- Dr. Hannibal Lecter: I have let you know me, see me. I gave you a rare gift, but you didn't want it.
- Will Graham: Didn't I?
- Dr. Hannibal Lecter: What we do for ourselves dies with us. What we do for others, that's beyond us.
- Dr. Hannibal Lecter: You would deny me my life.
- Will Graham: No, not your life, no.
- Dr. Hannibal Lecter: My freedom then, you would take that from me. Confine me in a prison cell. Do you believe you could change me, the way I've changed you?
- Will Graham: I already did.
- Dr. Hannibal Lecter: Fate and circumstance have returned us to this moment, when the teacup shatters. I forgive you, Will. Will you forgive me?
- Dr. Hannibal Lecter: You can make it all go away. Put your head back. Close your eyes. Wade into the quiet of the stream.
- Dr. Hannibal Lecter: In the walls of our hearts and brains, danger waits. There are holes in the floor of the mind.
- Jack Crawford: [Jack about to arrest Hannibal] I want to thank you, Dr. Lecter, for your friendship.
- Dr. Hannibal Lecter: The most beautiful quality of a true friendship is to understand and be understood with absolute clarity.
- Jack Crawford: Then this is the clearest moment of our friendship.