Danny DeVito, who plays Kominsky's urologist, goes back to the 1960's with Michael Douglas; had a role in Douglas's production, One Flew Over the Cuckoo's Nest; co-starred with him in both Romancing the Stone and its sequel, Jewel of the Nile; and directed him in War of the Roses.
Danny Devito appeared in One Flew Over The Cuckoo's Nest (1975) of which Michael Douglas was at one point going to star, but instead stayed on as producer.