The Dinosaur effects were created by the same team that had just completed the now-legendary Walking with Dinosaurs (1999) TV series. In addition, the Entelodont from Walking with Prehistoric Beasts (2001) makes an appearance.
Brian Blessed was the original choice for the Bob Hoskins role but his casting was vetoed by the American networks.
Matthew Rhys (Edward Malone) starred alongside Peter Falk in this production. Two years later Rhys would star alongside Falk again to play the last ever murderer in the last ever Columbo episode Columbo: Columbo Likes the Nightlife (2003).
Professor Challenger talks to Summerlee about his life as a young boy, that he was raised by his parents under the Bible. Then as he became more interested in Science, his father had "lost" him. This is similar to his creator, Sir Arthur Conan Doyle, and his own religious experiences. He too, was a scientist that was raised Catholic and became more supportive of Spiritualism.
Of all the movie versions of "The Lost World," this is the only one set at an earlier time than Doyle's original novel. The book took place in 1912, and The Lost World (2001) is set in 1911.