNA into mouse joints induces chondrogenesis but avoids the disadvantages of direct viral gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of transforming growth factor-β and epidermal growth factor on the cell cycle of cultured rabbit articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ex vivo gene transfer to chondrocytes in full-thickness articular cartilage defects: a feasibility study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experimental osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined effects of insulin-like growth factor-1 and transforming growth factor-beta1 on periosteal mesenchymal cells during chondrogenesis in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte growth factor facilitates cartilage repair. Full thickness articular cartilage defect studied in rabbit knees

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Articular cartilage repair and transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of growth factors in rabbit articular cartilage repair by chondrocytes in agarose

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advanced techniques in autologous chondrocyte transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repair of articular cartilage defects one year after treatment with recombinant human bone morphogenetic protein-2 (rhBMP-2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin composites

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Principles of cartilage repair and regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chondrogenic Differentiation of Mesenchymal Stem Cells from Bone Marrow: Differentiation-Dependent Gene Expression of Matrix Components

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-mediated gene transfer to healing tendon--enhanced efficiency using a gelatin sponge

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of chondrocyte apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cartilage injury induces chondrocyte apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of osteochondritis dissecans of the knee with autologous chondrocyte transplantation: results at two to ten years

1 reference

https://pubmed.ncbi.nlm.nih.gov/18313477

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.INJURY.2008.01.034

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313477%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313477%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313477%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

ResearchGate publication ID

0 references

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