Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis (Q27639235)

2

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Timothy N Breece

3

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Leonard G Presta

4

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Abraham M de Vos

5

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Sachdev S Sidhu

Journal of Molecular Biology

6

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language of work or name

English

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publication date

5 July 2002

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published in

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volume

320

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issue

2

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page(s)

415-28

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cites work

Recombinant antibody constructs in cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Conformations of immunoglobulin hypervariable regions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Three-dimensional structure of an idiotope–anti-idiotope complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

18 Systematic mutational analyses of protein-protein interfaces

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

A hot spot of binding energy in a hormone-receptor interface

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Thermodynamic analysis of an antibody functional epitope

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

In vitro scanning saturation mutagenesis of all the specificity determining residues in an antibody binding site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Rapid mapping of protein functional epitopes by combinatorial alanine scanning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Modulation of antibody affinity by a non-contact residue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

On the nature of antibody combining sites: Unusual structural features that may confer on these sites an enhanced capacity for binding ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Phage display in pharmaceutical biotechnology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

"ATG vectors' for regulated high-level expression of cloned genes in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

DNA Sequence Analysis of the Type-Common Glycoprotein-D Genes of Herpes Simplex Virus Types 1 and 2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Selecting high-affinity binding proteins by monovalent phage display

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Phage display for selection of novel binding peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Rapid and efficient site-specific mutagenesis without phenotypic selection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

The Rossmann Fourier autoindexing algorithm in MOSFLM

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

The CCP4 suite: programs for protein crystallography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

On the treatment of negative intensity observations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

AMoRe: an automated package for molecular replacement

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

Improved Fourier coefficients for maps using phases from partial structures with errors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

7 January 2021

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900264-4

10.1016/S0022-2836(02)00264-4

7 January 2021

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12079396

1 reference

Consolidated OpenCitations Corpus – April 2017