Regulation of bone mass by Wnt signaling (Q34576629)

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scientific article

Language	Label	Description	Also known as
English	Regulation of bone mass by Wnt signaling	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1 reference

Europe PubMed Central

Regulation of bone mass by Wnt signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Ormond Macdougald

3

object named as

Ormond A Macdougald

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Venkatesh Krishnan

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Henry U Bryant

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

0 references

publication date

1 May 2006

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

116

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1202-1209

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo

1 reference

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Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B.

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Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice

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Osteoclasts from patients with autosomal dominant osteopetrosis type I caused by a T253I mutation in low-density lipoprotein receptor-related protein 5 are normal in vitro, but have decreased resorption capacity in vivo

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Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.

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Wnt signalling pathway: a new target for the treatment of osteoporosis

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The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis

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TAZ, a transcriptional modulator of mesenchymal stem cell differentiation

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Distinct effects of PPARgamma insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells

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How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow

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Effects of parathyroid hormone on Wnt signaling pathway in bone

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Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling

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SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

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Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

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Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

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Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

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Wnt signalling in stem cells and cancer

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Essential role of beta-catenin in postnatal bone acquisition

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Wnt5b partially inhibits canonical Wnt/beta-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes

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Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

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Gene array analysis of Wnt-regulated genes in C3H10T1/2 cells

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Regulation of osteoblastogenesis and bone mass by Wnt10b

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Glucocorticoid suppresses the canonical Wnt signal in cultured human osteoblasts.

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Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway.

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Secreted frizzled-related protein 1 modulates glucocorticoid attenuation of osteogenic activities and bone mass

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Sequential roles of Hedgehog and Wnt signaling in osteoblast development

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Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6

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Secreted frizzled-related protein-1 inhibits RANKL-dependent osteoclast formation.

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Wnt signaling in osteoblasts and bone diseases

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The Wnt signaling pathway in development and disease

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WNT and beta-catenin signalling: diseases and therapies

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The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd.

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PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

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The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice

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BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop

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Notch 1 impairs osteoblastic cell differentiation

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Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

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High bone mass in mice expressing a mutant LRP5 gene

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Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro

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Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density

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Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors

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Mechanisms of glucocorticoid action in bone

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Regulation of Wnt signaling during adipogenesis

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Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

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Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation

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High bone density due to a mutation in LDL-receptor-related protein 5

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Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis

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Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

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LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development

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Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism

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Requirement for beta-catenin in anterior-posterior axis formation in mice

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beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion

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Wnt signaling: a common theme in animal development

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Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

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Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

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Lack of beta-catenin affects mouse development at gastrulation

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Oral salmon calcitonin induced suppression of urinary collagen type II degradation in postmenopausal women: a new potential treatment of osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1451219

27 October 2018

Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1451219

27 October 2018

Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1451219

27 October 2018

Wnt10b inhibits development of white and brown adipose tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1451219

27 October 2018

Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: novel mechanism of glucocorticoid-induced osteoporosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1451219

27 October 2018

MSX2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1451219

27 October 2018

Wnt signaling controls the phosphorylation status of beta-catenin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1451219

27 October 2018

Cancer morbidity in psychiatric patients: influence of lithium carbonate treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1451219

27 October 2018

Interconversion potential of cloned human marrow adipocytes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16670761

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stem cell characteristics of human trabecular bone-derived cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16670761

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI28551

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

0 references

Sitelinks

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