Fibroblast growth factor 21 (Q21172808)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NSA1

Cytokine IL1/FGF

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NSA1

image

FGF21.png
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0 references

1 reference

13 November 2019

1 reference

13 November 2019

3 references

8 April 2019

C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

8 April 2019

Different roles of N- and C- termini in the functional activity of FGF21

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

8 April 2019

FGF21 N- and C-termini play different roles in receptor interaction and activation

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

fibroblast growth factor receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

1 reference

8 April 2019

cell component

extracellular region

Identification of a novel FGF, FGF-21, preferentially expressed in the liver

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

8 April 2019

extracellular space

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

endothelial cell apoptotic process

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

positive regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

positive regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

positive regulation of glucose import

1 reference

8 April 2019

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

cell-cell signaling

1 reference

8 April 2019

Identification of a novel FGF, FGF-21, preferentially expressed in the liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

cellular response to glucose stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

fibroblast growth factor receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

1 reference

8 April 2019

regulation of low-density lipoprotein particle clearance

NAS

1 reference

8 April 2019

Fibroblast growth factor-21 (FGF21) regulates low-density lipoprotein receptor (LDLR) levels in cells via the E3-ubiquitin ligase Mylip/Idol and the Canopy2 (Cnpy2)/Mylip-interacting saposin-like protein (Msap)

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

response to nutrient levels

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

negative regulation of endothelial cell apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

response to activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

signal transduction

1 reference

8 April 2019

Identification of a novel FGF, FGF-21, preferentially expressed in the liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

cellular response to low-density lipoprotein particle stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

endoplasmic reticulum unfolded protein response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

negative regulation of neuron death

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

positive regulation of triglyceride catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

response to methionine

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

cellular response to glucagon stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NSA1