Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles (Q73085036)

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1 November 2019

title

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles (English)

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1 November 2019

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J C Brüning

1

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1 November 2019

J Winnay

2

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1 November 2019

S Bonner-Weir

3

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1 November 2019

S I Taylor

4

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1 November 2019

D Accili

5

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C R Kahn

6

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1 November 2019

language of work or name

English

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publication date

1 February 1997

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1 November 2019

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1 November 2019

volume

88

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1 November 2019

issue

4

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1 November 2019

page(s)

561-572

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Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Compensatory Growth of Pancreatic -Cells in Adult Rats After Short-Term Glucose Infusion

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Insulin receptor substrate-1 variants in non-insulin-dependent diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

4PS/insulin receptor substrate (IRS)-2 is the alternative substrate of the insulin receptor in IRS-1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Heterogeneity in Pancreatic β-cell Population

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Insulin binding, internalization, and insulin receptor regulation in fibroblasts from type II, non-insulin-dependent diabetic subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Mapping genes in diabetes. Genetic epidemiological perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Insulin receptor substrate 1 is required for insulin-mediated mitogenic signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Insulin-receptor kinase activity of adipose tissue from morbidly obese humans with and without NIDDM.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Role of IRS-2 in insulin and cytokine signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Lilly Lecture: molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Molecular scanning of the insulin receptor substrate-1 (IRS-1) gene in Japanese patients with NIDDM: identification of five novel polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Homozygous deletion of the human insulin receptor gene results in leprechaunism

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981896-6

7 January 2021

10.1016/S0092-8674(00)81896-6

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1 November 2019

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