Mom has bought Planet Express Deliveries from Professor Farnsworth and has gained control over planet earth. It's up to the player's crew (Fry, Leela, Dr. Zoidberg, Bender, ...) to stop her evil plans.
When Professior Farnsworth sells Planet Express to the evil Mom, it means she owns over 50% of the Earth, and becomes it's supreme ruler. It's up to Fry, Leela and Bender to save the Earth - and the universe - from Mom, as their mission takes them from New New York to alien asteroids, the surface of the sun, the farthest corner of the universe, and even through time itself!—Chris McFeely