Antisense and ribozyme constructs in transgenic animals (Q40923006)

24 September 2017

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title

Antisense and ribozyme constructs in transgenic animals (English)

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24 September 2017

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D L Sokol

1

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24 September 2017

J D Murray

series ordinal

2

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24 September 2017

publication date

1 November 1996

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24 September 2017

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24 September 2017

volume

5

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24 September 2017

issue

6

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24 September 2017

page(s)

363-371

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Determinants and regulation of cytoplasmic mRNA stability in eukaryotic cells

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF01980201

Determinants that contribute to cytoplasmic stability of human c-fos and beta-globin mRNAs are located at several sites in each mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01980201

N-myc mRNA forms an RNA-RNA duplex with endogenous antisense transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01980201

Transgenic mice with antisense RNA against the nucleocapsid protein mRNA of mouse hepatitis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01980201

Expression of chimeric tRNA-driven antisense transcripts renders NIH 3T3 cells highly resistant to Moloney murine leukemia virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01980201

The in vivo application of ribozymes

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Stable reduction of thymidine kinase activity in cells expressing high levels of anti-sense RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Incorporation of the catalytic domain of a hammerhead ribozyme into antisense RNA enhances its inhibitory effect on the replication of human immunodeficiency virus type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Modulation of eukaryotic gene expression by complementary RNA or DNA sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Transient inhibition of angiotensinogen production in transgenic mice bearing an antisense angiotensinogen gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Ribozymes: A Distinct Class of Metalloenzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

The role of antisense RNA in gene regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Expression of a chimeric ribozyme gene results in endonucleolytic cleavage of target mRNA and a concomitant reduction of gene expression in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Gi alpha 2 mediates the inhibitory regulation of adenylylcyclase in vivo: analysis in transgenic mice with Gi alpha 2 suppressed by inducible antisense RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Higher level organization of individual gene transcription and RNA splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Role of I-A molecules in early stages of B cell maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Cytoplasmic delivery of ribozymes leads to efficient reduction in alpha-lactalbumin mRNA levels in C127I mouse cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active site

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Creating a conditional mutation of Wnt-1 by antisense transgenesis provides evidence that Wnt-1 is not essential for spermatogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Substrate sequence effects on "hammerhead" RNA catalytic efficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Antisense inhibition of gene expression: a tool for studying the role of NMYC in the growth and differentiation of neuroectoderm-derived cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Inhibition of human immunodeficiency virus type 1 multiplication by antisense and sense RNA expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3' untranslated region of the mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Inhibition of pancreatic beta-cell glucokinase by antisense RNA expression in transgenic mice: mouse strain-dependent alteration of glucose tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Protein enhancement of hammerhead ribozyme catalysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Ribozymes correctly cleave a model substrate and endogenous RNA in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Partial rescue of a lethal phenotype of fragile bones in transgenic mice with a chimeric antisense gene directed against a mutated collagen gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

5′-Terminal structure and mRNA stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Expression of GLUT-2 antisense RNA in beta cells of transgenic mice leads to diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Inhibition of Moloney murine leukemia virus-induced leukemia in transgenic mice expressing antisense RNA complementary to the retroviral packaging sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Antisense RNA complementary to 3' coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Mechanisms of mRNA decay

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Evaluation of an antisense RNA transgene for inhibiting growth hormone gene expression in transgenic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Conversion of normal behavior to shiverer by myelin basic protein antisense cDNA in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Differential antisense transcription from the Dictyostelium EB4 gene locus: implications on antisense-mediated regulation of mRNA stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Induction of G alpha i2-specific antisense RNA in vivo inhibits neonatal growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Making sense from antisense: a review of experimental data and developing ideas on sense--antisense peptide recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Ribozymes as potential anti-HIV-1 therapeutic agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Reduced beta 2-microglobulin mRNA levels in transgenic mice expressing a designed hammerhead ribozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Altered expression of nerve growth factor in the skin of transgenic mice leads to changes in response to mechanical stimuli.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Biological regulation by antisense RNA in prokaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Studies on the hammerhead RNA self-cleaving domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Disruption of hypothalamic-pituitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: effects on T cell trafficking and T cell responsiveness during p

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Antisense RNA production in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Growth retardation in rats whose growth hormone gene expression was suppressed by antisense RNA transgene

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

The IS10 antisense RNA blocks ribosome binding at the transposase translation initiation site

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Ionic requirements for RNA binding, cleavage, and ligation by the hairpin ribozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Biological and functional aspects of catalytic RNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Specific gene suppression by engineered ribozymes in monkey cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Attenuation of white gene expression in transgenic Drosophila melanogaster: possible role of a catalytic antisense RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication--potential effectiveness against most presently sequenced HIV-1 isolates

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Organ-specific modulation of gene expression in transgenic plants using antisense RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Site-specific cleavage by metal ion cofactors and inhibitors of M1 RNA, the catalytic subunit of RNase P from Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Inhibition of thymidine kinase gene expression by anti-sense RNA: A molecular approach to genetic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Injected anti-sense RNAs specifically block messenger RNA translation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Ribosome pausing and stacking during translation of a eukaryotic mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Inhibition of c-erbA mRNA splicing by a naturally occurring antisense RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Dexamethasone nonsuppression in transgenic mice expressing antisense RNA to the glucocorticoid receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Nuclear and cytoplasmic sites for anti-sense control

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Inhibition of tobacco NADH-hydroxypyruvate reductase by expression of a heterologous antisense RNA derived from a cucumber cDNA: implications for the mechanism of action of antisense RNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

A small catalytic oligoribonucleotide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Phenocopy of discoidin I-minus mutants by antisense transformation in Dictyostelium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

In vivo infection of sheep by bovine leukemia virus mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Visualization of RNA transcription and processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/8840519

12 December 2020

Identifiers

DOI

10.1007/BF01980201

1 reference

Dimensions Publication ID

24 September 2017

1008481960

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