Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. (Q34324135)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15173835%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15173835%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15173835%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

2

Polly Matzinger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15173835%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

publication date

1 June 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15173835%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

29 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15173835%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15173835%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15173835%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

469-478

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15173835%20AND%20SRC:MED&resulttype=core&format=json

Approaching the asymptote? Evolution and revolution in immunology

29 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Tolerance, danger, and the extended family

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Natural adjuvants: endogenous activators of dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Decoding the patterns of self and nonself by the innate immune system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Innate immune recognition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Molecular identification of a danger signal that alerts the immune system to dying cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

The extra domain A of fibronectin activates Toll-like receptor 4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Antibody-independent activation of the complement system by mitochondria is mediated by cardiolipin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Endotoxin-free heat-shock protein 70 fails to induce APC activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Heat-shock proteins as activators of the innate immune system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Immune system protects integrity of tissues.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Role of macrophages in vascular tissue remodelling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Soluble CD14 mediates efflux of phospholipids from cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

CD14-dependent internalization and metabolism of extracellular phosphatidylinositol by monocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Phosphatidylserine expression and phagocytosis of apoptotic thymocytes during differentiation of monocytic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Structure-activity relationship of synthetic toll-like receptor 4 agonists

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Leucine-rich repeats and pathogen recognition in Toll-like receptors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

MHC class I and class II structures

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Electrostatics in protein binding and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Chemical structure and immunobiological activity of lipid A from Prevotella intermedia ATCC 25611 lipopolysaccharide

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Pathophysiology of sickle cell disease: role of cellular and genetic modifiers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Roles of molecular chaperones in cytoplasmic protein folding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Review: mechanisms of disaggregation and refolding of stable protein aggregates by molecular chaperones

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Activation of heat-shock response by an adenovirus is essential for virus replication.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Ion channel formation and membrane-linked pathologies of misfolded hydrophobic proteins: the role of dangerous unchaperoned molecules

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

A novel type of binding specificity to phospholipids for rat mannose-binding proteins isolated from serum and liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Apolipoprotein A-II modulates the binding and selective lipid uptake of reconstituted high density lipoprotein by scavenger receptor BI.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro: calreticulin and CD91 as a common collectin receptor complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Structure-function relationships of apolipoprotein A-I: a flexible protein with dynamic lipid associations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

ABC transporters in lipid transport

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

NODs: intracellular proteins involved in inflammation and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Mycoplasma fermentans lipoprotein M161Ag-induced cell activation is mediated by Toll-like receptor 2: role of N-terminal hydrophobic portion in its multiple functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Adhesion of uric acid crystals to the surface of renal epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Analysis of the Interaction of Small Heat Shock Proteins with Unfolding Proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

The chaperonin GroEL is destabilized by binding of ADP

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Hyaluronan: Preparation, Structure, Properties, and Applications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Titration calorimetric studies to elucidate the specificity of the interactions of polymyxin B with lipopolysaccharides and lipid A.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Lipid binding and membrane penetration of polymyxin B derivatives studied in a biomimetic vesicle system.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Role of activation of the coagulation factor VIII in interaction with vWf, phospholipid, and functioning within the factor Xase complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Sequence analysis of an artificial family of RNA-binding peptides

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Isolation and characterization of a complement-activating lipid extracted from human atherosclerotic lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Adsorption of fibrinogen to droplets of liquid hydrophobic phases. Functionality of the bound protein and biological implications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Essential roles of CD14 and lipopolysaccharide-binding protein for activation of toll-like receptor (TLR)2 as well as TLR4

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Phagocytosis as a Surface Phenomenon

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Membrane phospholipid asymmetry as a determinant of erythrocyte recognition by macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

CD14 is a component of multiple recognition systems used by macrophages to phagocytose apoptotic lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

The physiological structure of human C-reactive protein and its complex with phosphocholine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiinflammatory innate immune response: implications for systemic autoimmunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Class A scavenger receptors and the phagocytosis of apoptotic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Is the class A macrophage scavenger receptor (SR-A) multifunctional? - The mouse's tale

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Oxidized LDL-induced NF-kappa B activation and subsequent expression of proinflammatory genes are defective in monocyte-derived macrophages from CD36-deficient patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Molecular flypaper and atherosclerosis: structure of the macrophage scavenger receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Evidence that the lipid moiety of oxidized low density lipoprotein plays a role in its interaction with macrophage receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Cutting edge: the toll pathway is required for resistance to gram-positive bacterial infections in Drosophila

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Toll-like receptor 4 and atherogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

The role of hemolymph coagulation in innate immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Scavenger receptor family proteins: roles for atherosclerosis, host defence and disorders of the central nervous system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Protein structure and folding: a new start.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Solvation energy in protein folding and binding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Developmental and pathogen-induced expression of three barley genes encoding lipid transfer proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Inducibility by pathogen attack and developmental regulation of the rice Ltp1 gene.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Plant disease resistance triggered by pathogen-derived molecules: refined models of specific recognition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Insect immune activation by apolipophorin III is correlated with the lipid-binding properties of this protein.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Vgamma9Vdelta2 T cells recovered from eyes of patients with Behçet's disease recognize non-peptide prenyl pyrophosphate antigens

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Cholesterol in the year 2000.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

A continuum of anionic charge: structures and functions of D-alanyl-teichoic acids in gram-positive bacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Clinical spectrum of paradoxical deterioration during antituberculosis therapy in non-HIV-infected patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Malaria-induced acquisition of antibodies to plasmodium falciparum variant surface antigens

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Anti-inflammatory lipid mediators and insights into the resolution of inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Biological activities of lipopolysaccharides are determined by the shape of their lipid A portion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Influence of the supramolecular structure of free lipid A on its biological activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Supramolecular structure of lipopolysaccharide and free lipid A under physiological conditions as determined by synchrotron small-angle X-ray diffraction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Intrinsic conformation of lipid A is responsible for agonistic and antagonistic activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

The generalized endotoxic principle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Host defence capacities of pulmonary surfactant: evidence for 'non-surfactant' functions of the surfactant system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Neutralization and transfer of lipopolysaccharide by phospholipid transfer protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Lipopolysaccharide (LPS)-binding protein mediates LPS detoxification by chylomicrons

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Induction of cytokine tolerance requires internalization of Chylomicron-Bound LPS into hepatocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

The phosphatidylserine receptor: a crucial molecular switch?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Prostaglandin E2 inhibits TNF production in murine bone marrow-derived dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: consequences for the immune response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

RORalpha1 and RORalpha4 suppress TNF-alpha-induced VCAM-1 and ICAM-1 expression in human endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Co-stimulation and co-inhibition: equal partners in regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Quorum sensing and biofilm formation in Streptococcal infections

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

The Human Type I Interferon Receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Structural characterization of the human respiratory syncytial virus fusion protein core

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Structural basis of chaperone function and pilus biogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

Conformational variability in the refined structure of the chaperonin GroEL at 2.8 A resolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

The central role of phosphatidylserine in the phagocytosis of apoptotic thymocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

inferred from DOI database lookup

7 January 2021

based on heuristic

The human type I interferon receptor: NMR structure reveals the molecular basis of ligand binding

1 reference

https://api.crossref.org/works/10.1038%2FNRI1372

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1372

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15173835%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference