Scribd Logo
Upload

Welcome to Scribd!

  • 226 views

    Nephrotic Vs Nephritic Syndrome

    Uploaded by

    SS
    This document provides an overview of the differences between nephrotic syndrome and nephritic syndrome. Nephrotic syndrome is defined by massive proteinuria and hypoalbuminemia, causing edema. Nephritic syndrome involves hematuria, mild to moderate proteinuria, hypertension, oliguria, and red blood cell casts, indicating glomerular damage. The document outlines key clinical features, symptoms, and urinalysis findings that distinguish the two conditions.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Nephrotic Vs Nephritic Syndrome

    Uploaded by

    SS
    226 views2 pages
    This document provides an overview of the differences between nephrotic syndrome and nephritic syndrome. Nephrotic syndrome is defined by massive proteinuria and hypoalbuminemia, causing edema. Nephritic syndrome involves hematuria, mild to moderate proteinuria, hypertension, oliguria, and red blood cell casts, indicating glomerular damage. The document outlines key clinical features, symptoms, and urinalysis findings that distinguish the two conditions.

    Original Title

    geekymedics.com-Nephrotic vs Nephritic Syndrome

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    This document provides an overview of the differences between nephrotic syndrome and nephritic syndrome. Nephrotic syndrome is defined by massive proteinuria and hypoalbuminemia, causing edema. Nephritic syndrome involves hematuria, mild to moderate proteinuria, hypertension, oliguria, and red blood cell casts, indicating glomerular damage. The document outlines key clinical features, symptoms, and urinalysis findings that distinguish the two conditions.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    226 views2 pages

    Nephrotic Vs Nephritic Syndrome

    Uploaded by

    SS
    This document provides an overview of the differences between nephrotic syndrome and nephritic syndrome. Nephrotic syndrome is defined by massive proteinuria and hypoalbuminemia, causing edema. Nephritic syndrome involves hematuria, mild to moderate proteinuria, hypertension, oliguria, and red blood cell casts, indicating glomerular damage. The document outlines key clinical features, symptoms, and urinalysis findings that distinguish the two conditions.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 2

    Nephrotic vs Nephritic Syndrome

    geekymedics.com/nephrotic-vs-nephritic-syndrome/

    Dr Lewis Potter October 26, 2010

    This article provides a very brief overview ofnephrotic and nephritic syndrome, to help you
    differentiate between them.

    Nephrotic syndrome
    Nephrotic syndrome is a condition involving the loss of significant volumes of protein via the
    kidneys (proteinuria) which results in hypoalbuminaemia. The definition of nephrotic
    syndrome includes both massive proteinuria (≥3.5 g/day) and hypoalbuminaemia (serum albumin
    ≤30 g/L). 1

    Clinical Features
    As a result of hypoalbuminaemia, nephrotic syndrome is associated withoedema (due to reduced
    oncotic pressure), hyperlipidaemia and hypercoagulability.

    Symptoms
    Peripheral oedema (more common in adults)
    Facial oedema (more common in children)
    Frothiness of urine
    Fatigue
    Poor appetite
    Recurrent infections (due to immune dysfunction)
    Venous or arterial thrombosis (e.g. myocardial infarction, deep vein thrombosis) due to
    hypercoagulability

    Signs
    Oedema (e.g. peri-orbital, lower limb, ascites)
    Xanthelasma and/or xanthoma
    Leukonychia
    Shortness of breath (with associated chest signs of pleural effusion – e.g. stony dullness in
    lung bases)

    1/2
    Urinalysis
    Proteinuria (protein ++++)
    Frothy appearance

    Nephritic syndrome
    Nephritic syndrome is a condition involving haematuria, mild to moderate proteinuria (typically
    less than 3.5g/L/day), hypertension, oliguria and red cell casts in the urine.

    Clinical Features

    Symptoms
    Haematuria (can be frank haematuria or microscopic)
    Oedema (to a lesser extent compared to nephrotic syndrome)
    Reduced urine output
    Uraemic symptoms (e.g. reduced appetite, fatigue, pruritus, nausea)

    Signs
    Haematuria (either visible or detectable on urinalysis)
    Oedema
    Hypertension
    Oliguria (<300mls/day)

    Urinalysis
    Haematuria (blood +++)
    Proteinuria (mild – protein ++)
    Red cell casts – distinguishing feature of nephritic syndrome, form in nephrons and indicate
    glomerular damage

    References
    1. Nishi S, Ubara Y, Utsunomiya Y, et al; Evidence-based clinical practice guidelines for
    nephrotic syndrome 2014. Clin Exp Nephrol. 2016 Jun20(3):342-70. doi: 10.1007/s10157-
    015-1216-x.
    2. Dr Colin Tidy. Patient.info. Acute Nephritis. Published: 21st June 2016. Available from:
    [LINK]

    2/2

    You might also like