Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells (Q24337943)

receptor tyrosine kinase binding

GOA release 2020-03-11

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GOA release 2020-03-11

E Peles

1

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author name string

S S Bacus

2

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R A Koski

3

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H S Lu

4

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D Wen

5

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S G Ogden

6

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R B Levy

7

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Y Yarden

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms

8

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language of work or name

English

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publication date

3 April 1992

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published in

Cell

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volume

69

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issue

1

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page(s)

205-16

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cites work

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Differentiation of cultured human breast cancer cells (AU-565 and MCF-7) associated with loss of cell surface HER-2/neu antigen

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Isolation and characterization of a neu protein-specific activating factor from human ATL-2 cell conditioned medium

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Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

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Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function

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Signal transduction by receptors with tyrosine kinase activity

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The trk proto-oncogene encodes a receptor for nerve growth factor

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Receptor-like oncogenes: functional analysis through novel experimental approaches

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Eukaryotic protein kinases

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Biochemical analysis of the ligand for the neu oncogenic receptor

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Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

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Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

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The neu oncogene encodes an epidermal growth factor receptor-related protein

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Peptide growth factors are multifunctional

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The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

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Recent developments in the cell biology of basic fibroblast growth factor

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The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

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Direct interaction of a ligand for the erbB2 oncogene product with the EGF receptor and p185erbB2.

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Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

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erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

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Amplification of a novel v-erbB-related gene in a human mammary carcinoma

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Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

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The erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potency

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Growth factor receptor tyrosine kinases

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The transforming growth factor-beta family

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Multiple hormone interactions in the developmental biology of the mammary gland

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