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    Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-[2-methoxy-1(R)-4-(trifluoromethyl)phenyl]ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist (English)
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    Jayaram R Tagat
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    Stuart W McCombie
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    Dennis Nazareno
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    Marc A Labroli
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    Yushi Xiao
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    Ruo W Steensma
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    Julie M Strizki
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    Bahige M Baroudy
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    Kathleen Cox
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    Jean Lachowicz
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    Geoffrey Varty
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    Robert Watkins
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    6 May 2004
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    47
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    10
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    2405-8
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