Mice News

January 5, 2025

Top Headlines

Researchers Discover Class of Anti-Malaria Antibodies

Jan. 3, 2025 — Antibodies that bind to a previously untargeted portion of the malaria parasite could lead to new monoclonal antibody treatments and vaccines for ...

Scientists Unveil Surprising Human Vs Mouse Differences in a Major Cancer Immunotherapy Target

Jan. 3, 2025 — Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment of PD-1, researchers have found that PD-1 in mice is ...

Zebrafish Protein Unlocks Dormant Genes for Heart Repair

Jan. 2, 2025 — Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating ...

Key Players in Brain Aging: New Research Identifies Age-Related Damage on a Cellular Level

Jan. 1, 2025 — Scientists have identified the molecular changes that occur in the brains of aging mice and located a hot spot where much of that damage is centralized. The cells in the area are also connected with ...

Latest Headlines

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Shiitake-Derived Functional Food Shows Suppression of Liver Fibrosis Progression

Dec. 19, 2024 — A research team found out how AHCC, a standardized extract of cultured Lentinula edodes mycelia, might be able to suppress the progression of liver ...

How a New Gut Microbe Drives the Gut-Lung Axis

Dec. 19, 2024 — A team has discovered a new communication pathway between the gut and lung. Their findings highlight how a little-known member of the gut microbiome reshapes the lung immune environment to have both ...

Brain Inflammation Alters Behavior According to Sex, Mouse Study Finds

Dec. 19, 2024 — Inflammation in the hippocampus -- the brain's memory center -- significantly alters motivation and behavior in mice, according to new ...

The Longevity Factor Foxo3 Mediates 'Unfit' Cell Elimination to Ensure Healthy Body Construction

Dec. 17, 2024 — Researchers have revealed some of the precise mechanisms by which erroneous cells are recognized, marked for removal, and eliminated via apoptosis in ...

Discouraged Zebrafish Help Reveal How Ketamine Works in the Brain

Dec. 17, 2024 — By taking advantage of a 'giving up' behavior exhibited by zebrafish, the ability to image the fish's entire brain, and a unique virtual reality system, a team of researchers found where ketamine ...

Researchers Discover New Neurons That Suppress Food Intake

Dec. 5, 2024 — Researchers have discovered a new population of neurons that is responsive to the hormone leptin. Leptin responsive neurons are important in obesity since leptin is sent to the brain from the body's ...

Flavonoid Powerhouse: Kaempferol's Role in Taming Allergic Responses

Dec. 16, 2024 — Food allergies affect millions of people worldwide, and flavonoids are promising natural compounds to help modulate the immune response and treat inflammation caused by these allergies. In a recent ...

Staphylococcus Aureus Thwarts Vaccines by Turning on a Protein That Halts Immune Response

Dec. 16, 2024 — After dozens of clinical trials, there are still no effective vaccines against Staphylococcus aureus. In two new studies, scientists report that the ...

A Lipid Nanoparticle Delivers mRNA Cure for Pre-Eclampsia in Mice

Dec. 11, 2024 — Engineers have developed a lipid nanoparticle (LNP) that delivers mRNA therapeutic to the placenta to treat pre-eclampsia in mice with human trials on the ...

Intermittent Fasting Inhibits Hair Regeneration in Mice

Dec. 13, 2024 — Intermittent fasting has proven benefits for metabolic health, but a new study shows that it could slow hair growth -- at least in mice. Researchers report that mice subjected to intermittent fasting ...

The Maternal Microbiome During Pregnancy Impacts Offspring's Stem Cells in Mice

Dec. 11, 2024 — Gut microbiome composition during pregnancy has long-term effects on offspring stem cell growth and development, researchers report. Treating pregnant mice with a common gut microbe resulted in ...

Scientists Transform Ubiquitous Skin Bacterium Into a Topical Vaccine

Dec. 11, 2024 — Scientists' findings in mice could translate into a radical, needle-free vaccination approach that would also eliminate reactions including fever, swelling and ...

Study Breaks the Silence on How Fish and Lizards Regenerate Hearing

Dec. 9, 2024 — A new study has identified key gene regulators that enable some deafened animals -- including fish and lizards -- to naturally regenerate their hearing. The findings could guide future efforts to ...

Keto Diet Metabolite May Power Up CAR T Cells to Kill Cancer

Dec. 7, 2024 — A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a new ...

CAST Mouse Model: A Crucial Tool for Future COVID-19 Outbreaks

Dec. 6, 2024 — Researchers have identified the first mouse strain that is susceptible to severe COVID-19 without the need for genetic modification. This development marks a pivotal step forward in infectious ...

Mothers Massively Change Their Intestines During Pregnancy and Nursing

Dec. 5, 2024 — When women are pregnant and nurse their babies, their bodies change and various organs, such as the breasts or the immune system, are adapted to ensure the health of both mother and child. This ...

Lasting Effects of Common Herbicide on Brain Health

Dec. 4, 2024 — New research identifies an association between glyphosate exposure in mice and symptoms of neuroinflammation, as well as accelerated Alzheimer's disease-like pathology. This study tracks both ...

The Secret to Our Big Brains Might Be in Our Gut

Dec. 4, 2024 — Brain tissue is among the most energetically costly in the body, and as a result, larger-brained mammals require more energy to support brain growth and maintenance. Exactly which biological changes ...

Scientists Identify Brain Cell Type as Master Controller of Urination

Dec. 3, 2024 — Researchers have identified a subset of brain cells in mice that act as the master regulators of ...

Controlling a Cancer-Associated Gene Can Mimic Muscle Growth from Exercise

Dec. 3, 2024 — Knowing the precise mechanisms by which MYC drives muscle growth could prove instrumental in creating therapies that reduce muscle loss from aging, potentially improving independence, mobility and ...

Pregnancy Enhances Natural Immunity to Block Severe Flu

Dec. 2, 2024 — Scientists have discovered that pregnancy may trigger a natural immunity to boost protection against severe flu infection. Contrary to the common belief that pregnancy increases vulnerability to ...

A Bodily Balancing Act: Breakthrough Discovery Identifies Key Factor for Balancing Saturated and Unsaturated Fatty Acids in the Body

Dec. 2, 2024 — Researchers have identified ARMC5 as a key regulator of fatty acid balance in adipose tissue. ARMC5 degrades non-SCAP-bound SREBP1, activating it to regulate stearoyl-CoA desaturase (SCD), an enzyme ...

Study May Reverse Century-Old Understanding of the Shape of 'Arms' on Mammals' Brain Cells

Dec. 2, 2024 — Biology textbooks may need a revision, say scientists, who present new evidence that an arm-like structure of mammalian brain cells may be a different shape than scientists have assumed for more than ...

Mouse Study Captures Aging Process at the Cellular Level

Dec. 2, 2024 — As muscles age, their cells lose the ability to regenerate and heal after injury. Now, researchers have created the most comprehensive portrait to date of how that change, in mice, unfolds over ...

What a Gut Fungus Reveals About Symbiosis and Allergy

Nov. 27, 2024 — A fungus discovered in the mouse stomach may hold a key to fungal evolution within the gastrointestinal tract, according to new research. The finding suggests that preclinical studies until now have ...

Great Apes Visually Track Subject-Object Relationships Like Humans Do, Study Finds

Nov. 26, 2024 — Great apes track events with their eyes in the same way that humans do, according to a new ...

Nerve Cells of Blind Mice Retain Their Visual Function

Nov. 26, 2024 — Using microelectrodes, scientists could show that cells in the retina play different roles. The produce different signals, which is important for the processing of visual information. These ...

Machine Learning Reveals Behaviors Linked With Early Alzheimer's, Points to New Treatments

Nov. 26, 2024 — Scientists used a new video-based machine learning tool to pinpoint otherwise-undetectable signs of early disease in mice that were engineered to mimic key aspects of Alzheimer's. Their work ...

Researchers Find That Intestinal Infections Change Bile Composition

Nov. 26, 2024 — Researchers have identified a new axis of host defense by studying what happens during enteric infection -- a term that encompasses all types of intestinal infections including so called ...

Pandrug-Resistant Bacteria from the War in Ukraine Are Extremely Pathogenic

Nov. 25, 2024 — It has been a year ago since bacteria from war-wounded at hospitals in Ukraine were analyzed. The study showed that some of the bacteria types had total resistance to antibiotics. Now, the same ...