New targets for anti-inflammatory drugs (Q33695752)

28 July 2017

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title

New targets for anti-inflammatory drugs (English)

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28 July 2017

Lewis AJ

1

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28 July 2017

Manning AM

series ordinal

2

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28 July 2017

publication date

1 August 1999

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Current Opinion in Chemical Biology

28 July 2017

published in

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28 July 2017

volume

3

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28 July 2017

issue

4

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28 July 2017

page(s)

489-494

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Treatment of asthma with drugs modifying the leukotriene pathway.

28 July 2017

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Anticytokine therapy--a new era in the treatment of rheumatoid arthritis?

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Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist

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Gene therapy for rheumatic diseases

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7 January 2021

Human chemokines: an update

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Chemokines and leukocyte traffic

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7 January 2021

Opportunities for novel therapeutic agents acting at chemokine receptors

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7 January 2021

Signal transduction and transcription factors in rheumatic disease

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7 January 2021

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

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Ternary complex factors: growth factor regulated transcriptional activators

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7 January 2021

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

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7 January 2021

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

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7 January 2021

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

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AP-1 function and regulation

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7 January 2021

Defective T Cell Differentiation in the Absence of Jnk1

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7 January 2021

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

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7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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7 January 2021

Pharmacological modulation of cytokine action and production through signaling pathways

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7 January 2021

Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)

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7 January 2021

Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta

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7 January 2021

The search for physiological substrates of MAP and SAP kinases in mammalian cells

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7 January 2021

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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7 January 2021

Ro 09-2210 exhibits potent anti-proliferative effects on activated T cells by selectively blocking MKK activity

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7 January 2021

Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket

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7 January 2021

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

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7 January 2021

Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution

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7 January 2021

Pyrroles and other heterocycles as inhibitors of p38 kinase

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7 January 2021

6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2, 3-b]pyridine (RWJ 68354): a potent and selective p38 kinase inhibitor

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7 January 2021

Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway

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7 January 2021

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

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7 January 2021

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

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7 January 2021

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

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7 January 2021

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

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7 January 2021

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

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7 January 2021

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7 January 2021

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

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7 January 2021

Activation of IkappaB kinase beta by protein kinase C isoforms

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7 January 2021

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

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7 January 2021

10.1016/S1367-5931(99)80071-4

Identifiers

DOI

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28 July 2017

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