The character Tony Rome appeared in three novels by Marvin H. Albert in the early 1960s: "Miami Mayhem" (filmed as this movie), Lady in Cement (1968) (filmed under the same name), and "My Kind of Game."
Tony Rome's convertible car is a 1961 Ford Galaxie Sunliner.
Templeton Fox, who plays Mrs. Schuyler (the pussycat lady), is the mother, with Robert L. Welch, of Fleetwood Mac guitarist Bob Welch (writer of "Sentimental Lady").
Stella Stevens turned down the role that was subsequently accepted by Jill St. John. Stevens had a one time date with Frank Sinatra a few years prior. He was looking for a relationship with a woman not interested in a career of her own and spent the entire date trying to talk Stevens into giving up hers. It was their first and last date, and she didn't want to work with him.
The beach parking lot that Tony Rome drives through before stopping at the hotel early in the movie was Pier Park at the corner of 1st Street and Ocean Drive. It is currently (as of June 2022) the site of Nikki Beach Club.