When Maureen O'Sullivan first met Clark Gable on the set, he was in his old-age makeup. He asked her out on a horseback-riding date, but thinking he was too old for her, she turned him down. Later when she was doing some voice-overs, she saw him without makeup and regretted her decision. Gable never asked her out again.
Of all the films adapted from his plays released in his lifetime, this film is the adaptation Eugene O'Neill reportedly liked the least, maintaining that Hollywood had "censored it into near-imbecility".
When M-G-M Executive Producer Irving Thalberg bought the rights to the play, "Strange Interlude," he originally planned to have the leads played by Lynn Fontanne, who played the lead on Broadway, and her famous husband Alfred Lunt. But, the couple turned it down because they weren't interested in making movies. Thalberg then decided to use his wife Norma Shearer and Clark Gable instead. Gable was at first intimidated, but agreed.